Wyss InstituteRegenerative Medicine – Wyss Institute

Wyss Institute receives Massachusetts Life Science Center award to advance metabolomics and lipidomics research across Massachusetts ecosystem

Jessica Leff — Wed, 22 Jul 2026 14:03:23 +0000

By Benjamin Boettner (BOSTON) — The Wyss Institute at Harvard University has received an award from the Massachusetts Life Science Center (MLSC), enabling it to host a next-generation metabolomics and lipidomics analytical platform. The platform will allow its researchers to creatively pursue new approaches to biomarker and drug discovery across multiple health challenges the Institute is…

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Recapitulating intramuscular vaccination with mRNA vaccines in patient-specific Lymphoid Organ Chips

Mariel Schoen — Fri, 17 Jul 2026 13:55:40 +0000

By Benjamin Boettner (BOSTON) — The protective abilities of the Moderna and BioNTech mRNA vaccines developed against COVID-19 saved millions of lives during the pandemic and put this platform technology in the spotlight of vaccine research. By now, mRNA vaccines for other infectious diseases, such as influenza, RSV, and HIV are being tested in clinical trials and highly anticipated.

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TIB: Tolerance Inducing Biomaterials for Regulatory T Cells

Jessica Leff — Mon, 06 Jul 2026 17:38:18 +0000

Tissue regeneration following injuries and degenerative processes benefits greatly from the activity of regulatory T cells (Tregs) that help balance the immune system, which senses, regulates, and helps restore tissue environments following injury and in disease. In fact, immune therapies using Tregs have shown first promise in treating a wider variety of diseases. However…

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Multidisciplinary Wyss team receives 2026 Lush Prize Science Award

Jessica Leff — Mon, 18 May 2026 18:30:48 +0000

(BOSTON) — The Wyss Institute for Biologically Inspired Engineering at Harvard University is proud to announce that the Biosensing, Microfluidics, and Microsystems team, led by Wyss Senior Engineer Adama Sesay, Ph.D., together with the Female Reproductive Health team, has received the 2026 Lush Science Prize. The prize recognizes their work developing next-generation, sensor-integrated human Organ…

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Materializing safe, on-demand living therapeutics

Jessica Leff — Thu, 14 May 2026 17:55:55 +0000

By Benjamin Boettner (BOSTON) — Patient recovery from many debilitating conditions and diseases could be sped up significantly and be more effective if drugs and therapeutic molecules were delivered right to where they are needed in the body, over the entire regenerative process, and in doses finely tuned to therapeutic needs. An intriguing way to achieve this is the use of implantable…

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Growing liver tissue on demand directly in the body

Jessica Leff — Fri, 17 Apr 2026 17:55:10 +0000

By Benjamin Boettner (BOSTON) — In patients developing end-stage liver disease, the damage has become too severe for the liver’s normally extraordinary regenerative capacity to repair or compensate for it. Once this “point of no return” has been reached, the only option is an organ transplant. However, getting a liver transplant is extremely difficult due to high demand and limited supply…

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Toward autonomous self-organizing biological robots with a nervous system

Mariel Schoen — Mon, 16 Mar 2026 18:30:42 +0000

By Benjamin Boettner (BOSTON) — Biobots, whose growing line of variants started with Xenobots, are fascinating tiny self-powered living robots built exclusively using frog embryonic cells. Originally developed in the laboratories of Wyss Institute Associate Faculty member and Tufts University Professor Michael Levin, Ph.D. and his collaborators at University of Vermont…

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Nucleic Acid Delivery Consortium

Mariel Schoen — Fri, 13 Mar 2026 15:13:09 +0000

Nucleic acid therapies are emerging as a revolutionary class of medicines. Using engineered DNA or RNA molecules, they treat diseases at their genetic source, thus offering potential cures for a large variety of disorders, ranging from genetic disorders to cancers and infectious diseases. Different technologies, including mRNA, short interfering RNAs (siRNA), antisense oligonucleotides (ASOs)…

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Wyss Institute-led collaboration awarded by ARPA-H PRINT program to engineer off-the-shelf, universal, transplant-ready graft for liver failure

Jessica Leff — Fri, 16 Jan 2026 14:55:47 +0000

By Benjamin Boettner (BOSTON) — The majority of human illnesses are caused by damage to a single organ, like the liver, whose failure accounts for 2M deaths worldwide every year. Orthotopic transplants are the only curative therapy available, but the severe shortage of donor organs, which are reserved for the most severe cases, leaves millions of patients without an accessible solution.

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20-ish Questions with Michael Levin

Jessica Leff — Thu, 23 Oct 2025 15:05:20 +0000

20-ish Questions shows a different side of Wyss Institute faculty, touching on aspects of their personal life, hobbies, interests, as well as their research. This round follows Michael Levin, an Associate Faculty member of the Wyss Institute, as well as the Director of the Allen Discovery Center at Tufts and Tufts Center for Regenerative and Developmental Biology, and a Distinguished Professor…

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