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Publications

Publications from our faculty. In order to find a specific publication, use the search box below to search by author, title, journal or date.

July 1, 2025
American Journal of Respiratory Cell and Molecular Biology
Novel Immune Response Evasion Strategy to Redose Adeno-associated Viral Vectors and Prolong Survival in Surfactant Protein-B-Deficient Mice

Martin H Kang, Sylvia P Thomas, Caralyn Westley, Thomas Blouin, Liqun Xu, Ying Kai Chan, Erin Lisk, Sarah E Allen, Arul Vadivel, Kennedy Nangle, Janani Ramamurthy, Yanlong Pei, Lunndon A Lewis, Jessica J Chiang, Martin J Romeo, Silvia Vaena, Elizabeth C O'Quinn, Henry D Schrecker, Casey G Langdon, Paul J Nietert, George M Church, Jeffrey A Whitsett, Sarah K Wootton, Bernard Thébaud
July 2, 2025
Cancer Immunology Research
First-in-Human Clinical Trial of Vaccination with WDVAX, a Dendritic Cell-Activating Scaffold Incorporating Autologous Tumor Cell Lysate, in Patients with Metastatic Melanoma

F Stephen Hodi, Anita Giobbie-Hurder, Kwasi Adu-Berchie, Srin Ranasinghe, Ana Lako, Mariano Severgnini, Emily M Thrash, Jason L Weirather, Joanna Baginska, Michael P Manos, Edward J Doherty, Alexander Stafford, Heather Daley, Jerome Ritz, Patrick A Ott, Kathleen L Pfaff, Scott J Rodig, Charles H Yoon, Glenn Dranoff, David J Mooney
July 1, 2025
Communications Medicine
AI-enabled drug prediction and gene network analysis reveal therapeutic use of vorinostat for Rett Syndrome in preclinical models

Richard Novak, Tiffany Lin, Shruti Kaushal, Megan Sperry, Frederic Vigneault, Erica Gardner, Sahil Loomba, Kostyantyn Shcherbina, Vishal Keshari, Alexandre Dinis, Anish Vasan, Vasanth Chandrasekhar, Takako Takeda, Rahul Nihalani, Sevgi Umur, Jerrold R. Turner, Michael Levin & Donald E. Ingber
June 25, 2025
PNAS
Fluid dynamics model of the cerebral ventricular system

Haritosh Patel, Yu Xuan Huang, Duygu Dengiz, Mariya Pravdivtseva, Olav Jansen, Eckhard Quandt, and Joanna Aizenberg
June 12, 2025
Advanced Healthcare Materials
Aging on Chip: Harnessing the Potential of Microfluidic Technologies in Aging and Rejuvenation Research

Limor Zwi-Dantsis, Vignesh Jayarajan, George M. Church, Roger D. Kamm, João Pedro de Magalhães, Emad Moeendarbary
June 17, 2025
Advanced Healthcare Materials
In Vivo Accumulation of Regulatory T Cells Using Eliglustat-Loaded Cryogels

Einat. B. Vitner, Giovanni Bovone, Wei-Hung Jung, Junzhe Lou, Hugh Hankenson, Mason T. Dacus, Yoav Binenbaum, Kwasi Adu-Berchie, Alexander G. Stafford, Miguel C. Sobral, David J. Mooney
June 17, 2025
Nature Aging
Skin health and biological aging

David Furman, Johan Auwerx, Anne-Laure Bulteau, George Church, Virginie Couturaud, Laure Crabbe, Kelvin J. A. Davies, Anabelle Decottignies, Vadim N. Gladyshev, Brian K. Kennedy, Nicola Neretti, Carine Nizard, Karl Pays, Daisy Robinton, Vittorio Sebastiano, Rachel E. B. Watson, Meng C. Wang & Knut Woltjen
June 24, 2025
Nucleic Acids Research
Reusing excess staple oligonucleotides for economical production of DNA origami

Giorgia Isinelli , Christopher M Wintersinger , Matthew Aquilina , Pascal Lill , Olivia J Young , Jie Deng , William M Shih , Yang C Zeng
June 6, 2025
Advanced Science
The Morphological, Behavioral, and Transcriptomic Life Cycle of Anthrobots

Gizem Gumuskaya, Nikolai Davey, Pranjal Srivastava, Andrew Bender, Léo Pio-Lopez, Douglas Hazel, Michael Levin
June 10, 2025
Trends in Genetics
What does evolution make? Learning in living lineages and machines

Benedikt Hartl, Michael Levin
June 10, 2025
Nature Communications
Iterative transcription factor screening enables rapid generation of microglia-like cells from human iPSC

Songlei Liu, Li Li, Fan Zhang, Mariana Garcia-Corral, Katharina Meyer, Patrick R. J. Fortuna, Björn van Sambeek, Evan Appleton, Alex H. M. Ng, Parastoo Khoshakhlagh, Yuancheng Ryan Lu, James Cameron, Ricardo N. Ramirez, Yuting Chen, Chun-Ting Wu, Jeremy Y. Huang, Yuqi Tan, George Chao, John Aach, Elaine T. Lim, Jenny M. Tam, Soumya Raychaudhuri & George M. Church
May 29, 2025
Science
Expansion in situ genome sequencing links nuclear abnormalities to aberrant chromatin regulation

Ajay S Labade, Zachary D Chiang, Caroline Comenho, Paul L Reginato, Andrew C Payne, Andrew S Earl, Rojesh Shrestha, Fabiana M Duarte, Ehsan Habibi, Ruochi Zhang, George M Church, Edward S Boyden, Fei Chen, Jason D Buenrostro
May 15, 2025
Frontiers in Molecular Biosciences
Broad-spectrum coronavirus inhibitors discovered by modeling viral fusion dynamics

Charles B Reilly, Joel Moore, Shanda Lightbown, Austin Paul, Sylvie G Bernier, Kenneth E Carlson, Donald E Ingber
June 2, 2025
BMC Bioinformatics
Universal multilayer network embedding reveals a causal link between GABA neurotransmitter and cancer

Léo Pio-Lopez & Michael Levin
May 13, 2025
ACS Nano
Blueprints for Better Drugs: The Structural Revolution in Nanomedicine

Chad A. Mirkin, Robert Langer, Milan Mrksich, Adam A. Margolin, Sarah Hurst Petrosko, Natalie Artzi
May 22, 2025
Bioessays
Human Cervix Chip: A Preclinical Model for Studying the Role of the Cervical Mucosa and Microbiome in Female Reproductive Health

Zohreh Izadifar, Anna Stejskalova, Aakanksha Gulati, Ola Gutzeit, Donald E. Ingber
May 25, 2025
Journal of Translational Medicine
Patient-derived esophageal adenocarcinoma organ chip: a physiologically relevant platform for functional precision oncology

Sanjima Pal, Elee Shimshoni, Salvador Flores Torres, Mingyang Kong, Kulsum Tai, Veena Sangwan, Nicholas Bertos, Swneke Donovan Bailey, Julie Bérubé, Donald E. Ingber & Lorenzo Ferri
May 24, 2025
Journal for ImmunoTherapy of Cancer
Adoptively transferred macrophages for cancer immunotherapy

Kyung Soo Park, Alexander P Gottlieb, Morgan E Janes, Supriya Prakash, Neha Kapate, Vineeth Chandran Suja, Lily Li-Wen Wang, Jennifer L Guerriero, Samir Mitragotri
May 17, 2025
Cell Reports
Machine-guided cell-fate engineering

Evan Appleton, Jenhan Tao, Songlei Liu, Christopher Glass, Gregory Fonseca, George Church
February 4, 2025
Bioengineering & Translational Medicine
Stem cell therapies in the clinic

Shrinivas Acharya, Suyog Shaha, Michael Griffith Bibbey, Malini Mukherji, Zongmin Zhao, Samir Mitragotri