Discipline: Biotechnology
144 Results for 'Biotechnology'
- Technologies (17)
- Team (0)
- News (102)
- Events (0)
- Multimedia (25)
- Publications (0)
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Technologies 17
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Brain targeting of drugs and diagnostics
In its Brain Targeting Program, a Wyss team led by Founding Director Donald Ingber, M.D., Ph.D. and Staff Program Lead James Gorman, M.D., Ph.D. is developing improved approaches to target drugs and diagnostics to the brain. Leveraging the human blood-brain barrier (BBB) Chip technology developed by Ingber’s team, combined with advanced antibody R&D capabilities, the... -
Digital information storage in DNA
The genetic material DNA has garnered considerable interest as a medium for digital information storage because its density and durability are superior to those of existing silicon-based storage media. For example, DNA is at least 1000-fold more dense than the most compact solid-state hard drive and at least 300-fold more durable than the most stable... -
Synthetic AAV virus capsids for advanced gene therapy
The protein shell (capsid) of Adeno-associated viruses (AAV) are presently the most promising delivery vehicles for various in vivo gene therapies. AAVs are non-pathogenic and, through past engineering efforts, have become safe due to their inability to integrate into and damage the genome of target cells. Rather, the delivered DNA containing a therapeutic gene of... -
abbieSense Anaphylaxis Diagnostic
The molecule histamine plays a primary role in the anaphylaxis reaction, which is a major cause of illness and death in people with severe allergies. Histamine is a very small molecule composed of only seventeen atoms, making it a challenging target to detect. To date, no diagnostic test exists that can measure histamine levels accurately... -
Customizable scaffolds for faster, higher-quality T cell production
Immunotherapy, or tweaking the body’s own immune system to treat disease, is attracting significant attention in the medical field for its potential to offer long-lasting cures with fewer side effects than chemotherapy or other drugs. One type of immunotherapy involves isolating T cells (a type of white blood cell) from a patient’s body, sometimes modifying... -
RAPID testing for food contaminants
Contamination of food by microorganisms such as certain bacteria, viruses and fungi is a constant concern, with even miniscule amounts of certain species posing a risk for foods to become unsafe and spoiled during storage. Current safety and quality tests are often not sensitive enough to detect rare species, and because they first require the...
News 102
Multimedia 25
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Video/AnimationOrigami OrgansA multidisciplinary team of scientists, engineers, and architectural designers are developing Origami Organs that could function like artificial kidneys. Credit: Wyss Institute at Harvard University -
Video/AnimationLight-driven fine chemical production in yeast biohybridsWyss Institute Core Faculty member Neel Joshi explains the concept of yeast biohybrids and how they can be used to harvest energy from light to drive the production of fine chemicals. Credit: Wyss Institute at Harvard University -
Video/AnimationabbieSenseabbieSense is a Wyss technology that can detect histamine levels in human body fluids and determine the severity of an allergic reaction, which could help save the lives of patients with severe allergies. Credit: Wyss Institute at Harvard University -
Video/AnimationNew Wyss Institute Initiative – 3D Organ EngineeringWyss Institute Core Faculty members Christopher Chen and Jennifer Lewis describe the Wyss Institute’s new initiative focused on organ engineering, which leverages our expertise in biomaterials, tissue engineering, three dimensional biofabrication, and stem cell development. -
Audio/PodcastFormer DI Hoopster Searches For Athletic Boost In The MicrobiomeFormer DI Hoopster Searches For Athletic Boost In The Microbiome was originally broadcast on WBUR’s Only a Game on August 4, 2017. The story features Wyss Core Faculty member George Church and Postdoctoral Fellow Jonathan Scheiman. The original broadcast story can be found here. -
Video/AnimationCRISPR-Cas: Molecular RecordingIn this video, Wyss Institute and Harvard Medical School researchers George Church and Seth Shipman explain how they engineered a new CRISPR system-based technology that enables the chronological recording of digital information, like that representing still and moving images, in living bacteria. Credit: Wyss Institute at Harvard University