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CogniXense for Rare Disease Drug Discovery
Unravel Biosciences has licensed a Wyss drug discovery platform technology to identify and create drugs to treat complex central nervous system disorders, starting with Rett syndrome.

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Beating Back the Coronavirus: FDA-Approved Drug Repurposing Pipeline
With the goal of rapidly repurposing FDA-approved drugs to treat COVID-19, the Wyss Institute is collaborating with the Frieman Lab at the University of Maryland Medical School and the tenOever Lab at the Icahn School of Medicine at Mount Sinai to establish a multidisciplinary pipeline that can rapidly predict, test, and validate potential treatments. Credit:...
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Interrogator: Human Organ-on-Chips
This video describes the “Interrogator” instrument that can be programmed to culture up to 10 different Organ Chips and sequentially transfer fluids between their vascular channels to mimic normal human blood flow between the different organs of our body. Its integrated microscope enables the continuous monitoring of the tissues’ integrities in the individual organ chips...
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Soft Fabric Sensors
This textile-based sensor effectively registers fine motor movements of the human body, taking researchers one step closer to creating soft, wearable robots. Credit: Wyss Institute at Harvard University
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Small Airway-on-a-Chip: Modeling COPD and Asthma
Development of new therapeutics for chronic lung diseases have been hindered by the inability to study them in vitro. To address this challenge, Wyss Institute researchers used their Organ-on-a-Chip technology to produce a microfluidic ‘human lung small airway-on-a-chip.’ The device, which is composed a clear rubber material, is lined by living Human lung small airway...
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Soft Robotic Exosuit
In this video, Harvard faculty member Conor Walsh and members of his team explain how the biologically inspired Soft Exosuit targets enhancing the mobility of healthy individuals and restoring the mobility of those with physical disabilities. This research is partially funded by the National Science Foundation. Note: This technology is currently in the research and...
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Bioinspired Approach to Sepsis Therapy
Wyss Institute Founding Director Don Ingber, Senior Staff Scientist Michael Super and Technology Development Fellow Joo Kang explain how they engineered the Mannose-binding lectin (MBL) protein to bind to a wide range of sepsis-causing pathogens and then safely remove the pathogens from the bloodstream using a novel microfluidic spleen-like device. Credit: Wyss Institute at Harvard...