Wiegand has been a member of the Wyss research community since November 2013. After working in the industrial biotech sector developing methods to evaluate the performance of bioengineered dermal equivalents in chronic wound healing, he joined the Synthetic Biology Focus Area to support efforts in improving high-throughput oligonucleotide library synthesis, large-scale gene assembly, and in situ gene sequencing. Since then, Wiegand has been interested in applying his extensive experience in bioanalytical chemistry and assay development to tackle difficult problems in Synthetic Biology. Wiegand is currently working with George Church on engineering and screening enzymes for next-generation oligonucleotide synthesis as well as developing cell-free, in vitro transcription-translation systems for the discovery of genetically encoded small molecules. He received his Bachelor of Science in Biochemistry from Northeastern University in Boston, Massachusetts.