Wyss InstituteComputer Science – Wyss Institute

Russell Gould on using data to solve problems

Jessica Leff — Tue, 27 Jan 2026 13:45:43 +0000

The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and beyond. Russell Gould wants to know why. Seeking a flexible, open career path after serving in the military, he gravitated toward science, where he was encouraged to ask questions about the unknown.

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Forging a novel therapeutic path for patients with Rett Syndrome using AI

Jessica Leff — Wed, 02 Jul 2025 13:55:03 +0000

By Benjamin Boettner (BOSTON) — Rett syndrome is a devastating, rare genetic childhood disorder primarily affecting girls. Merely 1 out of 10,000 girls are born with it, and much fewer boys. It is caused by mutations in the MeCP2 gene on the X chromosome, leading to a spectrum of cognitive and physical impairments, including repetitive hand motions, speech difficulties, and seizures. However…

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Beyond Animals: Revolutionizing Drug Discovery with Human-Relevant Models

Jessica Leff — Wed, 02 Apr 2025 12:55:09 +0000

Code to Cure is a newsletter co-hosted by the Wyss Institute at Harvard University and Milad Alucozai on the intersection of AI, biology, and healthcare transforming medicine. By Milad Alucozai, Abishek Kulshreshtha, Megan Sperry, and Klaus Romero The average new drug requires over 15 years and $2 billion in funding to traverse the journey from discovery to full approval.

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From Data to Drugs: The Role of Artificial Intelligence in Drug Discovery

Jessica Leff — Thu, 09 Jan 2025 14:00:56 +0000

Code to Cure is a newsletter co-hosted by the Wyss Institute at Harvard University and Milad Alucozai on the intersection of AI, biology, and healthcare transforming medicine. By Milad Alucozai, Will Fondrie, and Megan Sperry Traditional drug discovery is slow, expensive, and prone to high clinical failure rates due to poor safety profiles, lack of efficacy, or both. Developing a new drug…

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From Bits to Biology: A New Era of Biological Renaissance powered by AI

Jessica Leff — Tue, 08 Oct 2024 13:00:59 +0000

Code to Cure is a newsletter co-hosted by the Wyss Institute at Harvard University and Milad Alucozai on the intersection of AI, biology, and healthcare transforming medicine. By Milad Alucozai Imagine a world where algorithms predict the next pandemic before it strikes, where you receive custom-designed treatments tailored to your individual genetic makeup, lifestyle, and medical history…

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Wyss Institute and Dr. Milad Alucozai Launch “Code to Cure” Newsletter

Jessica Leff — Tue, 17 Sep 2024 20:30:32 +0000

(BOSTON) – The Wyss Institute at Harvard University, along with Milad Alucozai, MSc, MPH, DrPH, is excited to announce the launch of the “Code to Cure” newsletter. Co-hosted by Alucozai and the Wyss Institute, this series will explore the convergence of artificial intelligence (AI), biology, and healthcare, highlighting the technologies and innovations shaping the future of human and planetary…

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AminoX: Making Better Protein Drugs, Quicker and Cheaper

Jessica Leff — Wed, 10 Jul 2024 13:56:00 +0000

A synthetic biology and advanced chemistry platform that efficiently incorporates non-standard amino acids by hacking the ubiquitous protein synthesis process. Credit: Wyss Institute at Harvard University…

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AminoX: Making Better Protein Drugs, Quicker and Cheaper

Jessica Leff — Wed, 01 May 2024 15:40:43 +0000

Protein drugs often offer the most effective way to treat a variety of medical illnesses and conditions. However, many proteins in their naturally occurring forms make poor drugs – they can cause toxicities that force patients to discontinue treatment, and they often have such short half-lives that patients would need to receive a constant infusion of them to see a therapeutic effect. Recently…

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Using AI, researchers identify a new class of antibiotic candidates

Jessica Leff — Wed, 20 Dec 2023 15:55:21 +0000

By Anne Trafton, MIT News Office Using a type of artificial intelligence known as deep learning, researchers at the Wyss Institute and MIT have discovered a class of compounds that can kill a drug-resistant bacterium that causes more than 10,000 deaths in the United States every year. In a study appearing today in Nature, the researchers showed that these compounds could kill methicillin…

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Coming together to engineer new treatments for serious diseases

Jessica Leff — Mon, 23 Oct 2023 17:14:48 +0000

By Jessica Leff Immunotherapy is often seen as the next frontier in cancer treatment, offering many benefits over traditional therapies like radiation and chemotherapy. Unfortunately, immunotherapy patients frequently experience painful side effects because antibodies affect healthy tissues along with the tumor. What if these drugs could more accurately target cancer cells…

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