Wyss InstituteHeart Disease – Wyss Institute

Ellen Roche gets to the heart of the matter

Jessica Leff — Fri, 13 Feb 2026 16:19:10 +0000

By Jessica Leff There is no Wyss faculty member more qualified to discuss matters of the heart than Ellen Roche, Ph.D., who has been working on developing cardiac devices since she was an undergraduate student. During her Ph.D. work, which was co-advised by Wyss Faculty members David Mooney, Ph.D., and Conor Walsh, Ph.D., she innovated the epicardial delivery of bioagents to the heart…

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20-ish Questions with Christopher Chen

Jessica Leff — Fri, 06 Feb 2026 14:00:53 +0000

20-ish Questions shows a different side of Wyss Institute faculty, touching on aspects of their personal life, hobbies, interests, as well as their research. This round follows Christopher Chen, M.D., Ph.D., a Core Faculty member at the Wyss Institute. He is also the William Fairfield Warren Distinguished Professor, Biomedical Engineering & Director, Biological Design Center at Boston University.

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20-ish Questions with Ellen Roche

Jessica Leff — Fri, 21 Nov 2025 14:00:10 +0000

20-ish Questions shows a different side of Wyss Institute faculty, touching on aspects of their personal life, hobbies, interests, as well as their research. This round follows Ellen Roche, an Associate Faculty member of the Wyss Institute as well as the Latham Family Career Development Professor at the Department of Mechanical Engineering and the Institute for Medical Engineering and Science…

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The Wyss Institute’s 2025-2026 Validation Projects

Jessica Leff — Thu, 14 Aug 2025 15:00:53 +0000

Throughout recent years, the Wyss’ Validation Project mechanism has proven to be a highly valuable instrument for selecting and kick-starting projects with early potential for positive impact on healthcare and the environment. Reaching deep into areas with major unmet needs across the diverse Grand Challenges laid out by the Institute, the newly selected projects are driven by multi-talented teams…

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Blood Clot Dx

admin — Wed, 09 Jul 2025 17:00:40 +0000

Blood clots can arise anywhere in the body, blocking blood flow and causing pain and other symptoms. The most serious types of clots, called deep vein thrombosis (DVT), typically form in the veins in the legs, and can break off and become lodged in a lung. This can cause a pulmonary embolism (PE), which is when blood flow to the lungs is prevented and can be fatal. The symptoms of PE resemble…

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The Tipping Point for Women’s Health

Mariel Schoen — Mon, 23 Jun 2025 14:00:29 +0000

Last month, the Wyss Institute had the honor of hosting the Women’s Health Access Matters (WHAM) Spring Forum, convening researchers, industry leaders, investors, and advocates committed to closing the gender health gap. The event brought together cross-sector voices to explore bold ideas, share scientific breakthroughs, and catalyze action across women’s brain, heart, and reproductive health.

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Innovative tissue engineering: ESCAPE, a pioneering new method explained

Jessica Leff — Wed, 11 Dec 2024 16:00:31 +0000

By Boston University Communications (BOSTON) — When it comes to the human body, form and function work together. The shape and structure of our hands enable us to hold and manipulate things. Tiny air sacs in our lungs called alveoli allow for air exchange and help us breath in and out. And tree-like blood vessels branch throughout our body, delivering oxygen from our head to our toes.

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ESCAPE Bioengineering

Jessica Leff — Wed, 11 Dec 2024 16:00:06 +0000

A research team at the Wyss Institute and Boston University has developed ESCAPE, the first method that enables the engineering of tissues across multiple length scales, ranging from the diameter of a cell to the cm scale of a heart valve. Credit: Wyss Institute at Harvard University…

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CRISPR’s Impact, Today

Mariel Schoen — Mon, 21 Oct 2024 12:00:08 +0000

By Seth Kroll (BOSTON) — In the not-so-distant past, CRISPR, the revolutionary gene-editing technology, was discovered as a defense system protecting bacteria against viruses. Today, with the persistence and ingenuity of many scientists, it is no longer just the subject of fascinating academic research papers and speculative discussions on its future usefulness for medicine.

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Fiber-infused ink enables 3D-printed heart muscle to beat

Jessica Leff — Tue, 08 Aug 2023 14:30:44 +0000

By Kat J. McAlpine / SEAS Communications (BOSTON) – Over the last decade, advances in 3D printing have unlocked new possibilities for bioengineers to build heart tissues and structures. Their goals include creating better in vitro platforms for discovering new therapeutics for heart disease, the leading cause of death in the United States, responsible for about one in every five deaths…

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