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Publications

Publications from our faculty. In order to find a specific publication, use the search box below to search by author, title, journal or date.

May 17, 2025
Cell Reports
Machine-guided cell-fate engineering

Evan Appleton, Jenhan Tao, Songlei Liu, Christopher Glass, Gregory Fonseca, George Church
February 4, 2025
Bioengineering & Translational Medicine
Stem cell therapies in the clinic

Shrinivas Acharya, Suyog Shaha, Michael Griffith Bibbey, Malini Mukherji, Zongmin Zhao, Samir Mitragotri
May 20, 2025
Journal of the American Chemical Society
Biocatalytic Regulation of Peptide Self-Assembly for Biomineralization

Zhaoqianqi Feng, David J Mooney
May 21, 2025
European Heart Journal
Empagliflozin enhances metabolic efficiency and improves left ventricular hypertrophy in a hypertrophic cardiomyopathy mouse model

Tomas Baka , Jarrod Moore , Fuzhong Qin , Salva R Yurista , Aifeng Zhang , Huamei He , Jordan M Chambers , Dominique Croteau , Raghuveera K Goel , Hunter Smith , Miranda C Wang , Christopher S Chen , Ion A Hobai , Martina Rombaldova , Ondrej Kuda , Jil C Tardiff , James A Balschi , David R Pimentel , Christine E Seidman , Jonathan G Seidman , Andrew Emili , Wilson S Colucci , Ivan Luptak
May 15, 2025
Nature Biotechnology
Self-assembling protein nanoparticles for cytosolic delivery of nucleic acids and proteins

Feyisayo Eweje, Vanessa Ibrahim, Aram Shajii, Michelle L. Walsh, Kiran Ahmad, Assma Alrefai, Dominie Miyasato, Jessie R. Davis, Hyunok Ham, Kaicheng Li, Michael Roehrl, Carolyn A. Haller, David R. Liu, Jiaxuan Chen & Elliot L. Chaikof
May 9, 2025
ACS Sensors
DNA-PAINT Imaging with Hydrogel Imprinting and Clearing

Johannes Stein, Lorenzo Magni, George M. Church
May 1, 2025
Review of Scientific Instruments
Fabrication and mounting of near-critical silicone gels for mechanical testing of colloidal solids

J Zsolt Terdik, David A Weitz, Frans Spaepen
April 21, 2025
PNAS
A diverse single-stranded DNA-annealing protein library enables efficient genome editing across bacterial phyla

Gabriel T Filsinger, Aaron Mychack, Evan Lyerly, Camilla Henriksen, Thomas M Bartlett, Helene Kuchwara, Simon Eitzinger, Thomas G Bernhardt, Suzanne Walker, George M Church, Timothy M Wannier
April 22, 2025
Communications Biology
Basal Xenobot transcriptomics reveals changes and novel control modality in cells freed from organismal influence

Vaibhav P. Pai, Léo Pio-Lopez, Megan M. Sperry, Patrick Erickson, Parande Tayyebi & Michael Levin
January 17, 2025
ALTEX
Biology-inspired dynamic microphysiological system approaches to revolutionize basic research, healthcare and animal welfare

Uwe Marx , Sonja Beken, Zaozao Chen, Eva-Maria Dehne, Ann Doherty, Lorna Ewart, Suzanne C. Fitzpatrick, Linda G. Griffith, Zhongze Gu, Thomas Hartung, James Hickman, Donald E. Ingber, Seiichi Ishida, Jayoung Jeong, Marcel Leist, Lisa Levin, Donna L. Mendrick, Giorgia Pallocca, Stefan Platz, Marian Raschke, Lena Smirnova, Danilo A. Tagle, Martin Trapecar, Bas W. M. van Balkom, Janny van den Eijnden-van Raaij, Andries van der Meer, Adrian Roth
April 11, 2025
Cancer Immunology Research
First-in-Human Clinical Trial of Vaccination with WDVAX, a Dendritic Cell Activating Scaffold Incorporating Autologous Tumor Cell Lysate, in Metastatic Melanoma Patients

F Stephen Hodi, Anita Giobbie-Hurder, Kwasi Adu-Berchie, Srin Ranasinghe, Ana Lako, Mariano Severgnini, Emily M Thrash, Jason L Weirather, Joanna Baginska, Michael P Manos, Edward J Doherty, Alexander Stafford, Heather Daley, Jerome Ritz, Patrick A Ott, Kathleen L Pfaff, Scott J Rodig, Charles H Yoon, Glenn Dranoff, David J Mooney
April 11, 2025
Nature Communications
Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensates

Nadia A. Erkamp, Mina Farag, Yuanxin Qiu, Daoyuan Qian, Tomas Sneideris, Tingting Wu, Timothy J. Welsh, Hannes Ausserwöger, Tommy J. Krug, Gaurav Chauhan, David A. Weitz, Matthew D. Lew, Tuomas P. J. Knowles & Rohit V. Pappu
April 5, 2025
Bio-Protocol Journal
A Human Cervix Chip for Preclinical Studies of Female Reproductive Biology

Zohreh Izadifar, Donald E Ingber
April 14, 2025
PLOS Computational Biology
Revealing non-trivial information structures in aneural biological tissues via functional connectivity

Douglas Blackiston, Hannah Dromiack, Caitlin Grasso, Thomas F Varley, Douglas G Moore, Krishna Kannan Srinivasan, Olaf Sporns, Joshua Bongard, Michael Levin, Sara I Walker
April 16, 2025
Nature Communications
Dysregulation of N-terminal acetylation causes cardiac arrhythmia and cardiomyopathy

Daisuke Yoshinaga, Isabel Craven, Rui Feng, Maksymilian Prondzynski, Kevin Shani, Yashasvi Tharani, Joshua Mayourian, Milosh Joseph, David Walker, Raul H. Bortolin, Chrystalle Katte Carreon, Bridget Boss, Sheila Upton, Kevin Kit Parker, William T. Pu & Vassilios J. Bezzerides
April 8, 2025
Journal of the American Chemical Society
High-Throughput Extracellular Vesicle Isolation Using Plate-Based Size Exclusion Chromatography and Automation

Tal Gilboa, Dmitry Ter-Ovanesyan, Clarissa May Babila, Sara Whiteman, Shad Morton, David Kalish, Jamie Johnston, David Tesin, Matthew Davies, Jenny M. Tam, George M. Church, David R. Walt
April 9, 2025
Science Advances
Preference-based assistance optimization for lifting and lowering with a soft back exosuit

Philipp Arens, D Adam Quirk, Weiwei Pan, Yaniv Yacoby, Finale Doshi-Velez, Conor J Walsh
March 12, 2025
International Journal of Molecular Sciences
Host Serine Proteases and Antiviral Innate Immunity as Potential Therapeutic Targets in Influenza A Virus Infection-Induced COPD Exacerbations

Haiqing Bai, Melissa Rodas, Longlong Si, Yuncheng Man, Jie Ji, Roberto Plebani, Johnathan D Mercer, Rani K Powers, Chaitra Belgur, Amanda Jiang, Sean R R Hall, Rachelle Prantil-Baun, Donald E Ingber
March 26, 2025
ACS Applied Materials & Interfaces
Electrical Impedance Correlated to Flow Rate in Elastomeric Valves: An Analog Material Memory

Joel Dungan, Juanita Mathews, Jeffrey T. Borenstein, Michael Levin, Valencia Koomson
March 13, 2025
ACS Synthetic Biology
XanthoMoClo─A Robust Modular Cloning Genetic Toolkit for the Genera Xanthobacter and Roseixanthobacter

Maximillian P. M. Soltysiak, Audrey L. H. Ory, Andrew D. Lee, Caroline E. Christophersen, Amogh P. Jalihal, Michael Springer