Publications

Publications from our faculty. In order to find a specific publication, use the search box below to search by author, title, journal or date.

January 14, 2022
Cell Reports Methods
Discovery and validation of human genomic safe harbor sites for gene and cell therapies

Erik Aznauryan, Alexander Yermanos, Elvira Kinzina, Anna Devaux, Edo Kapetanovic, Denitsa Milanova, George M. Church, Sai T. Reddy
March 18, 2021
Biotechnology and Bioengineering
Gene switch for l-glucose-induced biopharmaceutical production in mammalian cells

Tobias Strittmatter, Sabina Egli, Adrian Bertschi, Richard Plieninger, Daniel Bojar, Mingqi Xie, Martin Fussenegger
January 10, 2022
Journal of Clinical Oncology
Donor Clonal Hematopoiesis and Recipient Outcomes After Transplantation

Christopher J Gibson, Haesook T Kim, Lin Zhao, H Moses Murdock, Bryan Hambley, Alana Ogata, Rafael Madero-Marroquin, Shiyu Wang, Lisa Green, Mark Fleharty, Tyler Dougan, Chi-An Cheng, Brendan Blumenstiel, Carrie Cibulskis, Junko Tsuji, Madeleine Duran, Christopher D Gocke, Joseph H Antin, Sarah Nikiforow, Amy E DeZern, Yi-Bin Chen, Vincent T Ho, Richard J Jones, Niall J Lennon, David R Walt, Jerome Ritz, Robert J Soiffer, Lukasz P Gondek, R Coleman Lindsle
December 8, 2021
Cell Host & Microbe
Engineered bacteria recycle tumor metabolic waste to boost immunotherapy

Juan R. Cubillos-Ruiz, Andres Cubillos-Ruiz
January 14, 2022
ACS Nano
High-Throughput, High-Multiplex Digital Protein Detection with Attomolar Sensitivity

Connie Wu, Tyler J. Dougan, and David R. Walt
April 16, 2021
Circulation Research
Mechanisms of Congenital Heart Disease Caused by NAA15 Haploinsufficiency

Tarsha Ward, Warren Tai, Sarah Morton, Francis Impens, Petra Van Damme, Delphi Van Haver, Evy Timmerman, Gabriela Venturini, Kehan Zhang, Min Young Jang, Jon A L Willcox, Alireza Haghighi, Bruce D Gelb, Wendy K Chung, Elizabeth Goldmuntz, George A Porter Jr, Richard P Lifton, Martina Brueckner, H Joseph Yost, Benoit G Bruneau, Joshua Gorham, Yuri Kim, Alexandre Pereira, Jason Homsy, Craig C Benson, Steven R DePalma, Sylvia Varland, Christopher S Chen, Thomas Arnesen, Kris Gevaert, Christine Seidman, J G Seidman
December 21, 2021
Cell Chemical Biology
Increased energy demand from anabolic-catabolic processes drives β-lactam antibiotic lethality

Michael A Lobritz, Ian W Andrews, Dana Braff, Caroline B M Porter, Arnaud Gutierrez, Yoshikazu Furuta, Louis B G Cortes, Thomas Ferrante, Sarah C Bening, Felix Wong, Charley Gruber, Christopher W Bakerlee, Guillaume Lambert, Graham C Walker, Daniel J Dwyer, James J Collins
December 22, 2021
Biomaterials
Cryogel vaccines effectively induce immune responses independent of proximity to the draining lymph nodes

Alexander J Najibi, Ting-Yu Shih, David J Mooney
December 29, 2021
Advanced Healthcare Materials
Ultra-Rapid Method for Coating Electrochemical Sensors with Antifouling Conductive Nanomaterials Enables Highly Sensitive Multiplexed Detection in Whole Blood

Sanjay S. Timilsina, Nolan Durr, Mohamed Yafia, Hani Sallum, Pawan Jolly, Donald E. Ingber
January 3, 2022
Nature Biomedical Engineering
Enhanced tendon healing by a tough hydrogel with an adhesive side and high drug-loading capacity

Benjamin R. Freedman, Andreas Kuttler, Nicolau Beckmann, Sungmin Nam, Daniel Kent, Michael Schuleit, Farshad Ramazani, Nathalie Accart, Anna Rock, Jianyu Li, Markus Kurz, Andreas Fisch, Thomas Ullrich, Michael W. Hast, Yann Tinguely, Eckhard Weber & David J. Mooney
November 30, 2021
Biomaterials
Imiquimod-gemcitabine nanoparticles harness immune cells to suppress breast cancer

Bijay Singh, Sushila Maharjan, Daniel C Pan, Zongmin Zhao, Yongsheng Gao, Yu Shrike Zhang, Samir Mitragotri
December 8, 2021
American Journal of Physiology: Cell Physiology
Notch1 and Notch3 coordinate for pericyte-induced stabilization of vasculature

Juliann B. Tefft, Jennifer L. Bays, Alex Lammers, Sudong Kim, Jeroen Eyckmans, and Christopher S. Chen
November 18, 2021
Journal of Clinical Oncology
Donor Clonal Hematopoiesis and Recipient Outcomes After Transplantation

Christopher J Gibson, Haesook T Kim, Lin Zhao, H Moses Murdock, Bryan Hambley, Alana Ogata, Rafael Madero-Marroquin, Shiyu Wang, Lisa Green, Mark Fleharty, Tyler Dougan, Chi-An Cheng, Brendan Blumenstiel, Carrie Cibulskis, Junko Tsuji, Madeleine Duran, Christopher D Gocke, Joseph H Antin, Sarah Nikiforow, Amy E DeZern, Yi-Bin Chen, Vincent T Ho, Richard J Jones, Niall J Lennon, David R Walt, Jerome Ritz, Robert J Soiffer, Lukasz P Gondek, R Coleman Lindsley
November 18, 2021
Nature Nanotechnology
Supramolecular arrangement of protein in nanoparticle structures predicts nanoparticle tropism for neutrophils in acute lung inflammation

Jacob W. Myerson, Priyal N. Patel, Kathryn M. Rubey, Marco E. Zamora, Michael H. Zaleski, Nahal Habibi, Landis R. Walsh, Yi-Wei Lee, David C. Luther, Laura T. Ferguson, Oscar A. Marcos-Contreras, Patrick M. Glassman, Liudmila L. Mazaleuskaya, Ian Johnston, Elizabeth D. Hood, Tea Shuvaeva, Jichuan Wu, Hong-Ying Zhang, Jason V. Gregory, Raisa Y. Kiseleva, Jia Nong, Tilo Grosser, Colin F. Greineder, Samir Mitragotri, George S. Worthen, Vincent M. Rotello, Joerg Lahann, Vladimir R. Muzykantov & Jacob S. Brenner
November 23, 2021
Nature Communications
Programmable microbial ink for 3D printing of living materials produced from genetically engineered protein nanofibers

Anna M. Duraj-Thatte, Avinash Manjula-Basavanna, Jarod Rutledge, Jing Xia, Shabir Hassan, Arjirios Sourlis, Andrés G. Rubio, Ami Lesha, Michael Zenkl, Anton Kan, David A. Weitz, Yu Shrike Zhang & Neel S. Joshi
November 29, 2021
PNAS
Kinematic self-replication in reconfigurable organisms

Sam Kriegman, Douglas Blackiston, Michael Levin, and Josh Bongard
November 16, 2021
eLife
Framework for rapid comparison of extracellular vesicle isolation methods

Dmitry Ter-Ovanesyan, Maia Norman, Roey Lazarovits, Wendy Trieu, Ju-Hyun Lee, George Church, David R Walt
November 16, 2021
Advanced Science
Directing Cholangiocyte Morphogenesis in Natural Biomaterial Scaffolds

Quinton Smith,Jennifer Bays, Linqing Li, Haniyah Shareef, Christopher S. Chen, Sangeeta N. Bhatia
November 16, 2021
Journal of Cystic Fibrosis
Modeling pulmonary cystic fibrosis in a human lung airway-on-a-chip

Roberto Plebani, Ratnakar Potla, Mercy Soong, Haiqing Bai, Zohreh Izadifar, Amanda Jiang, Renee N. Travis, Chaitra Belgur, Alexandre Dinis, Mark J. Cartwright, Rachelle Prantil-Baun, Pawan Jolly, Sarah E. Gilpin ,Mario Romano Donald E. Ingber
October 22, 2021
STAR Protocols
MegaGate: A toxin-less gateway molecular cloning tool

Christian Kramme, Alexandru M Plesa, Helen H Wang, Bennett Wolf, Merrick Pierson Smela, Xiaoge Guo, Richie E Kohman, Pranam Chatterjee, George M Church