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Postdoctoral Fellow Research Opening — Modeling Bone Marrow Diseases and Therapeutic Responses in Human Organ Chips

The Wyss Institute for Biologically Inspired Engineering at Harvard University invites applications for a postdoctoral fellow position in the Biotherapeutics and Diagnostics platform. The mission of the Wyss Institute is to discover the engineering principles that Nature uses to build living things; to pursue the high-risk research that is fundamental to advance this effort; and to harness these insights to create biologically-inspired technological innovations to advance human health and improve the environment – thereby revolutionizing clinical medicine and creating a more sustainable world.

We seek outstanding postdoctoral applicants with expertise and knowledge of bone marrow function, the hemapoietic niche, immunology and stem cell biology to join an interdisciplinary team of biologists and engineers. We are focused on using human organ-on-a-chip (Organ Chip) microfluidic culture devices we have created to study and model human bone marrow diseases, including acute radiation syndrome, genetic diseases (e.g., Shwachman-Diamond Syndrome) and sickle cell disease. Applicants are expected to hold a Ph.D. or M.D. and have a proven record of high quality publications in bone marrow function and hematopoiesis. Strong interest in contributing to multidisciplinary teams (engineers, biologists/physiologists, clinicians) is critical for this position. Expertise in in vitro culture and characterization of cells derived from human bone marrow and cord blood, as well as strong knowledge of flow cytometry and basic molecular and cell biology concepts and techniques is a must.

The ideal candidate would bring expertise in bone marrow biology, function, and disease, with an interest in applying this expertise in combination with modern bioengineering practices. This postdoctoral fellow is expected to develop and lead an interdisciplinary research project aimed at creating microengineered Organ Chip models, simulating human diseases, and exploring their use in drug discovery applications.

Applications, assembled as single PDF files, should contain a complete resume, cover letter describing research interests and goals, full list of publications, copies of up to three relevant scientific papers, as well as the names and contact information of three references (expected to provide letters of recommendation). Applications should be sent to using the subject line “BONE MARROW APPLICATION.”

Harvard University is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy, and pregnancy-related conditions, or any other characteristic protected by law. Demonstrates a commitment to diversity, inclusion, and cultural awareness through actions, interactions, and communications with others.

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