Richie uses his expertise in synthetic, polymer, and biomaterials chemistry to solve problems in biology. His major interests include technology to stimulate, record from, and study the nervous system as well as nucleic acid synthesis, sequencing, and nanotechnology. Before joining the Wyss, Richie worked as a Group Leader at the startup company Expansion Technologies, Inc. where he brought to market techniques and reagents for high resolution imaging of biological samples. He received his Ph.D. in chemistry from the University of Illinois Urbana-Champaign where he synthesized complex, organic nanostructures for controlled release applications. As a postdoctoral fellow in the Department of Biomedical Engineering at Boston University and an affiliate of the MIT Media Lab, he developed surgical methods to deliver large molecules to the brain and created neurotransmitter-releasing DNA nanostructures.