- Multimedia Type
- Focus Areas
- 3D Organ EngineeringHighly functional, multiscale, vascularized organ replacements that can be seamlessly integrated into the body.
- Adaptive Material TechnologiesSustainable, biomimetic building materials that respond to environmental cues like living organisms.
- Bioinspired Soft RoboticsSoft robotic systems that technologies that move, adapt, and seamlessly integrate with the human body.
- Bioinspired Therapeutics & DiagnosticsTherapeutic discovery and diagnostics development enabled by microsystems engineering, molecular engineering, computational design, and organ-on-a-chip in vitro human experimentation technology.
- Diagnostics AcceleratorAn initiative enabling the creation of new diagnostic technologies that solve high-value clinical problems through deep collaboration between the Wyss Institute and Brigham and Women’s Hospital. Candidate diagnostics will be driven by clinicians’ unmet needs, advanced in the Wyss Institute’s biomarker discovery and technology development labs, and validated in BWH’s CLIA lab, providing crucial clinical data to move them from the bench to the bedside faster.
- Immuno-MaterialsMaterial-based systems capable of modulating immune cells ex vivo and in the human body to treat or diagnose disease.
- Living Cellular DevicesRe-engineered living cells and biological circuits as programmable devices for medicine, manufacturing, and sustainability.
- Molecular RoboticsSelf-assembling nucleic acid molecules that can be programmed like robots to carry out specific tasks at the nanoscale without requiring power.
- Synthetic BiologyBreakthrough approaches to reading, writing, and editing nucleic acids and proteins for multiple applications, varying from healthcare to data storage.
- Technology Areas
- 3D Printing
- Building Materials
- Cell Therapy
- Disease Model
- DNA Nanostructures
- Drug Development
- Filtration & Separation
- Gene Circuits
- Medical Devices
- Organs on Chips
- Surface Coatings
- Wearable Devices
- Cell Biology
- Chemical Engineering
- Computer Science
- Electrical Engineering
- Genome Engineering
- Immune Engineering
- Materials Science
- Mechanical Engineering
- Polymer Chemistry
- Regenerative Medicine
- Self Assembly
- Stem Cell Engineering
- Synthetic Biology
- Tissue Engineering
- Application Areas
- Balance & Motor Control
- Brain Disease
- Drug Development
- Fundamental Research
- Heart Disease
- Infectious Disease
- Inflammatory Diseases
- Intestinal Disease
- Kidney Disease
- Liver Disease
- Lung Disease
- Motor Control
- Personalized Medicine
- Targeted Drug Delivery
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Video/AnimationSmart Thermally Actuating TextilesSmart Thermally Actuating Textiles (STATs) are tightly-sealed pouches that are able to change shape or maintain their pressure even in environments in which the exterior temperature or airflow fluctuates. This soft robotics technology could be developed as novel components of rehabilitation therapies or to prevent tissue damage in hospital bed or wheelchair-bound individuals. Credit: Wyss...
Video/AnimationOMNIVAX: Infection Vaccine PlatformThis video explains how OMNIVAX – an immuno-material-based vaccine technology can be used to rapidly create injectable vaccines against diverse viral and bacterial pathogens, and how the platform is used by the team to develop a vaccine against recurring urinary tract infections (UTIs) in their lead human application. Credit: Wyss Institute at Harvard University.
Video/AnimationBeating Back the Coronavirus: FDA-Approved Drug Repurposing PipelineWith the goal of rapidly repurposing FDA-approved drugs to treat COVID-19, the Wyss Institute is collaborating with the Frieman Lab at the University of Maryland Medical School and the tenOever Lab at the Icahn School of Medicine at Mount Sinai to establish a multidisciplinary pipeline that can rapidly predict, test, and validate potential treatments. Credit:...
Video/AnimationAlginate Hydrogel for AngiogenesisThis video describes how an alginate hydrogel can be used to trigger the formation of new blood vessels at an ischemic site in the body. Credit: Wyss Institute at Harvard University.
Video/AnimationLow-cost Tactile Displays for the Blind and Visually ImpairedElectrical Engineer, Michael Karpelson, presents a Wyss Institute Validation Project that is developing a simple and inexpensive tactile display technology for the blind and visually impaired, that has almost no learning curve and can augment alphanumerical displays in existing devices. Credit: Wyss Institute at Harvard University
Video/AnimationBeating Back the Coronavirus: Face Shields for Frontline Healthcare WorkersThere is a national shortage of personal protective equipment (PPE) for frontline healthcare workers battling the COVID-19 pandemic. Researchers from the Jennifer Lewis Lab at the Harvard School of Engineering and Applied Sciences and Wyss Institute at Harvard University self-assembled into a team manufacturing greatly needed face shields for local hospitals. Credit: Wyss Institute at...
Video/AnimationEnzymatic DNA Synthesis (EDS) for Data StoragePostdoctoral Fellow, Henry Lee, presents a Wyss Institute Validation Project that is developing a sustainable, low-cost approach for writing large amounts of digital information in DNA. This could one day replace current data storage methods, which are energy intensive and use large amounts of nonrenewable resources. Credit: Wyss Institute at Harvard University
Audio/PodcastTalking Techniques: Donald Ingber: How COVID-19 is changing conservatism in life sciences (Part 2)Following on from part 1 of this interview with the Founding Director of the Wyss Institute, Donald Ingber discusses the reasons he thinks organ-on-a-chip technologies are yet to be widely implemented in research. Expanding on elements of conservatism rooted in certain aspects of the life sciences, Donald explores how the scientific response to the current COVID-19 pandemic is challenging entrenched...
Video/AnimationBeating Back the CoronavirusWhen the coronavirus pandemic forced Harvard University to ramp down almost all on-site operations, members of the Wyss Institute community refocused their teams, and formed new ones, in order to fight COVID-19 on its multiple fronts. These efforts include building new pieces of personal protective equipment that were delivered to frontline healthcare workers, developing new...
Video/AnimationeRapid: Bringing Diagnostics HomeSenior Research Scientist, Pawan Jolly, gives an overview of the eRapid Institute Project, a platform of multiplexed electrochemical sensors for fast, accurate, portable diagnostics. Credit: Wyss Institute at Harvard University
Audio/PodcastLab Notes #1 | A wearable diagnostic for COVID-19The Allen Institute is dedicated to answering some of the biggest questions in bioscience and accelerating research worldwide. They are a recognized leader in large-scale research with a commitment to openly sharing their data, tools and knowledge with scientists around the world. In the first episode of their podcast Lab Notes, they interview Wyss Core...
Audio/PodcastTalking Techniques: COVID-19, Organ Chips and the Wyss Institute (Part 1)In the first installment of this two-part episode with Donald Ingber, Founding Director of the Wyss Institute (MA, USA), we discuss his invention of organ-on-a-chip technology, how he is utilizing them in the fight against COVID-19 and the Wyss Institute’s response to the pandemic. Donald touches on the performance of the much-discussed chloroquine in his...