- Multimedia Type
- Focus Areas
- 3D Organ EngineeringHighly functional, multiscale, vascularized organ replacements that can be seamlessly integrated into the body.
- Adaptive Material TechnologiesSustainable, biomimetic building materials that respond to environmental cues like living organisms.
- Bioinspired Soft RoboticsSoft robotic systems that technologies that move, adapt, and seamlessly integrate with the human body.
- Bioinspired Therapeutics & DiagnosticsTherapeutic discovery and diagnostics development enabled by microsystems engineering, molecular engineering, computational design, and organ-on-a-chip in vitro human experimentation technology.
- Diagnostics AcceleratorAn initiative enabling the creation of new diagnostic technologies that solve high-value clinical problems through deep collaboration between the Wyss Institute and Brigham and Women’s Hospital. Candidate diagnostics will be driven by clinicians’ unmet needs, advanced in the Wyss Institute’s biomarker discovery and technology development labs, and validated in BWH’s CLIA lab, providing crucial clinical data to move them from the bench to the bedside faster.
- Immuno-MaterialsMaterial-based systems capable of modulating immune cells ex vivo and in the human body to treat or diagnose disease.
- Living Cellular DevicesRe-engineered living cells and biological circuits as programmable devices for medicine, manufacturing, and sustainability.
- Molecular RoboticsSelf-assembling nucleic acid molecules that can be programmed like robots to carry out specific tasks at the nanoscale without requiring power.
- Synthetic BiologyBreakthrough approaches to reading, writing, and editing nucleic acids and proteins for multiple applications, varying from healthcare to data storage.
- Technology Areas
- 3D Printing
- Building Materials
- Cell Therapy
- Disease Model
- DNA Nanostructures
- Drug Development
- Filtration & Separation
- Gene Circuits
- Medical Devices
- Organs on Chips
- Surface Coatings
- Wearable Devices
- Cell Biology
- Chemical Engineering
- Computer Science
- Electrical Engineering
- Genome Engineering
- Immune Engineering
- Materials Science
- Mechanical Engineering
- Polymer Chemistry
- Regenerative Medicine
- Self Assembly
- Stem Cell Engineering
- Synthetic Biology
- Tissue Engineering
- Application Areas
- Balance & Motor Control
- Brain Disease
- Drug Development
- Fundamental Research
- Heart Disease
- Infectious Disease
- Inflammatory Diseases
- Intestinal Disease
- Kidney Disease
- Liver Disease
- Lung Disease
- Motor Control
- Personalized Medicine
- Targeted Drug Delivery
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Video/AnimationCreating Scientific Marvels that are Works of ArtDuring his TEDx talk, Don Ingber shares his personal path from an ‘Aha’ moment in an undergraduate art class that led to his discovery of how living cells are constructed to his most recent breakthrough – a Human Body-On-Chips – which promises to replace animal testing and advance personalized medicine. Don’s work breaks down boundaries...
Video/AnimationThe Human Mind and Gait ControlResearchers study how our brains adjust to changes in our walking strides, gaining insights that could be used to develop better physical rehabilitation programs. Credit: Wyss Institute
Video/AnimationCogniXense: Speeding Up Treatments for Rare DiseasesAt the Wyss Institute, we are tackling Rett syndrome, a rare disease that affects 1 out of 9,000 children, by developing a scalable model for neurodevelopmental and cognitive diseases. This model can test drugs to see which will improve memory, learning, and behavior, with the end goal of finding effective therapies. Credit: Wyss Institute at...
Video/AnimationSoft Robotic Gripper for Jellyfish 2.0Scientists from the Wyss Institute at Harvard University and CUNY have created ultra-soft robotic grippers that resemble fettuccini noodles to safely catch and release delicate underwater creatures like jellyfish without harm. Credit: Wyss Institute at Harvard University
Video/AnimationImproving Canine HealthspanA Wyss Institute technology that can treat multiple age-related diseases is now being developed by Rejuvenate Bio into a treatment for mitral valve disease and other deadly conditions in dogs, with the goal of helping man’s best friend live longer, healthier lives. Credit: Wyss Institute at Harvard University
Video/AnimationInterrogator: Human Organ-on-ChipsThis video describes the “Interrogator” instrument that can be programmed to culture up to 10 different Organ Chips and sequentially transfer fluids between their vascular channels to mimic normal human blood flow between the different organs of our body. Its integrated microscope enables the continuous monitoring of the tissues’ integrities in the individual organ chips...
Video/AnimationImpact Through Disruptive InnovationAt the Wyss Institute, we leverage insights into how Nature builds, controls and manufactures to develop disruptive technology solutions for healthcare and the environment. Our innovations make an impact in the world through commercialization by new startups and corporate alliances. Learn more about technology translation at the Wyss Institute. Credit: Wyss Institute at Harvard University
Video/AnimationAAV Capsid EngineeringWyss researchers have created a high-throughput platform to generate an Adeno-associated virus 2 (AAV2) library containing 200,000 variants, each carrying a distinct mutation in the virus capsid protein. Their analysis identified capsid changes that enhanced “homing” potential to specific organs in mice and virus viability, as well as a new protein hidden in the capsid-encoding...
Video/AnimationeRAPID: a Platform for Portable DiagnosticseRapid is an electrochemical sensing platform that uses a novel antifouling coating to enable low-cost, multiplexed detection of a wide range of biomolecules for diagnostics and other applications. Credit: Wyss Institute at Harvard
Video/AnimationDesign Talk | Wyss Institute SelectsThe beauty of natural forms and their underlying design principles provide living organisms with their incredible strength, resilience, and efficiency. Matilda McQuaid, Deputy Director of Curatorial and Head of Textiles leads a discussion with Don Ingber, founding director of the Wyss Institute for Biologically Inspired Engineering at Harvard University, and his co-faculty member Pamela Silver....
Video/AnimationVoxelated Soft Matter via Multimaterial, Multinozzle 3D PrintingMultimaterial Multinozzle 3D (MM3D) Printing, a new technique developed by engineers at the Wyss Institute and Harvard SEAS, allows seamless switching between up to eight different materials within a single nozzle, allowing for the creation of complex 3D objects in a fraction of the time required by other extrusion-based 3D printing methods. Credit: Wyss Institute...
Video/AnimationRapid Triage Test for Active Pulmonary TuberculosisThere’s a large unmet need for accurate, fast, and inexpensive diagnostics for active tuberculosis (ATB), which claims the lives over a million people per year. A team of researchers from the Wyss Institute for Biologically Inspired Engineering, The Broad Institute of Harvard and MIT, Brigham and Women’s Hospital (BWH), and several other collaborating institutions have...