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Howon Lee, Ph.D.

Engineer II

Howon Lee, Ph.D.

Howon is currently a Staff Engineer at the Wyss Institute for Biologically Inspired Engineering and a former Postdoctoral Fellow at Dr. George Church’s lab at Harvard Medical School. He has a solid academic background in electrical engineering and extensive research practice in multi-disciplinary fields including molecular biology, photonics, microfluidics, polymer science, and computer and mechanical engineering.  He has been working on developing novel devices for oligonucleotide purification, detection, and synthesis. During his tenure as Postdoctoral Fellow, Howon invented a device for photon-directed multiplexed enzymatic oligonucleotide synthesis for DNA data storage which could encode a theme song of Super Mario to the DNA. Prior to joining Wyss Institute, Howon developed Color-barcoded magnetic microparticles for multiplexed bioassays which resulted in the creation of Quanta Matrix. Howon also developed an approach called Sniper cloning: A high-throughput optomechanical retrieval method for sequence-verified clonal DNA. This work is now commercialized by Celemics for the development of high-sensitivity cancer gene detection panels and de novo gene assembly. Currently, He is actively working on an enzymatic RNA synthesis project. Howon earned his Ph.D. in Electrical Engineering from Seoul National University. Received his Bachelor’s and Master’s Degree in Electrical and Computer Engineering from Seoul National University.

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