Wyss InstituteManufacturing – Wyss Institute

Dispersible Gas Carriers: Enhancing Efficiency in Biomanufacturing

Jessica Leff — Mon, 10 Aug 2026 15:12:47 +0000

The bioeconomy is being held back not by biology, but by the physics of getting gas into water at scale to support bioproduction by microbial and mammalian cells. Oxygen (O₂) and other gases are poorly soluble in water, and dissolving them at scale requires mechanical sparging and mixing systems that cause foaming, shear stress, contamination, and uneven gas distribution throughout the reactor.

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Wyss Institute receives Massachusetts Life Science Center award to advance metabolomics and lipidomics research across Massachusetts ecosystem

Jessica Leff — Wed, 22 Jul 2026 14:03:23 +0000

By Benjamin Boettner (BOSTON) — The Wyss Institute at Harvard University has received an award from the Massachusetts Life Science Center (MLSC), enabling it to host a next-generation metabolomics and lipidomics analytical platform. The platform will allow its researchers to creatively pursue new approaches to biomarker and drug discovery across multiple health challenges the Institute is…

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Reimagining a World Without Terminal Illness

Jessica Leff — Mon, 16 Jun 2025 15:00:52 +0000

As he battles metastatic skin cancer, Wyss Scientific Instrument maker John Caramanica is more motivated than ever to do his part in fabricating technologies to improve the health of others and our planet. Credit: Wyss Institute at Harvard University…

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Elizabeth Hann on Using Microbes to Save the Earth

Jessica Leff — Tue, 29 Apr 2025 13:15:49 +0000

The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and beyond. Imagine grabbing a power bar that contains proteins produced by cyanobacteria or a device that allows you to produce all of your own food with just electricity. This future…

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Newly discovered cyanobacteria could help sequester carbon from oceans and factories

Jessica Leff — Tue, 29 Oct 2024 12:58:56 +0000

By Lindsay Brownell (BOSTON) — An international coalition of researchers from the United States and Italy has discovered a novel strain of cyanobacteria, or algae, isolated from volcanic ocean vents that is especially adept at growing rapidly in the presence of CO2 and readily sinks in water, making it a prime candidate for biologically-based carbon sequestration projects and bioproduction of…

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3D-printed blood vessels bring artificial organs closer to reality

Jessica Leff — Wed, 07 Aug 2024 16:55:18 +0000

By Lindsay Brownell (BOSTON) — Growing functional human organs outside the body is a long-sought “holy grail” of organ transplantation medicine that remains elusive. New research from Harvard’s Wyss Institute for Biologically Inspired Engineering and John A. Paulson School of Engineering and Applied Science (SEAS) brings that quest one big step closer to completion. A team of scientists…

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The Wyss Institute’s 2024-2025 Validation Projects

Jessica Leff — Wed, 29 May 2024 14:55:23 +0000

Every year the Wyss Institute names a class of Validation Projects whose teams receive dedicated funding, business development support, and other resources to advance their promising technologies towards commercialization. They also collaborate with key opinion leaders, investors, and potential customers to de-risk their innovations and speed their progress to the market. This year…

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Circe Bioscience licenses technology to decarbonize industry with microbes developed at Wyss Institute at Harvard University

Jessica Leff — Wed, 15 May 2024 10:55:37 +0000

By Lindsay Brownell (BOSTON) — The Wyss Institute for Biologically Inspired Engineering at Harvard University announced today that Circe, a startup developed at the Institute and spun out of Harvard, has signed a worldwide, exclusive licensing agreement coordinated by Harvard’s Office of Technology Development (OTD) to commercialize a novel bioproduction technology that could significantly…

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Metabolically Labeled CAR-T Cells Against Cancer

Jessica Leff — Wed, 01 May 2024 17:03:45 +0000

In recent years, adoptive T cell therapies like CAR-T cell therapy – in which T cells are obtained from a patient, genetically enhanced ex vivo, and infused back into the same patient – have shown spectacular success in the treatment of blood cancers, including leukemias, lymphomas, and more lately multiple myelomas. However, not all patients with a given blood cancer benefit equally from this…

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Catalytic Materials: Cheaper, Better Air Purification for a Healthier World

Mariel Schoen — Tue, 30 Apr 2024 20:22:04 +0000

Catalytic converters are the most widely used kind of air pollution control device, and are installed in many smokestacks and car tailpipes. However, standard catalytic converters are very expensive because the catalysts used in them are precious metals like platinum, meaning they are not always replaced as often as they should be, and are the target of theft in lower-income areas.

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