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We are looking for a research assistant to join the Intestine and Immune Organs on Chip team in Dr. Don Ingber’s laboratory. We are using immune organs-on-chip to study vaccines, solid tumors, and Lyme Disease. We are using Intestine Organ on Chip to study and model the intestinal tract and microbiome and its influences on diseases, such as malnutrition-associated with environmental enteric dysfunction (EED), inflammatory bowel disease (IBD), and radiation-induced injury, as well as therapeutic responses. With our work, we hope to understand what makes a vaccine effective, create an implantable therapy for pancreatic cancer, as well as incubate a startup that will design novel Lyme Disease therapeutics. Furthermore, the organ-chip model of intestinal injuries will help us to understand the molecular, genetic and nutritional bases of the disease and the testing of candidate therapeutics for it.

Reporting to the Principal Scientist leading the team, you will support these studies with the potential to become the go-to person for specific aspects of these research projects. You will learn cutting-edge human immunology and organ-on-chip techniques and may also be exposed to gene editing technology. The ideal candidate is comfortable learning and doing different types of tasks within the same week, has had diverse research experiences, and works well within a team. [65468BR]

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Reporting to the Senior Scientist II, you will contribute to the discovery effort that combines genetic and small molecule screening with human Organ Chips. As a member of the Advanced Technology team, you will be exposed to many different technologies in areas ranging from therapeutics and diagnostics to synthetic biology and material science, with the goal of identifying new product solutions and the unique potential opportunity to follow your passion either at the Institute or as a future co-founder of a Wyss start-up. [65615BR]

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We are looking for a research assistant to join the Intestine and Immune Organs on Chip team in Dr. Don Ingber’s laboratory. We are using immune organs-on-chip to study vaccines, solid tumors, and Lyme Disease. We are using Intestine Organ on Chip to study and model the intestinal tract and microbiome and its influences on diseases, such as malnutrition-associated with environmental enteric dysfunction (EED), inflammatory bowel disease (IBD), and radiation-induced injury, as well as therapeutic responses. With our work, we hope to understand what makes a vaccine effective, create an implantable therapy for pancreatic cancer, as well as incubate a startup that will design novel Lyme Disease therapeutics. Furthermore, the organ-chip model of intestinal injuries will help us to understand the molecular, genetic and nutritional bases of the disease and the testing of candidate therapeutics for it.

Reporting to the Principal Scientist leading the team, you will support these studies with the potential to become the go-to person for specific aspects of these research projects. You will learn cutting-edge human immunology and organ-on-chip techniques and may also be exposed to gene editing technology. The ideal candidate is comfortable learning and doing different types of tasks within the same week, has had diverse research experiences, and works well within a team. [65460BR]

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We are looking for a Research Assistant III to join our Diagnostics Accelerator initiative. You will work with a multidisciplinary team on developing RNA-based technologies for investigating pathological states from human biofluids. You will lead development of novel Next Generation Sequencing (NGS) experimental and computational methods that will be used across different diseases. Although you will work within a team and receive significant experimental and computational training, you will also have significant opportunities for scientific independence, and previous RAs working with us have contributed to multiple publications and presented their work at international conferences. [65463BR]

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We are looking for an enthusiastic and talented individual with previous experience in immunology to join the Bioinspired Therapeutics & Diagnostics platform as a senior and independent Research Assistant. You will significantly contribute to research programs on infectious disease vaccines, post-infection chronic illness and cancer immunology funded by the Gates Foundation, BARDA, ARPA-H and Northpond Ventures. You will work with primary immune cells derived from human blood, tonsils or other tissues, and be responsible for independently planning and executing scientific research involving microfluidic Organ on Chip primary cell culture as well as attenuated laboratory poliovirus strains or other biosafety level 2 pathogens. You will also develop and validate various in-vitro cell based assays. You will be expected to work independently with minimal guidance from academic staff to design experiments, learn new skills, troubleshoot, and to contribute intellectually to the project. [65462BR]

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We are looking for a motivated Research Assistant II to contribute to a multidisciplinary portfolio of research projects involving procedures of health monitoring, injections, blood sampling, survival surgery, post-operative care, and behavioral studies relating to projects on the Synthetic Biology Platform.

Reporting to the Director of Veterinary Services in coordination with Principal Scientist on the Synthetic Biology Platform at the Wyss Institute, you will be responsible for overseeing study animals, daily rounds, and observations to check animal health status; adherence to protocols and techniques at the animal facility; and performing and documenting experimental observations in rodent species. [65426BR]

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We are looking for a highly motivated clinical research coordinator to support the clinical studies at the Wyss Institute and across our collaborating institutions. Reporting to the Director of Clinical Research, you will be responsible for coordinating clinical studies and trials. [65367BR]

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The Wyss Institute is seeking a Scientist I to drive a discovery effort that combines genetic (e.g., CRISPR or shRNA-based) and small molecule screening with human Organ Chips. The goal is to identify therapeutic targets and candidate drugs that mitigate injury or accelerate healing after ionizing radiation exposure. While effective radiation countermeasures are needed for medical and military defense situations, there are few FDA-approved drugs for this indication. We are aiming to add to that list. This is an important role in a fast-paced multi-year translational and collaborative project that spans the lung, intestine, bone marrow, and immune Organ Chips. [64939BR]

 

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