Wyss InstituteSearch Results for “lindsay brownell” – Wyss Institute https://wyss.harvard.edu Wyss Institute at Harvard Mon, 13 Apr 2026 21:52:23 +0000 en-US hourly 1 https://wordpress.org/?v=6.7.1 ENTERing a new era of drug delivery https://wyss.harvard.edu/news/entering-a-new-era-of-drug-delivery/ Thu, 15 May 2025 13:25:50 +0000 https://wyss.harvard.edu/?p=42721 Protein-based nanoparticles can effectively deliver DNA, RNA, proteins, and gene editors directly into multiple cell types while avoiding toxicity By Lindsay Brownell (BOSTON) — Getting medicines into the cells they’re designed to treat is a perennial problem for the medicine and pharmaceutical industries, and patients often suffer from side effects and ineffective treatments as a result. Current drug delivery vehicles carry a host of risks and limits: lipid nanoparticles can cause immune reactions and accumulate in the liver…

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]]> https://wyss.harvard.edu/news/entering-a-new-era-of-drug-delivery/ This microscopy image shows the ENTER constructs, composed of spheres of ELPs containing EEPs inside. Credit: Wyss Institute at Harvard University https://wyss-prod.imgix.net/app/uploads/2025/05/13151412/Fig-1i-colorized.jpg?auto=format%2Ccompress&crop=faces%2Centropy&fit=crop&h=400&q=50&w=300&s=a7cce4c59204f3b724270a0925e502a4"/> Newly discovered cyanobacteria could help sequester carbon from oceans and factories https://wyss.harvard.edu/news/newly-discovered-cyanobacteria-could-help-sequester-carbon-from-oceans-and-factories/ Tue, 29 Oct 2024 12:58:56 +0000 https://wyss.harvard.edu/?p=41293 Strains specialized to live in high-CO2 oceanic environments have evolved traits that are useful for decarbonization and bioproduction By Lindsay Brownell (BOSTON) — An international coalition of researchers from the United States and Italy has discovered a novel strain of cyanobacteria, or algae, isolated from volcanic ocean vents that is especially adept at growing rapidly in the presence of CO2 and readily sinks in water, making it a prime candidate for biologically-based carbon sequestration projects and bioproduction of…

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]]> https://wyss.harvard.edu/news/newly-discovered-cyanobacteria-could-help-sequester-carbon-from-oceans-and-factories/ https://wyss-prod.imgix.net/app/uploads/2024/10/28110113/Marine-Cyanobacteria_Listing-Image.jpg?auto=format%2Ccompress&crop=faces%2Centropy&fit=crop&h=400&q=50&w=300&s=484c59606b52d430fdda1ca1ab4a6ae4"/> Kwasi Adu-Berchie named 2024 STAT Wunderkind https://wyss.harvard.edu/news/kwasi-adu-berchie-named-2024-stat-wunderkind/ Wed, 16 Oct 2024 14:11:12 +0000 https://wyss.harvard.edu/?p=41197 The honor is bestowed annually on the next generation of scientific superstars By Lindsay Brownell (BOSTON) – The Wyss Institute is thrilled to announce that Kwasi Adu-Berchie, Ph.D., a member of the Wyss’ Advanced Technology Team working in Immuno-Materials Platform led by Core Faculty member Dave Mooney, Ph.D., has been named a 2024 STAT Wunderkind by STAT News. The Wunderkinds awards are given annually by STAT News to the next generation of scientific superstars who…

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]]> https://wyss.harvard.edu/news/kwasi-adu-berchie-named-2024-stat-wunderkind/ Kwasi Adu-Berchie https://wyss-prod.imgix.net/app/uploads/2022/08/10092956/Kwasi-Adu-Berchie-3.jpg?auto=format%2Ccompress&crop=faces%2Centropy&fit=crop&h=400&q=50&w=300&s=ac2afd50b3022ac1f31a985049490116"/> Preventing pollution with bioinspired solutions https://wyss.harvard.edu/news/preventing-pollution-with-bioinspired-solutions/ Tue, 17 Sep 2024 21:14:47 +0000 https://wyss.harvard.edu/?p=41014 Three Wyss projects aim to reduce global pollution through better detection, greener alternatives, and creating value from waste By Lindsay Brownell In honor of Pollution Prevention Week, we’re highlighting three Wyss projects that are taking on the formidable problems of PFAS and plastic – persistent and toxic pollutants that threaten the health of humans, animals, and ecosystems. Per- and polyfluoroalkyl substances (PFAS), or “forever chemicals,” are toxic substances that increase the risk of many health…

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]]> https://wyss.harvard.edu/news/preventing-pollution-with-bioinspired-solutions/ Caption https://wyss-prod.imgix.net/app/uploads/2024/09/17121336/top-view-of-globe-in-plastic-bag-with-garbage-arou-2023-11-27-05-24-14-utc.jpg?auto=format%2Ccompress&crop=faces%2Centropy&fit=crop&h=400&q=50&w=300&s=e8e6d4e447e561550ddbb3f45c0691d6"/> Ropirio launches from Wyss Institute to develop first-in-class lymphatic medicines https://wyss.harvard.edu/news/ropirio-launches-from-wyss-institute-to-develop-first-in-class-lymphatic-medicines/ Wed, 11 Sep 2024 13:55:12 +0000 https://wyss.harvard.edu/?p=40940 The company is leveraging a discovery program developed at Harvard and Boston University to treat a wide range of serious diseases By Lindsay Brownell (BOSTON) — The Wyss Institute at Harvard University announced today that Ropirio Therapeutics, Inc. (Ropirio) has secured a worldwide, exclusive license from Harvard’s Office of Technology Development (OTD) and Boston University (BU)’s Technology Development office for novel molecules that activate the lymphatic system – a first in the pharma industry. “There has been a…

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]]> https://wyss.harvard.edu/news/ropirio-launches-from-wyss-institute-to-develop-first-in-class-lymphatic-medicines/ The human body's lymphatic system is a critical network that allows proper functioning of the immune system and movement of fluids, but it can become impaired due to inflammation. Ropirio is developing novel medicines that directly target the lymph vessels to treat a number of diseases. Credit: Envato Elements https://wyss-prod.imgix.net/app/uploads/2024/09/09161236/doctor-checking-size-of-lymph-nodes-2023-11-27-05-27-54-utc.jpg?auto=format%2Ccompress&crop=faces%2Centropy&fit=crop&h=400&q=50&w=300&s=46a754da4f0fc9608020f78c3b9ca7c0"/> Alzheimer’s drug may someday help save lives by inducing a state of “suspended animation” https://wyss.harvard.edu/news/alzheimers-drug-may-someday-help-save-lives-by-inducing-a-state-of-suspended-animation/ Thu, 22 Aug 2024 15:25:07 +0000 https://wyss.harvard.edu/?p=40410 New research in tadpoles reveals that FDA-approved donepezil puts the animals in reversible torpor-like state By Lindsay Brownell (BOSTON) — Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University report that they were able to successfully put tadpoles of Xenopus laevis frogs into a hibernation-like torpor state using donepezil (DNP), a drug approved by the FDA to treat Alzheimer’s. The team had previously used another drug, SNC80, to achieve similar results in…

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]]> https://wyss.harvard.edu/news/alzheimers-drug-may-someday-help-save-lives-by-inducing-a-state-of-suspended-animation/ https://wyss-prod.imgix.net/app/uploads/2022/09/26143549/Unravel-Biosciences_Tadpole_crop-e1664217399832.jpeg?auto=format%2Ccompress&crop=faces%2Centropy&fit=crop&h=400&q=50&w=300&s=7d56efb3445c760e1ffa42422e0ede9b"/> 3D-printed blood vessels bring artificial organs closer to reality https://wyss.harvard.edu/news/3d-printed-blood-vessels-bring-artificial-organs-closer-to-reality/ Wed, 07 Aug 2024 16:55:18 +0000 https://wyss.harvard.edu/?p=40723 New printing method creates branching vessels in heart tissue that replicate the structure of human vasculature in vitro By Lindsay Brownell (BOSTON) — Growing functional human organs outside the body is a long-sought “holy grail” of organ transplantation medicine that remains elusive. New research from Harvard’s Wyss Institute for Biologically Inspired Engineering and John A. Paulson School of Engineering and Applied Science (SEAS) brings that quest one big step closer to completion. A team of scientists…

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]]> https://wyss.harvard.edu/news/3d-printed-blood-vessels-bring-artificial-organs-closer-to-reality/ A new technique that builds on SWIFT, called co-SWIFT, creates branched vascular channels to more accurately replicate the structure of naturally occurring blood vessels. Credit: Wyss Institute at Harvard University https://wyss-prod.imgix.net/app/uploads/2024/08/06114145/printedVesselNetwork.jpg?auto=format%2Ccompress&crop=faces%2Centropy&fit=crop&h=400&q=50&w=300&s=7173ce2b2a4331486f7f369e3d6db95a"/> A better way to make RNA drugs https://wyss.harvard.edu/news/a-better-way-to-make-rna-drugs/ Fri, 12 Jul 2024 09:00:40 +0000 https://wyss.harvard.edu/?p=39895 New enzymatic synthesis method developed at Wyss Institute expands RNA therapeutic capabilities while eliminating toxic byproducts of standard chemical synthesis By Lindsay Brownell (BOSTON) — While the COVID-19 vaccines introduced many people to RNA-based medicines, oligonucleotides have already been on the market for years to treat diseases like Duchenne Muscular Dystrophy and amyloidosis. RNA therapies offer many advantages over traditional small molecule drugs, including their ability to address almost any genetic component within cells and to guide…

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]]> https://wyss.harvard.edu/news/a-better-way-to-make-rna-drugs/ Single-stranded RNA is a valuable basis for new drugs, but chemically synthesizing it is costly and damaging to the environment. A new enzymatic RNA synthesis method developed at the Wyss offers a better solution. Credit: Shutterstock https://wyss-prod.imgix.net/app/uploads/2019/10/10142259/RNA_shutterstock_1203487687.jpg?auto=format%2Ccompress&crop=faces%2Centropy&fit=crop&h=400&q=50&w=300&s=0613166f27afc218df6f5594b6627cea"/> Circe Bioscience licenses technology to decarbonize industry with microbes developed at Wyss Institute at Harvard University https://wyss.harvard.edu/news/circe-bioscience-licenses-technology-to-decarbonize-industry-with-microbes-developed-at-wyss-institute-at-harvard-university/ Wed, 15 May 2024 10:55:37 +0000 https://wyss.harvard.edu/?p=39951 Novel gas fermentation approach enables engineered microbes to eat greenhouse gases and produce valuable products for multiple uses By Lindsay Brownell (BOSTON) — The Wyss Institute for Biologically Inspired Engineering at Harvard University announced today that Circe, a startup developed at the Institute and spun out of Harvard, has signed a worldwide, exclusive licensing agreement coordinated by Harvard’s Office of Technology Development (OTD) to commercialize a novel bioproduction technology that could significantly…

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]]> https://wyss.harvard.edu/news/circe-bioscience-licenses-technology-to-decarbonize-industry-with-microbes-developed-at-wyss-institute-at-harvard-university/ Circe has used its gas fermentation technology to make cocoa butter from microbes, which can be incorporated into chocolate truffles and other foods. Credit: Wyss Institute at Harvard University https://wyss-prod.imgix.net/app/uploads/2024/05/10124305/2024.03.14-Reimagining-Sustainability-06508.jpg?auto=format%2Ccompress&crop=faces%2Centropy&fit=crop&h=400&q=50&w=300&s=8c9d1f19969e8b32d6da38639eb93c33"/> Solving Sustainability with Synthetic Biology https://wyss.harvard.edu/news/solving-sustainability-with-synthetic-biology/ Thu, 25 Apr 2024 12:58:58 +0000 https://wyss.harvard.edu/?p=39761 How harnessing the power of microbes could save us all By Lindsay Brownell As humans, we like to think that we are the smartest animals on planet Earth. After all, no other species has invented smartphones, heat pumps, or jet engines. But for all our innovations, we have also created problems on a global scale. Take plastic, for example. Humans invented plastic scarcely more than a century ago, but we now produce more than 350 million…

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