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Intern – Biostasis/Circavent Co-op Position

About the Wyss:

The mission of the Wyss Institute for Biologically Inspired Engineering at Harvard University is to transform human healthcare and the environment by emulating the way nature builds. Developed as an alliance between Harvard and other premier academic and clinical partner institutions, Institute faculty and staff collaborate in high-risk, fundamental research and science-driven technology development. A major focus of the Institute is to translate the technologies developed by its faculty and staff into commercial products and therapies through collaborations with clinical investigators and establishment of corporate alliances. For more information, discover our technologiescatch up on our recent news, or watch our latest videos.

Role Description:

The Wyss Institute for Biologically Inspired Engineering at Harvard University invites applications for a Bioengineering Co-op student position in the Synthetic Biology and the Bioinspired Therapeutics and Diagnostics platforms. The mission of the Wyss Institute is to discover the engineering principles that Nature uses to build living things; to pursue the high-risk research that is fundamental to advance this effort; and to harness these insights to create biologically-inspired materials and devices to revolutionize clinical medicine and create a more sustainable world.

The candidate will work within a multidisciplinary team, supporting the discovery of therapeutics for neurological and psychiatric disorders, in particular bipolar disorder, and for safely inducing biostasis. The project uses a unique screening combination of Xenopus frog embryo and tadpole models and cerebral organoids derived from human induced pluripotent stem cells. The candidate will perform phenotypic screens and behavioral analysis using an automated custom instrumentation for assessing movement patterns in tadpoles. Primary responsibilities include embryo and tadpole culture, Xenopus husbandry, behavioral/cognitive assays, and light and fluorescence microscopy. The candidate will design and execute experiments, analyze experimental data, and communicate their findings to their peers and advisors in formal and informal settings.

The candidate will report to a senior staff scientist at the Wyss Institute and can expect rigorous training, exposure to multiple disciplines and in-depth learning about therapeutics, preparing them for pursuing academic and pharmaceutical careers.

Principal Duties and Responsibilities include the following: (Other duties may be assigned)

  • Design and carry out experiments using the existing protocols and high-throughput instrumentation developed in the lab.
  • Provide daily care for Xenopus embryos and tadpoles in our dedicated Xenopus facility, including media changes, feeding, and health checks.
  • Light and fluorescence microscopy of Xenopus embryos and tadpoles.
  • Analysis, interpretation, and presentation of various type of phenotypic data.
  • Order supplies/consumables and maintain shared stocks.
  • Accurately and thoroughly document experimental observations and protocols and write/update standard operating procedures.
  • Under the supervision of senior staff, present data and conclusions at meetings within the Wyss Institute.

What you’ll need:

  • Knowledge/Skill: Senior undergraduate level biology/biochemistry.
  • Some experience with live animals would be advantageous.
  • Applicant should be willing and able to work without daily supervision. T
  • This position requires someone detail oriented and interested in problem solving.
  • Basic communication (written & verbal), organization (shared electronic lab notebook), and computer skills (Microsoft Office) are a must.

Where You Can Apply:

Applications should be sent to faculty_postdocs@wyss.harvard.edu using the subject line “Biostasis-Circavent CO-OP Position.”

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Harvard University is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law. Demonstrates a commitment to diversity, inclusion, and cultural awareness through actions, interactions, and communications with others.

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