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Careers

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Come join our Wyss community! We are bringing together world-class talent from different backgrounds, disciplines, industries and institutions in an open collaborative culture that empowers people to share their viewpoints and challenge their thinking to create novel solutions that change the world.

  • Our Work

    At the Wyss Institute, we leverage recent insights into how Nature builds, controls and manufactures to develop new engineering innovations. By emulating biological principles, we are developing disruptive technology solutions for healthcare, energy, architecture, robotics, and manufacturing, which are translated into commercial products and therapies through formation of new startups and corporate alliances.

    Our work revolves around seven core Focus Areas rooted in diverse fields. Learn more about our work and our model of technology translation.

    Credit: Wyss Institute at Harvard University
  • Our Benefits

    • Medical/Dental/Vision: We offer a variety of excellent medical, dental & vision plans. All coverage begins as of your start date.
    • Time Off: 3-4 weeks vacation, 12 sick days, 11.5 holidays, winter recess, and 3 paid personal days per year.
    • Retirement: University-funded retirement plan with full vesting after 3 years of service.
    • Tuition Assistance Program: Competitive tuition assistance program, $40 per class at the Harvard Extension School and discounted options through participating Harvard grad schools.
    • Transportation: Harvard offers a 50% discounted MBTA pass as well as additional options to assist employees in their daily commute.
    • Wellness Options: Harvard offers programs and classes at little or no cost, including stress management, nutrition, meditation and complimentary health services.

    Learn more about Harvard University benefits.

    We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions or any other characteristic protected by law.

Staff Positions

  • Research Assistant III – Human Bone Marrow
    Research and Technology Development

    We are seeking an enthusiastic and full time Research Assistant III who will use primary human hematopoietic cell cultures in microfluidic devices to study bone marrow dysfunction. [52155BR]

     

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  • Staff Scientist II – Viral Vector Development
    Research and Technology Development

    We are seeking a talented, energetic professional to join our community as a Staff Scientist in the Synthetic Biology Platform. This position provides a unique opportunity to perform cutting edge, hands-on research relating to the design, creation, and testing of new gene delivery vehicles. With an emphasis on viral vectors and viral-like particles, the candidate will focus on a variety of interdisciplinary research directions including: engineering new viral vectors; creating strategies to target specific organs of cell types; Increasing the safety profile and enabling re-dosing strategies; developing new scientific tools such as next generation viral tracers; tailoring delivery for specific diseases or conditions, such as neurological diseases or brain injury [52447BR]

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  • Research Assistant II – Biological Applications of DNA Nanotechnology
    Research and Technology Development

    We are seeking a talented individual to work as a Research Assistant II in Peng Yin’s lab. The lab specializes in developing and applying DNA-based technology, including the application of DNA probes to transform biomolecular imaging and understand cell and tissue organization. The successful candidate may work on a variety of these imaging projects, applying molecular biology and biochemistry protocols to construct, amplify, conjugate, or assemble components and probe sets (such as fluorescence in situ hybridization oligos or antibodies) and in turn apply them to recording or fluorescence imaging applications in vitro (e.g., proteins in solution) or on biological materials (e.g., live or fixed cells and tissues for IF, IHC, FISH protocols). [52170BR]

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Academic Positions

  • Development of Biomimetic Microsystems Aimed at Modeling Gastrointestinal Disorders
    Postdoctoral Fellows and Associates

    The Wyss Institute for Biologically Inspired Engineering at Harvard University invites applications for a postdoctoral fellow position in the Biomimetic Microsystems platform. The mission of the Wyss Institute is to discover the engineering principles that Nature uses to build living things; to pursue the high-risk research that is fundamental to advance this effort; and to harness these insights to create biologically-inspired materials and devices to advance human health and improve the environment – thereby revolutionizing clinical medicine and creating a more sustainable world.

    We seek outstanding postdoctoral applicants with expertise in intestinal cell biology and physiology and/or surface barrier (mucosal) inflammation to join an interdisciplinary team of biologists and engineers for the development of novel in vitro “organ-on-chip” microsystems technologies to study and model gastrointestinal disorders. Applicants are expected to hold a Ph.D. or M.D. and have a proven record of high quality publications in intestinal cell biology and/or inflammation. Strong interest in contributing to multidisciplinary teams (engineers, biologists/physiologists, clinicians) is critical for this position. Expertise in in vitro culture of intestinal cells, as well as knowledge of basic molecular and cell biology concepts and techniques is a must. Experience with stem cell culture/differentiation would be beneficial but not necessary.

    The ideal candidate would bring expertise in gastrointestinal cell biology, physiology, and pathophysiology, with an interest in applying this expertise in combination with modern bioengineering practices. This postdoctoral fellow is expected to develop and lead an interdisciplinary research project aimed at creating microengineered “organ-on-chip” models, simulating human diseases and exploring their use in drug discovery applications.

    Applications, assembled as single PDF files, should contain a complete resume, cover letter describing research interests and goals, full list of publications, copies of up to three relevant scientific papers, as well as the names and contact information of three references (expected to provide letters of recommendation). Applications should be sent to faculty_postdocs@wyss.harvard.edu using the subject line “GASTROINTESTINAL APPLICATION.”

    Harvard University is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law.

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  • In Vitro Modeling of the Cervico-Vaginal Epithelium for Understanding the Role of Microbiome in Vaginal Health
    Postdoctoral Fellows and Associates

    The Wyss Institute for Biologically Inspired Engineering at Harvard University invites applications for a postdoctoral fellow position in the Bioinspired Therapeutics & Discovery platform. The mission of the Wyss Institute is to discover the engineering principles that Nature uses to build living things; to pursue the high-risk research that is fundamental to advance this effort; and to harness these insights to create biologically-inspired materials and devices to advance human health and improve the environment – thereby revolutionizing clinical medicine and creating a more sustainable world.

    We seek outstanding postdoctoral applicants with expertise in female reproductive biology and physiology to join an interdisciplinary team of biologists and engineers for the development of novel in vitro “organ-on-chip” microsystems technologies to study and model vaginal and cervical epithelium in vitro and explore the role of the microbiome in maintaining vaginal health. Applicants are expected to hold a Ph.D. or M.D. and have a proven record of high quality publications in female reproductive biology, inflammation, and/or ecosystems. Strong interest in contributing to multidisciplinary teams (engineers, biologists/physiologists, clinicians) is critical for this position. Expertise in in vitro culture of primary epithelial cells, as well as knowledge of basic molecular and cell biology concepts and techniques is a must. Experience with stem cell culture/differentiation and microbiology would be beneficial but not necessary.

    The ideal candidate would bring expertise in female reproductive cell biology, physiology, and pathophysiology, with an interest in applying this expertise in combination with modern bioengineering practices towards the development of novel therapeutics to promote vaginal homeostasis. This postdoctoral fellow is expected to develop and lead an interdisciplinary research project aimed at creating microengineered “organ-on-chip” models, simulating human diseases and exploring their use in vaginal health.

    Applications, assembled as single PDF files, should contain a complete resume, cover letter describing research interests and goals, full list of publications, copies of up to three relevant scientific papers, as well as the names and contact information of three references (expected to provide letters of recommendation). Applications should be sent to faculty_postdocs@wyss.harvard.edu using the subject line “VAGINAL HEALTH APPLICATION.”

    Harvard University is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law.

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  • Brain Targeting Program Postdoctoral Fellow Position
    Postdoctoral Fellows and Associates

    The Wyss Institute for Biologically Inspired Engineering at Harvard University invites applications for a postdoctoral fellow position in the Brain Targeting Program (BTP). The position will focus on the discovery of new targets and engineered transport vehicles to carry therapeutic and diagnostic payloads into the brain. This position is an exciting opportunity to combine cutting edge, hands-on academic research with the strategic considerations of technology translation and product development.

    The Wyss Institute’s BTP, co-led by Donald Ingber, M.D., Ph.D., and James Gorman, M.D., Ph.D., is using novel proteomics and transcriptomic studies, coupled with a discovery platform that leverages novel human Organ Chips and other in vitro models of the blood-brain barrier (BBB) to develop improved methods of transport across the human BBB into the central nervous system (CNS). One of its core projects is a target discovery effort directed to identifying proteins on the BBB endothelial cell surface that are highly expressed and are enriched compared to the same protein on endothelial cells from other organs. These proteins will be evaluated for their potential to transport cargoes across the BBB by one of several mechanisms. They will then be tested to validate and prioritize them for the generation of antibody shuttles that bind to them. We are currently developing novel antibody shuttles directed against several known Ab shuttle targets. These will be tested in the human-cell based assays, in the state-of-the-art human in vitro BBB-Chip model, and eventually in humanized mouse models. The Wyss team is collaborating with several biopharmaceutical companies and other academic institutions to advance the Brain Transport Program. As part of this effort, we are exploring engineered transport vehicles to transport payloads such as anti-sense oligonucleotides into the brain, and methods to reversibly open the BBB in a targeted fashion to promote localized uptake of drugs to sites of neuropathology. Another exploratory project is developing an Alzheimer’s-on-Chip model to study the role of the BBB in Alzheimer’s Disease. The Brain Targeting Program is part of the Ingber lab’s Bioinspired Therapeutics and Diagnostics platform, which includes more than 20 Organ-on-Chip models and related projects. The group is collaborative and collegial and has extensive interactions between projects, people, and institutions.

    The mission of the Wyss Institute for Biologically Inspired Engineering at Harvard University is to transform human healthcare and the environment by emulating the engineering principles found in nature. Developed as an alliance between Harvard and other premier academic and clinical partner institutions, Institute faculty and staff collaborate in high-risk, fundamental research, and science-driven technology development. A major focus of the Institute is to translate the technologies developed by its faculty and staff into commercial products and therapies through collaborations with clinical investigators and establishment of corporate alliances and launching startup companies. For more information, visit: http://wyss.harvard.edu/.

    We seek outstanding postdoctoral applicants with expertise and/or interest in problem-driven research, targeted delivery, therapeutic/diagnostic discovery, BBB biology and its transport mechanisms, and biomarker discovery to join our interdisciplinary team of biologists and engineers. Applicants are expected to hold a Ph.D. or M.D. and have a record of high-quality publications in relevant fields. Strong interest in contributing to multidisciplinary teams that include engineers, biologists, physiologists, drug developers, and others is critical for this position. The ideal candidate would bring expertise in transcriptomic and proteomic research, biomarker discovery, BBB transport, and nanocarrier engineering, with interest in applying this expertise towards the development of novel brain transport approaches and therapeutics. The successful candidate will be responsible for leading brain transport and target discovery efforts, and exploring new methods to transport drugs using the new targets. The candidate will be expected to work independently under the mentorship of senior staff scientists and faculty to design experiments, learn new skills, troubleshoot, take scientific leadership of a significant part of the project, and train junior researchers. In addition, the candidate must function well in a team-oriented environment with other scientists and researchers at the Institute as well as external collaborators.

    Applications, assembled as single PDF files, should contain a complete resume, cover letter describing research interests and goals, full list of publications, copies of up to three relevant scientific papers, and the names and contact information of three references, who may be asked to provide letters of recommendation. Applications should be sent to faculty_postdocs@wyss.harvard.edu using the subject line “BRAIN TARGETING PROGRAM APPLICATION”.

    Harvard University is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law.

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