The Holst Memorial Lecture 2011 and Symposium are organized by Philips Research and the Technische Universiteit Eindhoven (TU/e). This year’s Symposium and Memorial Lecture will address innovative methods to explore molecular and cellular mechanisms of heart disease and regeneration, and emerging therapies for heart repair. Eminent speakers will present their views on recent and future developments in their specific disciplines.This year’s Holst Lecture, the 35th since 1977, will be held by Donald E. Ingber M.D., Ph.D., Founding Director Wyss Institute for Biologically Inspired Engineering at Harvard University.