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Technologies 1

• CogniXense for Rare Disease Drug Discovery
  Unravel Biosciences has licensed a Wyss drug discovery platform technology to identify and create drugs to treat complex central nervous system disorders, starting with Rett syndrome.

News 37

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• Press Release
  
  DARPA-ABC program supports Wyss Institute-led collaboration toward deeper understanding of anesthesia and safe drugs enabling anesthesia without the need for extensive monitoring
  January 15, 2025
• Press Release
  
  “Suspended animation” drug could aid organ transplantation and survival from traumatic injury
  September 24, 2024
• Press Release
  
  Wyss Institute team selected by DARPA-SHIELD program to develop first-of-its-kind biologically engineered broad-spectrum antimicrobial therapeutic
  September 16, 2024

Multimedia 6

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  Video/Animation
  Beating Back the Coronavirus: FDA-Approved Drug Repurposing Pipeline
  With the goal of rapidly repurposing FDA-approved drugs to treat COVID-19, the Wyss Institute is collaborating with the Frieman Lab at the University of Maryland Medical School and the tenOever Lab at the Icahn School of Medicine at Mount Sinai to establish a multidisciplinary pipeline that can rapidly predict, test, and validate potential treatments. Credit:...

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  Video/Animation
  Interrogator: Human Organ-on-Chips
  This video describes the “Interrogator” instrument that can be programmed to culture up to 10 different Organ Chips and sequentially transfer fluids between their vascular channels to mimic normal human blood flow between the different organs of our body. Its integrated microscope enables the continuous monitoring of the tissues’ integrities in the individual organ chips...

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  Video/Animation
  Soft Fabric Sensors
  This textile-based sensor effectively registers fine motor movements of the human body, taking researchers one step closer to creating soft, wearable robots. Credit: Wyss Institute at Harvard University

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  Video/Animation
  Small Airway-on-a-Chip: Modeling COPD and Asthma
  Development of new therapeutics for chronic lung diseases have been hindered by the inability to study them in vitro. To address this challenge, Wyss Institute researchers used their Organ-on-a-Chip technology to produce a microfluidic ‘human lung small airway-on-a-chip.’ The device, which is composed a clear rubber material, is lined by living Human lung small airway...

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  Video/Animation
  Soft Robotic Exosuit
  In this video, Harvard faculty member Conor Walsh and members of his team explain how the biologically inspired Soft Exosuit targets enhancing the mobility of healthy individuals and restoring the mobility of those with physical disabilities. This research is partially funded by the National Science Foundation. Note: This technology is currently in the research and...

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  Video/Animation
  Bioinspired Approach to Sepsis Therapy
  Wyss Institute Founding Director Don Ingber, Senior Staff Scientist Michael Super and Technology Development Fellow Joo Kang explain how they engineered the Mannose-binding lectin (MBL) protein to bind to a wide range of sepsis-causing pathogens and then safely remove the pathogens from the bloodstream using a novel microfluidic spleen-like device. Credit: Wyss Institute at Harvard...