Josie received her B.S. in Computer Science from the California Institute of Technology (Caltech). In 2014, she joined Prof. Peng Yin’s laboratory as a graduate student to research molecular programming. She developed the Primer Exchange Reaction (PER) method for synthesizing single-stranded DNA and later worked with collaborators to apply PER for signal amplification in fluorescence in situ hybridization (FISH) and immunofluorescence (IF) assays. This method, Signal Amplification by Exchange Reaction (SABER), enables rapid multiplexed tissue imaging of genomic, transcriptomic, and proteomic molecular targets. As a Technology Development Fellow working in the Molecular Robotics focus area at the Wyss, she is continuing transformative molecular technology innovation in diverse fields including imaging, diagnostics, and data storage.