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10 Results for 'Research and Technology Development'

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  • Research Assistant III – Microfluidic Cell Based Assays
    Research and Technology Development

    We are seeking a research assistant that will significantly contribute to a research program involving the use of cell culture and microfluidic in vitro models to support our efforts in novel drug discovery for multiple organs, including the liver. The successful candidate will be a part of the Bioinspired Therapeutics and Diagnostics platform and will be responsible for the testing potential drugs in 2D and 3D primary cell culture models, as well as develop and validate of various in-vitro and cell-based assays, including, but not limited to cell based qPCR/TaqMan, ELISA, westerns, enzymatic assays, imaging, and flow cytometry. [50522BR]

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  • Research Assistant III- Lung Disease
    Research and Technology Development

    We are seeking a Research Assistant III to significantly contribute to a research program involving the use of microfluidic human lung in vitro models to the pathology of cystic fibrosis, and the contribution of infection within this model. The successful candidate will be a part of our Bioinspired Therapeutics and Diagnostics Platform and also work with our internal drug discovery team to leverage this knowledge to identify and develop novel anti-inflammatory therapies. They will be responsible for the optimization and execution of microfluidic Organ on Chip primary cell culture, bacterial infection, and the development and validation of various in-vitro cell based assays, including, but not limited to, bacterial and cell based qPCR/TaqMan, ELISA, westerns, enzymatic assays, imaging, and immune cell-based assays. Previous experience with mammalian cell culture is a must. [50520BR ]

     

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  • Staff Scientist- Tissue and Organ Regeneration
    Research and Technology Development

    We are seeking a talented energetic professional to join our community as a Staff Scientist in the field of Tissue and Organ Regeneration. This entrepreneurially minded individual will work closely with Wyss Faculty and act as an intellectual “bridge” scientist, who will bring both tissue engineering bench expertise and industry/startup experience in product development to the table, and combine these strengths to drive basic science findings from your future colleagues at Harvard, MIT, and Boston University into pre-clinical animal models, and eventually to patients. The Staff Scientist will lead and participate in ongoing initiatives towards the goal of whole organ bioengineering at the Wyss Institute. With strong technical guidance from leaders in the field of 3D Organ Engineering, the Staff Scientist will develop and perform a broad range of research activities and procedures. [50647BR]

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  • Senior Staff Scientist – Machine Learning
    Research and Technology Development

    We are seeking a Senior Staff Scientist with extensive experience in machine learning, deep learning, and big data analysis to join our emerging Machine Intelligence and Data Analytics group, under the direction of Wyss leadership and faculty. This individual will work closely with experimental collaborators at the institute to effectively support their needs for data processing and interpretation, as well as developing strong relationships with the business development and technology translation teams. They will use computational approaches to integrate results from diverse high-throughput assay types, build predictive models for biomedicine applications including but not limited to electronic medical record mining, medical devices, drug discovery, and disease biology. [50500BR]

     

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  • Research Assistant III- Biology/Hematology
    Research and Technology Development

    We are seeking a motivated Research Assistant to work in biology and hematology within our Biomimetic Microsystems platform. The candidate will be a part of a multidisciplinary team working on developing a number of state-of-the-art processes to improve the hemocompatiblity of medical device materials and to separate pathogens from infected blood. The candidate will be responsible for performing experiments with blood to determine hemocompatibility of the materials both in vitro and in vivo, immunoassays (ELISAs), microscopy, histology, flow Cytometry and molecular biology as well as assay development. In vivo studies will involve evaluating the biocompatibility and efficacy of materials in Swine. In addition, the candidate will perform surface modification of medical devices and protein conjugation in order to characterize biocompatibility of devices and efficacy of pathogen separation. The position will require the candidate to work in a multidisciplinary team of biologists, chemists and engineers, interact in a collegial and fluid manner with other scientists and staff at the Wyss Institute, present his/her work at weekly meetings and write appropriate scientific articles and patent applications. [50128BR]

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