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Technologies 2

• DNA Nanotechnology Tools: From Design to Applications
  A suite of diverse, multifunctional DNA nanotechnological tools with unique capabilities and potential for a broad range of clinical and biomedical research areas. Our DNA nanotechnology devices were engineered to overcome specific bottlenecks in the development of new therapies and diagnostics, and to help further our understanding of molecular structures.
• Multiplexed Molecular Force Spectroscopy
  Programmable DNA nanoswitches, invented at the Wyss Institute, can now be used in combination with a benchtop Centrifuge Force Microscope (CFM) as a highly reliable tool to observe thousands of individual molecules and their responses to mechanical forces in parallel. By analyzing the responses of single molecules under conditions where they experience such forces, it is possible...

News 12

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• Community
  
  The Wyss Institute’s 2022-2023 Validation Projects
  September 12, 2022
• Press Release
  
  Fingerprinting proteins with force
  October 21, 2021
• Research Spotlights
  
  DNA: From blueprint to blank slate
  April 23, 2021

Events 1

• Sep 21, 2018,
  8:15am - 6:15pm
  Wyss Event
  
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  Wyss Symposium 2018: Molecular Robotics
  The 9th International Wyss Symposium will focus on new advances in the emerging field of Molecular Robotics, with the goal of sharing recent progress at the intersection of DNA nanotechnology, synthetic biology, robotics, and computer science, that could lead to programmable molecular machines as novel solutions for research and medicine. This event is free, however... Free and open to public

Multimedia 3

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  Video/Animation
  DNA Nanoswitch Calipers
  The world’s tiniest ruler for biomolecules has been created by researchers at the Wyss Institute at Harvard University, Harvard Medical School, and Boston Children’s Hospital. DNA Nanoswitch Calipers can measure very small peptides to better understand their structure and function, and enable them to be quickly identified in mixed samples. These insights could lead to...

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  Audio/Podcast
  Disruptive: Molecular Robotics
  How can DNA be programmed to build novel structures, devices, and robots? We have taken our understanding of DNA to another level, beginning to take advantage of some of DNA’s properties that have served nature so well, but in ways nature itself may have never pursued. Humans can now use DNA as a medium for...

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  Video/Animation
  DNA Nanoswitches
  Gel electrophoresis, a common laboratory process, sorts DNA or other small proteins by size and shape using electrical currents to move molecules through small pores in gel. The process can be combined with novel DNA nanoswitches, developed by Wyss Associate Faculty member Wesley Wong, to allow for the simple and inexpensive investigation of life’s most...