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Technologies 1

• DNA Nanostructures for Drug Delivery
  Researchers at the Wyss Institute have developed two methods for building arbitrarily shaped nanostructures using DNA, with a focus on translating the technology towards nanofabrication and drug delivery applications. One proprietary nanofabrication technique, called “DNA-brick self-assembly,” uses short, synthetic strands of DNA that work like interlocking Lego® bricks. It capitalizes on the ability to program...

News 17

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• Research Spotlights
  
  i3 Center: Biomaterials to Create T Cell Immunity
  July 1, 2020
• Research Spotlights
  
  DNA nanostructures suit up for future missions
  February 21, 2020
• Research Spotlights
  
  Harnessing Nature to Beat Cancer
  February 28, 2019

Events 4

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• May 11 → 12, 2020 Symposium
  
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  Max Bergmann Symposium 2020
  The Max Bergmann Symposium 2020 will take place at the Steigenberger Hotel in the historic city center in Dresden, Germany. The meeting will include talks by leading scientists from around the world. The event aims to offer a cross-disciplinary perspective on molecular self-assembly and self-organization. The central topics are: Artificial systems: assembling synthetic molecules into well-defined nanostructures and supramolecular polymer materials....
• Oct 15, 2018,
  1:50pm - 5:15pm
  Symposium
  
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  KIST-DFCI Symposium
  Please join the Korea Institute of Science and Technology (KIST) and Dana-Farber Cancer Institute (DFCI) for a Symposium featuring presentations by Wyss Faculty members, David Mooney and Samir Mitragotri. David Mooney will present on biomaterials to build immunity and Samir Mitragotri will focus on synergistic drug combinations for cancer therapy. Fore more information or to... Free and open to public
• Sep 21, 2018,
  8:15am - 6:15pm
  Wyss Event
  
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  Wyss Symposium 2018: Molecular Robotics
  The 9th International Wyss Symposium will focus on new advances in the emerging field of Molecular Robotics, with the goal of sharing recent progress at the intersection of DNA nanotechnology, synthetic biology, robotics, and computer science, that could lead to programmable molecular machines as novel solutions for research and medicine. This event is free, however... Free and open to public

Multimedia 6

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  Audio/Podcast
  William Shih: Lego-Style Construction of Future Therapeutics From DNA
  Listen to Wyss Core Faculty member William Shih’s lecture on how custom molecular shapes can be designed using DNA building blocks and how these minuscule devices could have a profound impact on fields ranging from molecular biophysics to therapeutics to nano-optics for decades to come. Shih’s lecture is part of the ArtScience lecture series at...

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  Audio/Podcast
  Disruptive: Molecular Robotics
  How can DNA be programmed to build novel structures, devices, and robots? We have taken our understanding of DNA to another level, beginning to take advantage of some of DNA’s properties that have served nature so well, but in ways nature itself may have never pursued. Humans can now use DNA as a medium for...

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  Video/Animation
  Virus-inspired DNA Nanodevices
  Wyss Institute Core Faculty member William Shih and Technology Development Fellow Steven Perrault explain why DNA nanodevices need protection inside the body, and how a viral-inspired strategy helps protect them. Credit: Wyss Institute at Harvard University

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  Video/Animation
  Building 3D Structures with DNA Bricks
  The nanofabrication technique, called ‘DNA-brick self-assembly,’ uses short, synthetic strands of DNA that work like interlocking Lego bricks. It capitalizes on the ability to program DNA to form into predesigned shapes thanks to the underlying ‘recipe’ of DNA base pairs. This animation accurately shows how the DNA strands self assemble to build a structure.DNA Nanostructures...

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  Video/Animation
  DNA Bricks: Molecular Animation
  The nanofabrication technique, called ‘DNA-brick self-assembly,’ uses short, synthetic strands of DNA that work like interlocking Lego bricks. It capitalizes on the ability to program DNA to form into predesigned shapes thanks to the underlying “recipe” of DNA base pairs. Animation created by Digizyme for the Wyss Institute. Credit: Wyss Institute at Harvard University

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  Video/Animation
  Making Structures with DNA “Building Blocks”
  Researchers at the Wyss Institute have developed a method for building complex nanostructures out of short synthetic strands of DNA. Called single-stranded tiles (SSTs), these interlocking DNA “building blocks,” akin to Legos, can be programmed to assemble themselves into precisely designed shapes, such as letters and emoticons. Credit: Wyss Institute at Harvard University