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Testing Gene Editing Therapies Against Viral Infection in a Human Lung-on-a-Chip – Postdoctoral Fellow

The Wyss Institute for Biologically Inspired Engineering at Harvard University invites applications for a postdoctoral fellow position in the Bioinspired Therapeutics & Diagnostics Platform. The mission of the Wyss Institute is to discover the engineering principles that Nature uses to build living things; to pursue the high-risk research that is fundamental to advance this effort; and to harness these insights to create biologically-inspired materials and devices to advance human health and improve the environment – thereby revolutionizing clinical medicine and creating a more sustainable world.

We seek outstanding postdoctoral applicants with expertise and knowledge of virology and lung biology to join an interdisciplinary team of biologists and engineers for the development of novel in vitro human “organ-on-chip” microsystems technologies to study and model respiratory viral infection and propagation in vitro. Applicants are expected to hold a Ph.D. and/or M.D. and have a proven record of high-quality publications in the field of viral infection and/or lung biology or physiology. Previous experience in gene editing technologies of the lung, such as CRISPR is a plus.

Strong interest in contributing to multidisciplinary teams (engineers, biologists/physiologists, clinicians) is critical for this position. Expertise in working with influenza and/or corona virus, in vitro culture, inflammatory responses, and characterization of cells derived from the lung (small airway/alveolus), as well as knowledge of gene editing techniques, flow cytometry, basic molecular and cell biology concepts and techniques is a must.

The ideal candidate would bring expertise in respiratory viral infection and gene editing therapies, as well as lung biology, function, and inflammatory responses, with an interest in applying this expertise in combination with modern bioengineering practices by leveraging human organ-on-a-chip technology in vitro. This postdoctoral fellow is expected to develop and lead an interdisciplinary research project aimed at using microengineered “organ-on-chip” models, to simulate respiratory viral infection, and exploring their use in drug discovery applications.

Applications, assembled as single PDF files, should contain a complete resume, cover letter describing research interests and goals, full list of publications, copies of up to three relevant scientific papers, as well as the names and contact information of three references (expected to provide letters of recommendation). Applications should be sent to faculty_postdocs@wyss.harvard.edu using the subject line “LUNG VIRUS INFECTION ON CHIP- POSTDOCTORAL FELLOW APPLICATION.”

Harvard University is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law.

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