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Video/Animation

Mucus Layer In Vitro on Human Colon Chip
Using Human Organ Chips, researchers at the Wyss Institute were able to generate the mucus layer of the colon in vitro, which has never been done before. In the colon, the mucus layer protects intestinal epithelial cells against inflammatory stimuli such as pathogens, damaged cells, or irritants. The ability to support mucus-producing cells is one...
Video/Animation

Beating Back the Coronavirus – COVID-19 detecting face mask
Using freeze-dried cell free reactions and CRISPR-based biosensors, researchers at the Wyss Institute and M.I.T. have created a face mask that can detect the SARS-CoV-2 virus in a wearer’s breath in under 90 minutes. Such a mask would allow medical professionals to quickly identify COVID-19 patients and begin effective treatments. This facemask is a proof-of-concept...
Video/Animation

Wearable Synthetic Biology – Clothing that can detect pathogens and toxins
What if we could create clothing that harnesses synthetic biology to detect the wearer’s exposure to toxins and pathogens? A team of researchers at the Wyss Institute and M.I.T. did just that byembedding freeze-dried, synthetic biology-based sensors into flexible materials and textiles. These sensors can detect pathogens such as the SARS-CoV-2 virus and toxins such...
Video/Animation

The Game-Changing Potential of mRNA Vaccines
Promising mRNA vaccines years ago emerged from early-stage development, only to stall before proving themselves in clinical trials. Pushed by pandemic urgency across the notorious “Valley of Death,” this platform vastly exceeded expectations and is now poised to transform the vaccine R&D landscape. During the early months of the historic rollout of COVID-19 vaccines, Sabin’s...
Video/Animation

Wyss Institute Brain Targeting Program
This animation explains how Wyss Institute researchers and their industry partners aim to identify novel transport targets and shuttle compounds to enable more effective delivery of drugs to the brain. Credit: Wyss Institute at Harvard University.
Video/Animation

Nature Can Help Us Prepare for the Next Pandemic
Resiliency, redundancy, adaptability: COVID-19 has shown humanity that we need more of the qualities that are built into nature. See how a cat’s tongue inspired Wyss Lead Staff Engineer Richard Novak to create a novel nasal swab design to aid in COVID-19 diagnostics.