Project ABBIE: Early Detection and Prevention of Anaphylaxis
According to the Asthma & Allergy Foundation of America (AAFA), over 15 million Americans are at risk of anaphylaxis, and every three minutes a food reaction sends someone to the emergency department. In most individuals, the anaphylactic escalation that leads to shock can be prevented by administering the counteracting drug, epinephrine. Yet, despite effective treatments, anaphylaxis fatalities are still common and prevention remains difficult to achieve. Due to the rapid and unrelenting progression of symptoms, tragedy strikes when life-saving epinephrine cannot be injected into anaphylaxis-stricken individuals immediately following initiation of an attack.
The Wyss Institute and the KeepSmilin4Abbie Foundation have partnered to advance research and development efforts in the early detection and treatment of anaphylaxis, a severe allergic reaction triggered by exposure to certain foods, materials, medications and insect bites. The partnership aims to develop a deep understanding of the processes heralding an oncoming anaphylactic episode at the earliest stages.
The immediate goal of the effort is to understand the physiological and biochemical signals that indicate anaphylaxis and develop a wearable device that continually monitors these signals.
The device would be able to intervene, saving the lives of at-risk children and adults who suffer from severe allergies.
- The Wyss Institute and KeepSmilin4Abbie Foundation Join Forces Towards Early Detection and Prevention of Anaphylaxis, Learn more…
- KeepSmilin4Abbie May 2 "Day at the Derby" Event featured on HCAM TV, Learn more…
| Benjamin Matthews, M.D.
Don Ingber, M.D., Ph.D.
Founding Director, Wyss Institute
Jim Niemi, M.S.
Lead Senior Staff Engineer
John Osborne, M.S.
Senior Staff Engineer
Mustafa Karabas, M.S.
Staff Mechanical Engineer
Business Development Lead
Olivier Henry, Ph.D.
Alan Dunne, M.Eng.Sc.
Staff Research Engineer
Co-Founder, Executive Director
Program Contact: John Osborne, firstname.lastname@example.org