Wyss InstituteBioinspired Therapeutics – Wyss Institute

Recapitulating intramuscular vaccination with mRNA vaccines in patient-specific Lymphoid Organ Chips

Mariel Schoen — Fri, 17 Jul 2026 13:55:40 +0000

By Benjamin Boettner (BOSTON) — The protective abilities of the Moderna and BioNTech mRNA vaccines developed against COVID-19 saved millions of lives during the pandemic and put this platform technology in the spotlight of vaccine research. By now, mRNA vaccines for other infectious diseases, such as influenza, RSV, and HIV are being tested in clinical trials and highly anticipated.

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The Wyss Institute’s 2026-2027 Validation Projects

Jessica Leff — Mon, 06 Jul 2026 14:00:41 +0000

Each year, the Wyss Institute’s Validation Project program identifies technologies that are ready to move beyond the discovery and into the validation phase. Through dedicated funding, technical resources, business development support, market research, and engagement with clinicians, investors, industry experts, and key opinion leaders, the program helps research teams de-risk high-impact…

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Machine-learning how to overcome antibiotic-resistant gonorrhea

Jessica Leff — Wed, 17 Jun 2026 17:55:26 +0000

By Benjamin Boettner (BOSTON) — With tens of millions of annual cases, gonorrhea is the second most frequently reported sexually transmitted infection (STI). In the U.S. alone, over 600,000 cases are reported each year. If left untreated, gonorrhea can result in severe reproductive health issues, including infertility in both women and men, and pelvic inflammatory disease.

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David Chou on keeping people safe from radiation on Earth and beyond

Jessica Leff — Thu, 28 May 2026 13:00:27 +0000

The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and beyond. David Chou’s work is literally out of this world! In addition to identifying radiation countermeasures for use on Earth, he is part of the AVATAR project, which aims to understand how humans…

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Decoding inflammatory bowel disease – on a chip

Jessica Leff — Thu, 21 May 2026 09:30:43 +0000

By Benjamin Boettner (BOSTON) — Inflammatory bowel disease (IBD), which comprises the inflammatory conditions Crohn’s disease and ulcerative colitis, affects about 1.6 million Americans, many of whom cannot be effectively treated. This is mostly due to a lack of understanding of what exactly causes the increased inflammation, fibrosis, and compromised intestinal barrier that underlie this…

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Multidisciplinary Wyss team receives 2026 Lush Prize Science Award

Jessica Leff — Mon, 18 May 2026 18:30:48 +0000

(BOSTON) — The Wyss Institute for Biologically Inspired Engineering at Harvard University is proud to announce that the Biosensing, Microfluidics, and Microsystems team, led by Wyss Senior Engineer Adama Sesay, Ph.D., together with the Female Reproductive Health team, has received the 2026 Lush Science Prize. The prize recognizes their work developing next-generation, sensor-integrated human Organ…

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Next-Gen Toxicology: Inside the Organ Chip Revolution with Donald Ingber

Jessica Leff — Wed, 06 May 2026 17:06:35 +0000

In this episode of ToxChats, hosts Lauren Walker and Sarah Benjamin sit down with the groundbreaking Donald Ingber—visionary scientist, engineer, and Founding Director of the Wyss Institute. Ingber shares how his unique path through medicine, biology, and design converged to spark breakthroughs such as human Organ Chips—systems that are redefining toxicology, drug development, and disease modeling.

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20-ish Questions with Donald E. Ingber

Jessica Leff — Fri, 01 May 2026 12:00:26 +0000

20-ish Questions shows a different side of Wyss Institute faculty, touching on aspects of their personal life, hobbies, interests, as well as their research. This round follows Donald E. Ingber, the Founding Director and a Core Faculty member at the Wyss Institute. He is also the Judah Folkman Professor of Vascular Biology at Harvard Medical School and Boston Children’s Hospital, as well as the…

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Alex Li on enabling technology translation

Jessica Leff — Thu, 30 Apr 2026 12:50:55 +0000

The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and beyond. Alex Li has always been fascinated by the idea of using living systems to make a positive impact. He initially pursued his interest in science, but after working at a venture capital firm…

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Wyss Institute technologies enable breakthrough in astronaut health research aboard NASA’s Artemis II mission

Jessica Leff — Thu, 09 Apr 2026 14:55:20 +0000

By Alexandra Jirstrand (BOSTON) – Launched on April 1, 2026, Artemis II is a historic, approximately 10-day lunar flyby mission that is sending four astronauts farther into space than any humans have traveled since the Apollo era, marking a critical step toward sustained lunar exploration and future missions to Mars. The Wyss Institute for Biologically Inspired Engineering at Harvard…

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