Wyss InstituteHemostasis – Wyss Institute

Blood Clot Dx

admin — Wed, 09 Jul 2025 17:00:40 +0000

Blood clots can arise anywhere in the body, blocking blood flow and causing pain and other symptoms. The most serious types of clots, called deep vein thrombosis (DVT), typically form in the veins in the legs, and can break off and become lodged in a lung. This can cause a pulmonary embolism (PE), which is when blood flow to the lungs is prevented and can be fatal. The symptoms of PE resemble…

Source

Reimagining a World Without Terminal Illness

Jessica Leff — Mon, 16 Jun 2025 15:00:52 +0000

As he battles metastatic skin cancer, Wyss Scientific Instrument maker John Caramanica is more motivated than ever to do his part in fabricating technologies to improve the health of others and our planet. Credit: Wyss Institute at Harvard University…

Source

Reimagining the World Without Terminal Illness: John Caramanica

Jessica Leff — Mon, 16 Jun 2025 15:00:45 +0000

By Jessica Leff Before 5:30 AM, in the quiet stillness of the early morning, John Caramanica enters the Wyss machine shop. He turns on the devices, and while he waits for them to warm up, he proceeds one floor up to the kitchen to turn on the kettle. Once he has his tea, he sips it while sitting in the Wyss entryway, staring at the large screen, taking in news from across the Institute.

Source

Portable, injectable clotting agent could treat trauma victims on the front lines

Jessica Leff — Fri, 31 Jul 2020 18:00:49 +0000

By Leah Burrows / SEAS Communications (CAMBRIDGE, Mass) — When it comes to traumatic injuries, it’s a race against time. A person with major hemorrhage can die from blood loss within minutes, so staunching the wound and getting them to a hospital as fast as possible is critical. Bleeding from the extremities can be slowed with compression but what about internal bleeding? In a hospital…

Source

Sticky when wet: strong adhesive for wound healing

Mariel Schoen — Thu, 27 Jul 2017 17:00:53 +0000

By Lindsay Brownell (CAMBRIDGE, Mass.) — Anyone who has ever tried to put on a Band-Aid® when their skin is damp knows that it can be frustrating. Wet skin isn’t the only challenge for medical adhesives – the human body is full of blood, serum, and other fluids that complicate the repair of numerous internal injuries. Many of the adhesive products used today are toxic to cells…

Source

Pulmonary Thrombosis-on-a-Chip provides new avenue for drug development

Mariel Schoen — Mon, 22 May 2017 22:45:20 +0000

By Lindsay Brownell (BOSTON) — The average human pair of lungs is permeated by a network of about 164 feet of blood vessels (roughly the width of a football field), including microscopic blood capillaries, which facilitate the diffusion of oxygen into the bloodstream in exchange for carbon dioxide. Damage to any of those vessels can cause a blood clot, or thrombus, to form, which can cause or…

Source

FDA to evaluate Organs-on-Chips

Lucy Thomas — Tue, 11 Apr 2017 21:00:26 +0000

Today the U.S. Food and Drug Administration (FDA) announced that it will be evaluating the organs-on-chips technology, originally developed at the Wyss Institute, towards identifying a more precise model for studying the effects of potential chemical and biological hazards found in foods, cosmetics or dietary supplements than is now available. The FDA will work with Emulate, Inc.

Source

Disruptive: Sports Genomics

Lucy Thomas — Tue, 21 Mar 2017 21:07:02 +0000

With 100 trillion cells in the human body, bacteria outnumber our own human cells 2 to 1. These bacteria make up one’s microbiome, and particularly bacteria in our guts affect all our key organ functions. They play a role in our health, development and wellness, including endurance, recovery and mental aptitude. In this episode of Disruptive, Wyss Core Faculty member George Church and Wyss…

Source

Controlling bleeding disorders with fitted hydrogel casts

Lucy Thomas — Wed, 16 Nov 2016 19:05:58 +0000

(BOSTON) — Small blood clots called emboli are mostly known for traveling through the vasculature before they lodge and obstruct vessels, impeding blood and oxygen supply to organs like the lung. To stop excessive bleeding or the flow of blood into an aneurysm, clinicians harness the same principle by forming artificial therapeutic emboli that can plug blood-carrying vessels.

Source

Shear-Thinning Biomaterial: Catheter Injection

Mariel Schoen — Tue, 08 Nov 2016 05:00:00 +0000

This movie shows the solid state of the shear-thinning biomaterial immediately after release from the catheter into an aqueous solution (00:04). The STB is cohesive and remains as one solid piece throughout the injection process. There is no noticeable dissolution of the STB into the solution, suggesting it is stable immediately after being discharged from the tip of the catheter (5F-Beacon Tip…

Source