Wyss InstituteHealthy Aging – Wyss Institute https://wyss.harvard.edu Wyss Institute at Harvard Thu, 16 Apr 2026 18:53:44 +0000 en-US hourly 1 https://wordpress.org/?v=6.7.1 How federal funds fuel life-saving innovation https://wyss.harvard.edu/news/how-federal-funds-fuel-life-saving-innovation/ Thu, 20 Nov 2025 17:49:40 +0000 https://wyss.harvard.edu/?p=44198 Foundational breakthroughs enabled by government research grants lead to technologies changing patients’ lives for the better

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]]> https://wyss.harvard.edu/news/how-federal-funds-fuel-life-saving-innovation/ Researchers put a lot of effort into preparing extensive grant applications, which then go through a lengthy review process. A small percentage receive funding. Credit: Wyss Institute at Harvard University https://wyss-prod.imgix.net/app/uploads/2025/11/12163644/Kiley-Baker-and-Keysa-Garcia-Candid-Color-Corrected_04289-scaled.jpg?auto=format%2Ccompress&crop=faces%2Centropy&fit=crop&h=400&q=50&w=300&s=93f76f74996be3212132d618d4328d19"/> Crossing the barrier: Wyss Brain Targeting Program is delivering on its promise https://wyss.harvard.edu/news/crossing-the-barrier-wyss-brain-targeting-program-is-delivering-on-its-promise/ Wed, 22 Oct 2025 13:18:46 +0000 https://wyss.harvard.edu/?p=43961 Collaboration catalyzes industry progress By Seth Kroll (BOSTON) — Launched in 2019 as an ambitious idea, the Wyss Brain Targeting Program was designed to address a critical challenge in neuroscience and brain health: how to safely and effectively deliver drugs across the blood-brain barrier (BBB). The BBB is a tightly regulated gateway that protects the brain from toxins and pathogens but also prevents nearly all large-molecule drugs…

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]]> https://wyss.harvard.edu/news/crossing-the-barrier-wyss-brain-targeting-program-is-delivering-on-its-promise/ The Wyss Brain Targeting team. Credit: Wyss Institute at Harvard University https://wyss-prod.imgix.net/app/uploads/2025/10/28095702/BTP-Team-Photo.png?auto=format%2Ccompress&crop=faces%2Centropy&fit=crop&h=400&q=50&w=300&s=0a76c222515163d27fa951a1233a6aaa"/> GeneSkin: A Novel mRNA Therapy for Skin and Hair Rejuvenation https://wyss.harvard.edu/technology/geneskin-a-novel-mrna-therapy-for-skin-and-hair-rejuvenation/ Thu, 25 Sep 2025 13:44:27 +0000 https://wyss.harvard.edu/?post_type=technology&p=42913 More than 1.9 billion people worldwide suffer from some form of skin disease or cosmetic issue, including acne, eczema, scars, wrinkles, and hair loss. However, dermatological research has only brought limited therapeutic progress for skin rejuvenation, scar treatment, and hair loss in recent decades. While many of these conditions share a common root in the declining function of the skin’s stem…

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]]> https://wyss.harvard.edu/technology/geneskin-a-novel-mrna-therapy-for-skin-and-hair-rejuvenation/ Credit: Envato/BLACKDAY https://wyss-prod.imgix.net/app/uploads/2025/06/03133310/woman-with-a-scar-on-her-shoulder-2024-10-17-15-24-50-utc-scaled.jpg?auto=format%2Ccompress&crop=faces%2Centropy&fit=crop&h=400&q=50&w=300&s=9d046733faaa4609c5bc35b8aaa3c287"/> Recapitulating egg and sperm development in the dish https://wyss.harvard.edu/news/recapitulating-egg-and-sperm-development-in-the-dish/ Fri, 15 Aug 2025 17:55:46 +0000 https://wyss.harvard.edu/?p=43314 New stem cell differentiation method is first to induce meiosis, a critical step in egg and sperm cell development, with potential for drug development and future fertility treatments By Benjamin Boettner (BOSTON) — More than one-sixth of adults around the world experience infertility in their lifetime. There is a high unmet need not only for increased access to affordable, high-quality fertility care for those in need but, importantly, also for new biomedical solutions that can address the root causes of infertility. Some of the earliest causes of infertility go back to…

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]]> https://wyss.harvard.edu/news/recapitulating-egg-and-sperm-development-in-the-dish/ https://wyss-prod.imgix.net/app/uploads/2025/07/16122007/Meiotic-features-in-iPSC-derived-cells-induced-to-differentiate-as-eggs-and-sperm_feature.jpg?auto=format%2Ccompress&crop=faces%2Centropy&fit=crop&h=400&q=50&w=300&s=025fe719d7e73d34266007ebf246a369"/> The Wyss Institute’s 2025-2026 Validation Projects https://wyss.harvard.edu/news/the-wyss-institutes-2025-2026-validation-projects/ Thu, 14 Aug 2025 15:00:53 +0000 https://wyss.harvard.edu/?p=43463 14 teams supported this year to advance projects with future potential for real-world impact through the Wyss’ technology innovation funnel Throughout recent years, the Wyss’ Validation Project mechanism has proven to be a highly valuable instrument for selecting and kick-starting projects with early potential for positive impact on healthcare and the environment. Reaching deep into areas with major unmet needs across the diverse Grand Challenges laid out by the Institute, the newly selected projects are driven by multi-talented teams…

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]]> https://wyss.harvard.edu/news/the-wyss-institutes-2025-2026-validation-projects/ Senior Scientist Kwasi Adu-Berchie (center) is leading the TIB project team with Core Faculty member David Mooney (left). The team is developing tolerance-inducing biomaterials to offer patients safer, longer-lasting treatments for conditions ranging from autoimmune disease to tissue and bone injury. Credit: Wyss Institute at Harvard University https://wyss-prod.imgix.net/app/uploads/2025/08/13101608/Dave-Mooney-Lab-Candid-Lab-Coat-07873-scaled.jpg?auto=format%2Ccompress&crop=faces%2Centropy&fit=crop&h=400&q=50&w=300&s=b0631ddd4c73659862b34b403e537e4f"/> Translational AI at the Wyss Institute: how artificial intelligence enables patient impact https://wyss.harvard.edu/news/translational-ai-at-the-wyss-institute-how-artificial-intelligence-enables-patient-impact/ Thu, 26 Jun 2025 13:00:39 +0000 https://wyss.harvard.edu/?p=43119 New Wyss Catalyst Embraces AI Landscape to Advance Innovation and Collaboration By Seth Kroll (BOSTON) – Artificial intelligence (AI) is rapidly permeating the modern technological landscape. While its rise often sparks debate and caution in broader society, many in the life sciences view AI as a wellspring of opportunity. Researchers and innovators are increasingly eager to harness its potential to accelerate the development of transformative drugs, diagnostics…

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]]> https://wyss.harvard.edu/news/translational-ai-at-the-wyss-institute-how-artificial-intelligence-enables-patient-impact/ Wyss Computational Scientist Megan Sperry describes how she is incorporating AI approaches to drive innovation in her work during a panel discussion with Ally Chang, Wyss Business Development Director, Jim Collins, Wyss Core Faculty, Milad Alucozai, Wyss Mentor & Co-Founder of Revalia Bio, Madhuri Roy, Partner at Cooley, Eric Kelsic, CEO & Co-Founder of Dyno Therapeutics, and Alex Sneider, Co-Founder & Head of Corporate Development at Lila Sciences. Credit: Wyss Institute at Harvard University https://wyss-prod.imgix.net/app/uploads/2025/06/19152255/Wyss2025_300-scaled-e1750361107680.jpg?auto=format%2Ccompress&crop=faces%2Centropy&fit=crop&h=400&q=50&w=300&s=717333c49be66edaf9e8df7da5e6330a"/> The End of Aging—And Extinction | George Church, Ph.D. on Longevity, Dire Wolves, and Woolly Mammoths https://wyss.harvard.edu/media-post/the-end-of-aging-and-extinction-george-church-ph-d-on-longevity-dire-wolves-and-woolly-mammoths/ Tue, 13 May 2025 19:32:54 +0000 https://wyss.harvard.edu/?post_type=media_post&p=42730 What if aging was optional—and extinction reversible? In this episode of Ignition Sequence, Wyss Core Faculty member and geneticist and biotech pioneer, George Church, Ph.D., joins host Dylan Bohbot to explore the frontiers of gene therapy, de-extinction, and the future of human health. A founding scientist behind the Human Genome Project, and co-founder of Colossal Biosciences and Rejuvenate Bio…

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]]> https://wyss.harvard.edu/media-post/the-end-of-aging-and-extinction-george-church-ph-d-on-longevity-dire-wolves-and-woolly-mammoths/ A pioneer in CRISPR gene-editing technology, Church has been instrumental in advancing genetic research with real-world applications, including breakthroughs in organ transplantation and gene therapies. Credit: Wyss Institute at Harvard University. https://wyss-prod.imgix.net/app/uploads/2017/01/10173821/George-Church-headshot-003.jpg?auto=format%2Ccompress&crop=faces%2Centropy&fit=crop&h=400&q=50&w=300&s=42dbf81c80ac72016e94e4a85275457c"/> Wyss Institute launches Healthy Aging Fund with a gift from The Colossal Foundation https://wyss.harvard.edu/news/wyss-institute-launches-healthy-aging-fund-with-a-gift-from-the-colossal-foundation/ Thu, 30 Jan 2025 15:55:59 +0000 https://wyss.harvard.edu/?p=41970 The Healthy Aging Fund will explore the intricate connection between human and planetary health, aiming to unlock the secrets of aging and extend lifespans By Alexandra Jirstrand (BOSTON, MA and DALLAS, TX) – The Wyss Institute for Biologically Inspired Engineering at Harvard University is proud to announce the establishment of the Healthy Aging Fund, a transformative initiative aimed at unlocking the mysteries of aging. The Colossal Foundation has contributed $1.5 million to the Wyss Institute to launch this pioneering Fund…

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]]> https://wyss.harvard.edu/news/wyss-institute-launches-healthy-aging-fund-with-a-gift-from-the-colossal-foundation/ Credit: Envato Elements/ YuriArcursPeopleimages https://wyss-prod.imgix.net/app/uploads/2025/01/27083744/love-is-all-they-need-2024-08-22-20-11-23-utc-scaled.jpg?auto=format%2Ccompress&crop=faces%2Centropy&fit=crop&h=400&q=50&w=300&s=cefa23e0582ba5868780e71f328a19b8"/> Li Li on Bringing Advanced Omics Technology to Dermatology https://wyss.harvard.edu/news/humans-of-the-wyss-li-li-on-bringing-advanced-omics-technology-to-dermatology/ Tue, 28 Jan 2025 16:31:14 +0000 https://wyss.harvard.edu/?p=41908 The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and beyond. Whether she’s designing new clothes or creating and validating new therapeutics for inflammatory skin disorders and hair loss, Li Li is doing her best to help people regain their self…

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]]> https://wyss.harvard.edu/news/humans-of-the-wyss-li-li-on-bringing-advanced-omics-technology-to-dermatology/ Credit: Wyss Institute at Harvard University https://wyss-prod.imgix.net/app/uploads/2025/01/27131850/HoW-Lily-Li-05153-scaled.jpg?auto=format%2Ccompress&crop=faces%2Centropy&fit=crop&h=400&q=50&w=300&s=bec582bd36ecb65d12af5c2c48155e6d"/> Human Skin Rejuvenation: Li Li, Ph.D. https://wyss.harvard.edu/media-post/human-skin-rejuvenation-li-li-ph-d/ Mon, 27 Jan 2025 18:36:51 +0000 https://wyss.harvard.edu/?post_type=media_post&p=41815 In this episode of Conquer Aging or Die Trying, host Michael Lustgarten, Ph.D. speaks to Wyss Postdoctoral Fellow Li Li, Ph.D. about the technology she’s developing for skin rejuvenation. …

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]]> https://wyss.harvard.edu/media-post/human-skin-rejuvenation-li-li-ph-d/ Credit: Wyss Institute at Harvard University https://wyss-prod.imgix.net/app/uploads/2025/01/27131850/HoW-Lily-Li-05153-scaled.jpg?auto=format%2Ccompress&crop=faces%2Centropy&fit=crop&h=400&q=50&w=300&s=bec582bd36ecb65d12af5c2c48155e6d"/>