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Ting (C.-ting) Wu, Ph.D.

Associate Faculty

Ting Wu is a Professor of Genetics at Harvard Medical School, Director of the Consortium for Space Genetics, and Director of the Personal Genetics Education Project (pgEd). She is the recipient of an NIH Director’s 2012 Pioneer Award for her laboratory’s work on genome organization, homolog pairing, and inheritance, and an NIH Director’s 2016 Transformative Research Award for work on sequence ultraconservation as a strategy for maintaining genome integrity. She is also a co-investigator on a Center of Excellence Award. As part of these efforts, her group has developed a variety of technologies, ranging from strategies that facilitate genome engineering to those that enable high-throughput screening of entire genomes using fluorescent in situ hybridization (Hi-FISH). She and her co-workers also invented the Oligopaints method for in situ visualization of DNA and RNA, including distinguishing maternal from paternal homologs using homolog-specific Oligopaints (HOPs). Most recently, her group has enabled in situ single-molecule super-resolution imaging of the genome via OligoSTORM and OligoDNA-PAINT, which reflect the combination of Oligopaints with the STORM (in collaboration with Xiaowei Zhuang) and DNA-PAINT (in collaboration with Ralf Jungmann and Peng Yin) technologies, respectively.

The Wu laboratory also houses pgEd, a nonprofit program which promotes public awareness and dialogue about genetics and genetic technologies across all communities through Congressional briefings, curricula and trainings for teachers, consultations with the film and television industry and, most recently, partnerships with communities of faith.

Wu received her B.A. from Harvard University in Biology and her Ph.D. from Harvard Medical School in Genetics. She briefly spent time at Stanford Medical School before completing her postdoctoral work at the Station for Natural Studies and Yale University. Wu was a fellow at the Massachusetts General Hospital in the Department of Molecular Biology from 1987 to 1991, then moved to Harvard Medical School’s main campus as an assistant professor, first in the Department of Anatomy and Cellular Biology and then in the Department of Genetics (1993). In 2005, she left the Department of Genetics to become a professor of pediatrics in the Division of Molecular Medicine at Boston Children’s Hospital. She returned to the Department of Genetics at Harvard Medical School as a full professor in 2007.

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