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184 Results for 'Bioinspired Therapeutics & Diagnostics'
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Technologies 16
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Brain targeting of drugs and diagnostics
In its Brain Targeting Program, a Wyss team led by Founding Director Donald Ingber, M.D., Ph.D. and Staff Program Lead James Gorman, M.D., Ph.D. is developing improved approaches to target drugs and diagnostics to the brain. Leveraging the human blood-brain barrier (BBB) Chip technology developed by Ingber’s team, combined with advanced antibody R&D capabilities, the... -
Injectable Alginate Hydrogels for Medical Applications
One of the biggest challenges in medicine is getting a drug to the right part of the body at the right time. Even when the target site in the body is known, like a pain-causing injury or a cancerous tumor, most drugs are given as oral pills or intravenous infusions, which limits their effectiveness. In... -
Digital information storage in DNA
The genetic material DNA has garnered considerable interest as a medium for digital information storage because its density and durability are superior to those of existing silicon-based storage media. For example, DNA is at least 1000-fold more dense than the most compact solid-state hard drive and at least 300-fold more durable than the most stable... -
AquaPulse: Portable Off-the-Grid Water Purification
Globally, more than 2 billion people are forced to use a drinking water source that is contaminated with bacteria, parasites, and other pathogens, and an estimated 502,000 people die each year from diarrhea as a result of unsafe water. While a majority of the world has access to improved water sources, many are often contaminated;... -
CogniXense – A high-throughput cognitive screen for modeling disorders on-the-fly
There are more than 6,000 known single-gene disorders, in which a disruption to one gene out of the 20,000 in the human genome is enough to cause significant health effects. In order to study these disorders and develop treatments, a given genetic mutation must first be induced in a large number of animal models (usually... -
INSPECTR™: Direct-to-Consumer Molecular Diagnostic
Molecular diagnostics is the fastest growing segment of the global in vitro diagnostics market. There remains a gap, however, in providing this technology directly to consumers in a format that is as cost effective and as simple to use as a lateral flow immunoassay, like glucose and pregnancy tests. Scientists at the Wyss Institute have...
News 130
Multimedia 38
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Audio/PodcastDisruptive: Accelerating DiagnosticsIn this episode of Disruptive, Wyss Core Faculty member David Walt discusses his lessons learned from founding successful biotech companies and how he incorporates translation-minded thinking early on into his current diagnostic research in his labs at the Wyss Institute and the Brigham and Women’s Hospital. Walt and collaborators are inventing new diagnostic tools to... -
Video/AnimationHumans of the Wyss – Faculty Edition with Mike LevinOur interview series, “Humans of the Wyss – Faculty Edition,” features Wyss Institute faculty members discussing how they think about their work, the influences that helped shape them as scientists, and their collaborations at the Wyss Institute and beyond. In the second edition of the series, Benjamin Boettner, Wyss Institute Communications team member, talks to... -
Video/AnimationOrigami OrgansA multidisciplinary team of scientists, engineers, and architectural designers are developing Origami Organs that could function like artificial kidneys. Credit: Wyss Institute at Harvard University -
Audio/PodcastDisruptive: Art Advances ScienceIn this episode of Disruptive, Wyss Institute Founding Director Don Ingber and Staff Scientist Charles Reilly discuss their process creating The Beginning, a short film inspired by Star Wars, to better communicate science to the public…and how they made a scientific discovery along the way. To make The Beginning, film industry visual effects and animation... -
Video/AnimationTherapeutic Organ Engineering: Highlights From The 8th Annual Wyss SymposiumThe 8th Annual Wyss International Symposium focused on innovations in therapeutic organ engineering, featuring diverse speakers doing exciting work in 3D organ engineering, materials fabrication, and vascular integration. This video highlights some of the themes discussed in their presentations as well as the advances that are leading to the ultimate goals of developing new approaches... -
Video/AnimationScience On TapDuring this live studio recording of Science On Tap, Donald Ingber, M.D., Ph.D. will explain to host Graham Chedd why the name of the institute he heads at Harvard, the Wyss Institute for Biologically Inspired Engineering, nicely sums up its goal. Dr. Ingber’s stellar career has focused on turning nature’s solutions to engineering problems into...