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  • Staff Scientist – Stem Cell Engineering
    Research and Technology Development

    We are seeking a talented, enthusiastic, and experienced individual to work as part of the Synthetic Biology platform in the Advanced Technology Team. This position is an exciting opportunity to combine cutting edge, hands-on research with the strategic considerations of technology translation and product development. They will be responsible for developing technology relating to gene editing and engineering of stems cells and tissue-like structures/organoids. With an initial emphasis towards cerebral organoids, the individual will focus both on improving methodology for the creation of organoids as well as pursuing new commercial applications of them. [51071BR]

     

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  • Senior Staff Scientist – Diagnostic Accelerator
    Research and Technology Development

    We are seeking a talented energetic professional to join our community as a Senior Staff Scientist as part of the newly established Diagnostic Accelerator Team. This entrepreneurially minded individual will work closely with Wyss Faculty and act as an intellectual ‘bridge’ scientist, who will bring both biomarker development expertise and industry/startup experience in product development for diagnostics. The successful candidate will combine these strengths to translate basic science findings from your future colleagues at Harvard, MIT, other Boston area Universities and the Hospitals into robust diagnostic tools that enable improved clinical decision-making. The Senior Staff Scientist will be part of the Advanced Technology Team and will serve as a team lead in the area of Diagnostics. [50958BR]

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  • Embedded Systems Engineer
    Research and Technology Development

    We are seeking an enthusiastic individual to contribute to the design and construction of embedded electrical systems, instrumentation, and components for wearable robotic applications. Reporting to the Staff Lead and Faculty PI, the Staff Embedded Systems Hardware/Firmware Engineer will work with a team of engineers, researchers, designers, and clinicians to drive the innovation, evolution, and maintenance of a broad set of electrical systems. Their work will enable the team’s research, product development, and technology translation efforts. The role will involve collaborative projects within Harvard and other premier academic and clinical partner institutions that focus on high-risk, fundamental research and science-driven technology development. A major focus of our group is to translate the technologies into commercial products through industry partnerships and start-up companies. [50805BR]

     

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  • Research Assistant II – Microbial Culture
    Research and Technology Development

    We are seeking a talented, enthusiastic Research Assistant with experience working with microbes and bacteria and associated knowledge of a biosafety level 2 laboratory and has knowledge of microbiology and biochemistry as they relate to bacteria, yeast, and fungi. The candidate will be expected to isolate and maintain cultures of bacteria or other microorganisms such as algae, fungi, and some types of parasites, of both pathogenic and non-pathogenic abilities. The ability to work with microscopes, analytical balances, biological safety cabinets, and filtration manifolds is a plus. The person must be able to adhere to sterile technique and good lab practices. This person will maintain tissue culture facilities including daily maintenance of tissue culture equipment such as hoods, incubators, and water baths. They will also order supplies, maintain general stock and ensure the facilities kept clean and to environmental and health standards. [50665BR]

     

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  • Research Assistant III – Microfluidic Cell Based Assays
    Research and Technology Development

    We are seeking a research assistant that will significantly contribute to a research program involving the use of cell culture and microfluidic in vitro models to support our efforts in novel drug discovery for multiple organs, including the liver. The successful candidate will be a part of the Bioinspired Therapeutics and Diagnostics platform and will be responsible for the testing potential drugs in 2D and 3D primary cell culture models, as well as develop and validate of various in-vitro and cell-based assays, including, but not limited to cell based qPCR/TaqMan, ELISA, westerns, enzymatic assays, imaging, and flow cytometry. [50522BR]

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  • Research Assistant III- Lung Disease
    Research and Technology Development

    We are seeking a Research Assistant III to significantly contribute to a research program involving the use of microfluidic human lung in vitro models to the pathology of cystic fibrosis, and the contribution of infection within this model. The successful candidate will be a part of our Bioinspired Therapeutics and Diagnostics Platform and also work with our internal drug discovery team to leverage this knowledge to identify and develop novel anti-inflammatory therapies. They will be responsible for the optimization and execution of microfluidic Organ on Chip primary cell culture, bacterial infection, and the development and validation of various in-vitro cell based assays, including, but not limited to, bacterial and cell based qPCR/TaqMan, ELISA, westerns, enzymatic assays, imaging, and immune cell-based assays. Previous experience with mammalian cell culture is a must. [50520BR ]

     

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  • Staff Scientist- Tissue and Organ Regeneration
    Research and Technology Development

    We are seeking a talented energetic professional to join our community as a Staff Scientist in the field of Tissue and Organ Regeneration. This entrepreneurially minded individual will work closely with Wyss Faculty and act as an intellectual “bridge” scientist, who will bring both tissue engineering bench expertise and industry/startup experience in product development to the table, and combine these strengths to drive basic science findings from your future colleagues at Harvard, MIT, and Boston University into pre-clinical animal models, and eventually to patients. The Staff Scientist will lead and participate in ongoing initiatives towards the goal of whole organ bioengineering at the Wyss Institute. With strong technical guidance from leaders in the field of 3D Organ Engineering, the Staff Scientist will develop and perform a broad range of research activities and procedures. [50647BR]

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  • Senior Staff Scientist – Machine Learning
    Research and Technology Development

    We are seeking a Senior Staff Scientist with extensive experience in machine learning, deep learning, and big data analysis to join our emerging Machine Intelligence and Data Analytics group, under the direction of Wyss leadership and faculty. This individual will work closely with experimental collaborators at the institute to effectively support their needs for data processing and interpretation, as well as developing strong relationships with the business development and technology translation teams. They will use computational approaches to integrate results from diverse high-throughput assay types, build predictive models for biomedicine applications including but not limited to electronic medical record mining, medical devices, drug discovery, and disease biology. [50500BR]

     

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  • Research Assistant III- Biology/Hematology
    Research and Technology Development

    We are seeking a motivated Research Assistant to work in biology and hematology within our Biomimetic Microsystems platform. The candidate will be a part of a multidisciplinary team working on developing a number of state-of-the-art processes to improve the hemocompatiblity of medical device materials and to separate pathogens from infected blood. The candidate will be responsible for performing experiments with blood to determine hemocompatibility of the materials both in vitro and in vivo, immunoassays (ELISAs), microscopy, histology, flow Cytometry and molecular biology as well as assay development. In vivo studies will involve evaluating the biocompatibility and efficacy of materials in Swine. In addition, the candidate will perform surface modification of medical devices and protein conjugation in order to characterize biocompatibility of devices and efficacy of pathogen separation. The position will require the candidate to work in a multidisciplinary team of biologists, chemists and engineers, interact in a collegial and fluid manner with other scientists and staff at the Wyss Institute, present his/her work at weekly meetings and write appropriate scientific articles and patent applications. [50128BR]

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  • Research Assistant III-Biosensors and Microfluidics
    Research and Technology Development

    We are seeking a Research Assistant to work on research projects involving electrochemical and optical assay development, sensor fabrication and integration into novel diagnostic platforms that will address the following points: (i) Microfabrication of devices (ii) low sample volume consumption, (iii) rapid sample-to-results and (iv) high-throughput. Specifically, microfluidics and the integration of multiple and multiplexed sensitive detection schemes into one device are the main challenges that will need to be addressed. The major work task would be to learn the micro fabrication techniques used within the group and Electro-chemical assay development. [50195BR]

     

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  • Research Assistant II – Biosensors and Diagnostics
    Research and Technology Development

    We are seeking a Research Assistant II who will work on research projects involving electrochemical assay development, sensor and microfluidic fabrication and integration into novel diagnostic platforms that will address the following point: (i) Microfabrication of devices (ii) low sample volume consumption, (iii) rapid sample-to-results and (iv) high-throughput. Specifically, microfluidics and the integration of multiple and multiplexed sensitive detection schemes into one device are the main challenges that will need to be addressed. The major work task would be to get up speed with micro fabrication techniques used within the group and Electrochemical/ optical assay development. [50198BR]

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  • Research Assistant II
    Research and Technology Development

    We are seeking an energetic, enthusiastic, and multi-talented individual to work as a Research Assistant II. The employee will construct expression plasmids, perform transient transfections into mammalian cells, perform immunofluorescence staining, store data, and perform preliminary data analysis. The employee will also maintain an organized collection of plasmids, mammalian cell lines, and data collection protocols suitable for transfer to others including outside agencies. The employee will present data at group meetings, assist in writing papers and monthly reports to funding agencies. The employee will attend in seminar series within the Wyss Institute and HMS and take part in the scientific and intellectual life of the lab, the Wyss Institute, and Harvard Medical School. [50111BR]

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  • Staff Scientist -Tissue and Organ Regeneration
    Research and Technology Development

    We are seeking a talented energetic professional to join our community as a Staff Scientist in the field of Tissue and Organ Regeneration. This entrepreneurially minded individual will work closely with Wyss Faculty and act as an intellectual ‘bridge’ scientist, who will bring both tissue engineering bench expertise and industry / startup experience in product development to the table, and combine these strengths to drive basic science findings from your future colleagues at Harvard, MIT, and Boston University into pre-clinical animal models, and eventually to patients. [49927BR]

     

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  • Research Scientist
    Research and Technology Development

    We are seeking a talented, enthusiastic and experienced individual to work in a team of Institute researchers and faculty as part of the Bioinspired Therapeutics & Diagnostics platform. This candidate will be working on projects involving the development of novel therapeutics. In collaboration with other team members, this position will be responsible for designing and carrying out screening and characterization experiments to identify novel antibodies, peptides, and formulations. The candidate will be responsible for designing and carry out molecular biology, protein design, antibody selections, and cell-based assays in our process. [49871BR]

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