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Come join our Wyss community! We are bringing together world-class talent from different backgrounds, disciplines, industries and institutions in an open collaborative culture that empowers people to share their viewpoints and challenge their thinking to create novel solutions that change the world.

  • Our Work

    At the Wyss Institute, we leverage recent insights into how Nature builds, controls and manufactures to develop new engineering innovations. By emulating biological principles, we are developing disruptive technology solutions for healthcare, energy, architecture, robotics, and manufacturing, which are translated into commercial products and therapies through formation of new startups and corporate alliances.

    Our work revolves around eight core Focus Areas rooted in diverse fields. Learn more about our work and our model of technology translation.

    Credit: Wyss Institute at Harvard University
  • Our Benefits

    • Medical/Dental/Vision: We offer a variety of excellent medical, dental & vision plans. All coverage begins as of your start date.
    • Time Off: 3-4 weeks vacation, 12 sick days, 11.5 holidays, winter recess, and 3 paid personal days per year.
    • Retirement: University-funded retirement plan with full vesting after 3 years of service.
    • Tuition Assistance Program: Competitive tuition assistance program, $40 per class at the Harvard Extension School and discounted options through participating Harvard grad schools.
    • Transportation: Harvard offers a 50% discounted MBTA pass as well as additional options to assist employees in their daily commute.
    • Wellness Options: Harvard offers programs and classes at little or no cost, including stress management, nutrition, meditation and complimentary health services.

    Learn more about Harvard University benefits.

    We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions or any other characteristic protected by law.

Staff Positions

  • Director of Technology Commercialization
    Business Development and Technology Translation

    Reporting to the Senior Associate Provost and Chief Technology Development Officer, this position will be a key senior member of the OTD team supporting the Wyss Institute for Biologically Inspired Engineering at Harvard University (Wyss) in its efforts to translate cutting edge bio-inspired engineering innovations into commercial outcomes. This position will drive a cross-functional team approach to transforming business development opportunities into licensing and industry collaboration deals (with startups and larger companies) for technology developed at the Wyss, a dynamic, complex, mission-driven, multi-stakeholder organization. This position will work closely with the Wyss Technology Translation Director and the Wyss internal business development team members, as well as senior associate directors of OTD’s Wyss-focused intellectual property and transactions teams. Responsibilities will include: structuring licensing (including startup) and industrial partnerships to maximize strategic and scientific value; developing, negotiating, and finalizing all terms (including financial terms); obtaining input from and communicating status of negotiations with key stakeholders in a timely manner; ensuring compliance with Harvard policy and public mission; and overseeing due diligence. [45839BR]

    Harvard University is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law.

    Learn more

  • Research Associate III – Analytical-Immunology
    Research and Technology Development

    [45208BR] The Wyss Institute is seeking a highly motivated and innovative Research Associate III with experience developing and running immune assays and other analytical methods and techniques. The candidate must have a comprehensive understanding of the process to develop and run immunoassays. The specific testing would include characterizing biomaterials as well as how they modulate the immune system to support our platform technologies. The candidate must have experience with the following ELISAs, FlowCytometry, Cell Based Assays, and Cell Culture.

    Harvard University is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law.

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  • Functional Apparel Designer
    Research and Technology Development

    Reporting to the Director of Operations and working closely with the Platform Faculty, Staff, and Researchers, the Apparel Designer will take functional and technical requirements from an engineering and biomechanics team and interpret these into a broad range of prototyped garments; develops an understanding of the functional requirements of various wearable robot embodiments through discussions with engineers, scientists, biomechanists, and clinicians; provides design input, textile selection, pattern making, and iterative soft goods fabrication for wearable technical garments including components such as performance textiles, embedded sensors, actuators, batteries, and integrated wiring. [45745BR]

    Harvard University is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law.

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Academic Positions

  • Tissue and Organ Regeneration
    Postdoctoral Fellow Research

    We are building an interdisciplinary team to solve tissue and organ regeneration challenges – specifically in the liver, kidney, and vascular lineages. In addition to hiring an intellectual ‘bridge’ senior Staff Scientist who will bring both bench expertise and industry / startup experience to the table, we seek tissue engineering-focused Postdoctoral Fellow to the team, to help drive basic science findings from your future colleagues at Harvard, MIT, and Boston University into pre-clinical animal models, and eventually to patients. The successful applicants will join an internationally-renowned, multi-disciplinary team of experts in a recently established 3D Organ Engineering Focus Area at the Wyss Institute, located at the Longwood Medical Area in Boston. The Wyss Institute-based team members will serve as a physical hub focused on the translation of groundbreaking work developed by the labs of Prof. Jennifer Lewis (Initiative Co-Lead), Prof. Christopher Chen (Initiative Co-Lead), Prof. Sangeeta Bhatia, Prof. Don Ingber, and Prof. David Mooney. The Postdoctoral Fellow will work with the Staff Scientist to evaluate early-stage technologies for their potential therapeutic applications, and to implement relevant de-risking strategies needed to move the technology towards clinical applications within tissue fabrication, and organ regeneration.

    This postdoctoral trainee will participate in ongoing whole organ bioengineering initiatives at the Wyss Institute. Technically, these studies entail primary and stem cell culture, tissue and organ manufacturing, maintenance, and characterization of tissues during maturation, and, ultimately, in vivo implantation. This position will require a relatively independent researcher, as the direct faculty co-supervisors (Drs. Bhatia and Chen) are based off-site. Day-to-day supervision will be provided by the Staff Scientist, and regular meetings with both the PIs and other MIT- and BU-based postdoctoral and graduate trainee colleagues will be provided to ensure opportunities for formal and informal mentorship throughout the postdoctoral training period. This arrangement will yield a unique, multi-armed training environment, but also one that will select for independently-driven trainees. Finally, while candidates on an academic career track are encouraged to apply, the translational focus of this position might be better suited to trainees pursuing commercial- or application-centric professional paths.

    In the short-term, we aim to integrate several recently developed technologies to address clinical applications in tissue engineering and regenerative medicine. Specifically, 3D bioprinting and microfabrication will be used to create organ-specific tissues, including the kidney, liver, and heart. Several examples of foundational work on which this effort builds can be found at the following links:

    Miller et al Nat. Mat. (2012)
    Baranski et al PNAS (2013)
    Stevens et al Nat. Comm. (2013)
    Kolesky et al Adv. Mat. (2014)
    Kolesky et al PNAS (2016)
    Homan et al Sci. Rep. (2016)
    Stevens et al Sci.Trans. Med. (2017)

    PRINCIPAL ACTIVITIES: 

    • Participate in the development of large-scale organ-specific tissues, while working with a multi-disciplinary team that includes technical, clinical, and development collaborators.
    • Design, engineer, and iterate organ-specific constructs based on insights gleaned from collaborating team members who are focused on identifying cell-cell, cell-matrix, and soluble/circulating factors that influence tissue growth and function, with the aim of producing translationally-relevant model systems that enable pre-clinical testing.
    • Contribute to the isolation and/or maintenance of primary and/or stem cell-derived cell populations. Candidate must have experience with mammalian cell culture and aseptic technique.
    • Design and conduct implantation experiments in appropriate animal models.
    • Monitor and analyze organ-specific tissues during in vitro and in vivo expansion, including preparation and handling, collection and analysis of pre- and post-expanded cell populations/tissues, and functional assessment of tissue output.

    Responsibilities

    • Implement ‪quantitative in vitro assays for evaluating tissue functionality, stability, and safety.
    • Develop and standardize organ-specific tissue manufacturing and surgical protocols for in vivo studies in small and large animals.
    • Participate in writing research proposals, reports, patent applications, presentations, and publications, providing critical data, figures or information for grant and patent submissions.

    Qualifications

    • D. degree in a biological science, bioengineering, or related discipline, with a strong understanding of cell biology, physiology, and/or tissue engineering. Experience in an industrial / translational setting preferred but not required. Relevant post-doctoral training can be counted towards industrial experience.
      • Must demonstrate broad theoretical and practical knowledge within the fields of biofabrication, tissue engineering, and cell biology.
      • Strong scientific track record demonstrating well-organized design and execution of studies.
      • Extensive experience with in vivo and in vitro tissue engineering, characterization, and implantation.
      • Demonstrated success in leading and working in cross-functional teams.
      • Comfortable in a fast-paced translational environment and able to adjust workload based upon changing priorities.
      • Flexible and cooperative spirit with strong commitment to team efforts.
      • Strong oral and written communication skills, with a habit of paying significant attention to detail.

    Applications, assembled as single PDF files, should contain a complete resume, cover letter describing research interests and goals, full list of publications, copies of up to three relevant scientific papers, as well as the names and contact information of three references (expected to provide letters of recommendation). Applications should be sent to faculty_postdocs@wyss.harvard.edu using the subject line “TISSUE AND ORGAN REGENERATION.”

    Harvard University is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law.

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  • Rapid manufacturing of regenerative heart valves
    Postdoctoral Fellow Research

    Background: Prof. Kevin Kit Parker’s Disease Biophysics Group at the Harvard University Wyss Institute for Biologically Inspired Engineering seeks a talented post-doctoral fellow to work on the rapid manufacturing of regenerative heart valves, or JetValves. The candidate will use the proprietary rotary jet spinning technologies developed in the Parker lab to design, build, and test heart valve replacements using natural and synthetic polymeric nanofibers. The goal of this translational project – which is part of an international collaboration with the University of Zurich in Switzerland – is to complete the preclinical characterization of JetValves in preparation for a first-in-man clinical trial.

    Duties and Responsibilities: Working together with a team of engineers, chemists, and applied mechanicians, the candidate will be responsible for nanofiber production and valve manufacturing, quality assessment, and structural and functional validation in-vitro. This includes performing standards tests using methodologies such as Instron®, FTIR, SEM, microCT, pulse duplicator testing, and cell infiltration. The candidate is also expected to participate in the in-vivo and post-mortem validation of JetValves implanted in sheep, including analysis of explanted samples via SEM and immunohistochemistry.

    Qualifications: A Ph.D. in cardiovascular tissue engineering or related fields and expertise with in-vitro and/or in-vivo characterization of heart valves or heart valve replacements. A background in Materials Science and proven experience with nanofiber fabrication (e.g., electrospinning) or additive manufacturing methodologies (e.g., 3D printing) will be positively evaluated.

    Application procedure: Interested candidates should submit their application packet to Prof. Kevin Kit Parker (kkparker@g.harvard.edu) and his admin assistant Dr. Ben Smith (bdsmith@g.harvard.edu) as a single pdf file with the following documents: cover letter, CV, 3 relevant first author paper(s), and the names of three referees.

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  • In Vitro Modeling of the Cervico-Vaginal Epithelium for Understanding the Role of Microbiome in Vaginal Health
    Postdoctoral Fellow Research

    The Wyss Institute for Biologically Inspired Engineering at Harvard University invites applications for a postdoctoral fellow position in the Bioinspired Therapeutics & Discovery platform. The mission of the Wyss Institute is to discover the engineering principles that Nature uses to build living things; to pursue the high-risk research that is fundamental to advance this effort; and to harness these insights to create biologically-inspired materials and devices to advance human health and improve the environment – thereby revolutionizing clinical medicine and creating a more sustainable world.

    We seek outstanding postdoctoral applicants with expertise in female reproductive biology and physiology to join an interdisciplinary team of biologists and engineers for the development of novel in vitro “organ-on-chip” microsystems technologies to study and model vaginal and cervical epithelium in vitro and explore the role of the microbiome in maintaining vaginal health. Applicants are expected to hold a Ph.D. or M.D. and have a proven record of high quality publications in female reproductive biology, inflammation, and/or ecosystems. Strong interest in contributing to multidisciplinary teams (engineers, biologists/physiologists, clinicians) is critical for this position. Expertise in in vitro culture of primary epithelial cells, as well as knowledge of basic molecular and cell biology concepts and techniques is a must. Experience with stem cell culture/differentiation and microbiology would be beneficial but not necessary.

    The ideal candidate would bring expertise in female reproductive cell biology, physiology, and pathophysiology, with an interest in applying this expertise in combination with modern bioengineering practices towards the development of novel therapeutics to promote vaginal homeostasis. This postdoctoral fellow is expected to develop and lead an interdisciplinary research project aimed at creating microengineered “organ-on-chip” models, simulating human diseases and exploring their use in vaginal health.

    Applications, assembled as single PDF files, should contain a complete resume, cover letter describing research interests and goals, full list of publications, copies of up to three relevant scientific papers, as well as the names and contact information of three references (expected to provide letters of recommendation). Applications should be sent to faculty_postdocs@wyss.harvard.edu using the subject line “VAGINAL HEALTH APPLICATION.”

    Harvard University is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law.

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