Wyss InstituteTherapeutics – Wyss Institute

Building big with DNA gets a software upgrade

Jessica Leff — Wed, 16 Sep 2026 13:55:09 +0000

By Benjamin Boettner (BOSTON) — 44 years ago, Nadrian Seeman published his groundbreaking ideas on using DNA as a structural material, expanding DNA’s significance way beyond that as a carrier of genetic information. Since then, the steadily growing field of DNA nanotechnology has seen numerous innovations. One of them was the DNA origami technique, which enables researchers to fold a single…

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Jennifer (Jen) Bays on building a therapy to repair vascular barriers

Jessica Leff — Mon, 31 Aug 2026 12:30:01 +0000

The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and beyond. Jen Bays loves building things. At home, that might mean assembling LEGO bricks or IKEA furniture. At work, it means transforming an observation into a complete scientific story concluding…

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Researchers clear major obstacle in genetic engineering of proteins

Jessica Leff — Wed, 26 Aug 2026 15:13:59 +0000

By STEPHANIE DUTCHEN / Harvard Medical School Communications (BOSTON) — Scientists have been hard at work for more than 20 years to instruct biological systems, such as E. coli cells, to produce proteins they don’t naturally do. Success could mean faster, cheaper, innovative solutions for medicine, agriculture, materials science, environmental remediation, and other industries.

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Accelerating biomedical innovation with AI through collaborative iteration

Mariel Schoen — Thu, 06 Aug 2026 13:35:25 +0000

By Mariel Schoen Long before ChatGPT brought Artificial Intelligence (AI) into the public spotlight, scientists at the Wyss Institute were using AI-driven computational approaches, including machine learning and deep learning, to solve complex biomedical problems and develop new technology innovations. Today, while much of the field is racing to build larger models, the Institute is focused…

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Harkamal (Hark) Jhajj on rewiring immune cells to repair fractured bones

Jessica Leff — Wed, 29 Jul 2026 13:52:41 +0000

The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and beyond. Harkamal (Hark) Jhajj is always climbing physical and metaphorical mountains. In his spare time, he loves doing physical activities and exploring nature by hiking and visiting national parks.

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Wyss Institute receives Massachusetts Life Science Center award to advance metabolomics and lipidomics research across Massachusetts ecosystem

Jessica Leff — Wed, 22 Jul 2026 14:03:23 +0000

By Benjamin Boettner (BOSTON) — The Wyss Institute at Harvard University has received an award from the Massachusetts Life Science Center (MLSC), enabling it to host a next-generation metabolomics and lipidomics analytical platform. The platform will allow its researchers to creatively pursue new approaches to biomarker and drug discovery across multiple health challenges the Institute is…

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Tackling cancer through riding and research

Jessica Leff — Mon, 20 Jul 2026 13:41:21 +0000

By Jessica Leff Imagine it’s 5:50 AM on a Saturday morning in August. The sun’s only been out for 20 minutes, but that hasn’t stopped thousands of bicyclists and an equal number of volunteers from gathering in central Massachusetts. There’s a feeling of anticipation as the clock keeps ticking, getting closer to 6:00 AM. Everyone is there for the same reason: to raise money for cancer research…

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The Wyss Institute’s 2026-2027 Validation Projects

Jessica Leff — Mon, 06 Jul 2026 14:00:41 +0000

Each year, the Wyss Institute’s Validation Project program identifies technologies that are ready to move beyond discovery and into the validation phase. Through dedicated funding, technical resources, business development support, market research, and engagement with clinicians, investors, industry experts, and key opinion leaders, the program helps research teams de-risk high-impact innovations…

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Machine-learning how to overcome antibiotic-resistant gonorrhea

Jessica Leff — Wed, 17 Jun 2026 17:55:26 +0000

By Benjamin Boettner (BOSTON) — With tens of millions of annual cases, gonorrhea is the second most frequently reported sexually transmitted infection (STI). In the U.S. alone, over 600,000 cases are reported each year. If left untreated, gonorrhea can result in severe reproductive health issues, including infertility in both women and men, and pelvic inflammatory disease.

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David Chou on keeping people safe from radiation on Earth and beyond

Jessica Leff — Thu, 28 May 2026 13:00:27 +0000

The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and beyond. David Chou’s work is literally out of this world! In addition to identifying radiation countermeasures for use on Earth, he is part of the AVATAR project, which aims to understand how humans…

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