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A fluorescence microscopic image shows the retinal vascular network of the newborn mouse, which has been slowed in its development by genetically manipulating this mechanosensitive transcriptional control system.

Angiogenesis -- the growth of blood capillaries -- is critical for normal development, and leads to many diseases, including blindness, when deregulated.

Fluorescent micrograph showing focal adhesion anchoring complexes, actin filament bundles, and nuclei of a spread endothelial cel.

The microtubule filaments of the cytoskeleton of a cultured capillary endothelial are revealed by expressing green fluorescent protein (GFP).