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Technologies 1

• Multiplexed Molecular Force Spectroscopy
  Programmable DNA nanoswitches, invented at the Wyss Institute, can now be used in combination with a benchtop Centrifuge Force Microscope (CFM) as a highly reliable tool to observe thousands of individual molecules and their responses to mechanical forces in parallel. By analyzing the responses of single molecules under conditions where they experience such forces, it is possible...

News 6

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  Disruptive: Molecular Robotics
  May 9, 2016
• Press Release Democratizing high-throughput single molecule force analysis
  March 17, 2016
• Video/​Animation DNA Nanoswitches for Drug Discovery, and Beyond
  January 29, 2015

Multimedia 2

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  Audio/Podcast
  Disruptive: Molecular Robotics
  How can DNA be programmed to build novel structures, devices, and robots? We have taken our understanding of DNA to another level, beginning to take advantage of some of DNA’s properties that have served nature so well, but in ways nature itself may have never pursued. Humans can now use DNA as a medium for...

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  Video/Animation
  DNA Nanoswitches
  Gel electrophoresis, a common laboratory process, sorts DNA or other small proteins by size and shape using electrical currents to move molecules through small pores in gel. The process can be combined with novel DNA nanoswitches, developed by Wyss Associate Faculty member Wesley Wong, to allow for the simple and inexpensive investigation of life’s most...