Wyss InstituteGenetics – Wyss Institute

Reversing age by reprogramming gene expression networks

Jessica Leff — Wed, 14 Oct 2026 14:55:28 +0000

By Benjamin Boettner (BOSTON) — Every organ and tissue progressively loses function and integrity as it ages. In fact, researchers have identified “hallmarks of aging” that not only present specific processes impacted by age, but are also thought of as levers that, if successfully targeted, could help turn back the aging clock and result in tissue rejuvenation. In 2006…

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Pulling carbon into seawater using engineered bacteria

Jessica Leff — Fri, 28 Aug 2026 09:00:14 +0000

By Benjamin Boettner (BOSTON) — Rock weathering, the breakdown and dissolving of rocks and minerals caused by their exposure to water, air, and biological life, is a major regulator of Earth’s atmospheric CO2 levels and climate. Throughout Earth’s history, rock weathering has been faster during warm periods with increased atmospheric CO2 levels. Dissolved minerals ultimately wash into the…

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Researchers clear major obstacle in genetic engineering of proteins

Jessica Leff — Wed, 26 Aug 2026 15:13:59 +0000

By STEPHANIE DUTCHEN / Harvard Medical School Communications (BOSTON) — Scientists have been hard at work for more than 20 years to instruct biological systems, such as E. coli cells, to produce proteins they don’t naturally do. Success could mean faster, cheaper, innovative solutions for medicine, agriculture, materials science, environmental remediation, and other industries.

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Machine-learning how to overcome antibiotic-resistant gonorrhea

Jessica Leff — Wed, 17 Jun 2026 17:55:26 +0000

By Benjamin Boettner (BOSTON) — With tens of millions of annual cases, gonorrhea is the second most frequently reported sexually transmitted infection (STI). In the U.S. alone, over 600,000 cases are reported each year. If left untreated, gonorrhea can result in severe reproductive health issues, including infertility in both women and men, and pelvic inflammatory disease.

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Decoding inflammatory bowel disease – on a chip

Jessica Leff — Thu, 21 May 2026 09:30:43 +0000

By Benjamin Boettner (BOSTON) — Inflammatory bowel disease (IBD), which comprises the inflammatory conditions Crohn’s disease and ulcerative colitis, affects about 1.6 million Americans, many of whom cannot be effectively treated. This is mostly due to a lack of understanding of what exactly causes the increased inflammation, fibrosis, and compromised intestinal barrier that underlie this…

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Materializing safe, on-demand living therapeutics

Jessica Leff — Thu, 14 May 2026 17:55:55 +0000

By Benjamin Boettner (BOSTON) — Patient recovery from many debilitating conditions and diseases could be sped up significantly and be more effective if drugs and therapeutic molecules were delivered right to where they are needed in the body, over the entire regenerative process, and in doses finely tuned to therapeutic needs. An intriguing way to achieve this is the use of implantable…

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Cure ALD – Behind the Research | Alex LeNail – Safer Gene Therapy

Jessica Leff — Mon, 20 Apr 2026 15:26:58 +0000

Learn about Wyss Postdoctoral Fellow Alex LeNail‘s background and how he plans to develop a safer gene therapy for ALD (adrenoleukodystrophy) patients. If successful, this could go to clinical trials and give families hope for a cure. This video series tells the story of the scientists behind the breakthroughs, and why community-driven fundraising is the engine behind their discoveries. …

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Toward autonomous self-organizing biological robots with a nervous system

Mariel Schoen — Mon, 16 Mar 2026 18:30:42 +0000

By Benjamin Boettner (BOSTON) — Biobots, whose growing line of variants started with Xenobots, are fascinating tiny self-powered living robots built exclusively using frog embryonic cells. Originally developed in the laboratories of Wyss Institute Associate Faculty member and Tufts University Professor Michael Levin, Ph.D. and his collaborators at University of Vermont…

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Wyss Institute appoints three new Associate Faculty members: Ahmad Khalil, Jarad Mason, and Ting Wu

Jessica Leff — Mon, 08 Dec 2025 14:50:20 +0000

By Jessica Leff The Wyss Institute is proud to welcome three new Associate Faculty members: Ahmad (Mo) Khalil, Ph.D., Jarad Mason, Ph.D., and Chao-ting (Ting) Wu, Ph.D. Each has a history of collaborating with the Institute’s researchers. Their diverse expertise and fresh perspectives will further strengthen the Wyss’ innovative and collaborative ecosystem and enable pioneering advances in…

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How federal funds fuel life-saving innovation

Jessica Leff — Thu, 20 Nov 2025 17:49:40 +0000

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