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Technologies 1

• FeCILL: Targeted Treatment for Severe Fungal Infections
  FeCILL is novel delivery vehicle for antifungal drugs that targets them right to the infection site and reduces harmful side effects in patients with severe fungal infections.

Collaborations 2

• Brain Targeted Therapeutic Collaboration
  Combine our shuttles with your drugs to create new brain targeted therapeutics for patients.
• Brain Shuttle Research Sponsorship & Licensing
  Enabling brain-targeted drug development through non-exclusive licensing and pre-competitive research sponsorship.

News 12

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• Press Release
  
  DNA origami-based vaccines toward safe and highly-effective precision cancer immunotherapy
  March 15, 2024
• Video/​Animation
  
  The Wyss Brain Targeting Program is expanding its “neural network”
  January 25, 2024
• Community
  
  Neha Kapate on Backpacking her way into a New Frontier for Treating Incurable Diseases
  June 23, 2023

Multimedia 5

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  Video/Animation
  Genetic & Cellular Engineering w/ David Schaffer & Samir Mitragotri – BIOS Roundtable
  Samir Mitragotri is a Core Faculty member at the Wyss Institute and the Hiller Professor of Bioengineering & Hansjorg Wyss Professor of Biologically Inspired Engineering at Harvard SEAS. David Schaffer is Professor at UC Berkeley & Director at BBH. The two discuss Genetic and Cellular Engineering, with a focus on delivery challenges.

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  Video/Animation
  FeCILL: Reimagining How We Treat the Sickest Patients
  Opportunistic fungal infections usually only affect patients whose immune systems are compromised, but when they do, they are often deadly – the mortality rate for these infections can be as high as 25%. Existing antifungal treatments have high levels of toxicity, and can harm the patient more than they help. Researchers at the Wyss Institute...

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  Audio/Podcast
  BIOS Podcast – Future of Drug Delivery w/ Samir Mitragotri – Professor at Harvard, Core Faculty member at the Wyss Institute
  Samir Mitragotri is the Hiller Professor of Bioengineering and Hansjörg Wyss Professor of Biologically Inspired Engineering. Samir is an elected member of the National Academies of Engineering and Medicine, and elected fellow of the American Institute of Medical and Biological Engineering, the American Association for the Advancement of Science, the National Academy of Inventors, the...

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  Video/Animation
  Wyss Institute Brain Targeting Program
  This animation explains how Wyss Institute researchers and their industry partners aim to identify novel transport targets and shuttle compounds to enable more effective delivery of drugs to the brain. Credit: Wyss Institute at Harvard University.

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  Video/Animation
  Le Lab Presents: Designing Future Therapeutics with Samir Mitragotri
  Wyss Core Faculty member Samir Mitragotri, Ph.D. presented a talk at Le Laboratoire Cambridge on February 13th, 2019, titled Designing Future Therapeutics. Effective delivery of therapeutics is a major problem in today’s healthcare. At a fundamental level, the challenge of therapeutic delivery reflects the fact that the drug distribution in the body is limited by body’s...