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Video/Animation

Innovation Showcase – Wyss Institute: Wearable Technology with Biosensors
Jay Sugarman talks with Peter Nguyen Ph.D., Luis Soenksen, Ph.D., and Nina Donghia–all of whom are associated with the Wyss Institute for Biologically Inspired Engineering at Harvard University. They’re on Innovation Showcase to inform viewers about the groundbreaking research they and their colleagues have been involved with related to the development of wearable technology as...
Video/Animation

miSherlock – Detecting COVID-19 Variants from Saliva
Despite increasing vaccination rates, new, more-infectious variants of SARS-CoV-2 could prolong the COVID-19 pandemic. Researchers at the Wyss Institute at Harvard University and MIT have created a low-cost, CRISPR-based diagnostic platform that can detect SARS-CoV-2 variants in a patient’s saliva without the need for any additional equipment. The team hopes their device will enable more...
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Mucus Layer In Vitro on Human Colon Chip
Using Human Organ Chips, researchers at the Wyss Institute were able to generate the mucus layer of the colon in vitro, which has never been done before. In the colon, the mucus layer protects intestinal epithelial cells against inflammatory stimuli such as pathogens, damaged cells, or irritants. The ability to support mucus-producing cells is one...
Video/Animation

Beating Back the Coronavirus – COVID-19 detecting face mask
Using freeze-dried cell free reactions and CRISPR-based biosensors, researchers at the Wyss Institute and M.I.T. have created a face mask that can detect the SARS-CoV-2 virus in a wearer’s breath in under 90 minutes. Such a mask would allow medical professionals to quickly identify COVID-19 patients and begin effective treatments. This facemask is a proof-of-concept...
Video/Animation

Wearable Synthetic Biology – Clothing that can detect pathogens and toxins
What if we could create clothing that harnesses synthetic biology to detect the wearer’s exposure to toxins and pathogens? A team of researchers at the Wyss Institute and M.I.T. did just that byembedding freeze-dried, synthetic biology-based sensors into flexible materials and textiles. These sensors can detect pathogens such as the SARS-CoV-2 virus and toxins such...
Video/Animation

The Game-Changing Potential of mRNA Vaccines
Promising mRNA vaccines years ago emerged from early-stage development, only to stall before proving themselves in clinical trials. Pushed by pandemic urgency across the notorious “Valley of Death,” this platform vastly exceeded expectations and is now poised to transform the vaccine R&D landscape. During the early months of the historic rollout of COVID-19 vaccines, Sabin’s...
Video/Animation

Wyss Institute Brain Targeting Program
This animation explains how Wyss Institute researchers and their industry partners aim to identify novel transport targets and shuttle compounds to enable more effective delivery of drugs to the brain. Credit: Wyss Institute at Harvard University.
Video/Animation

Nature Can Help Us Prepare for the Next Pandemic
Resiliency, redundancy, adaptability: COVID-19 has shown humanity that we need more of the qualities that are built into nature. See how a cat’s tongue inspired Wyss Lead Staff Engineer Richard Novak to create a novel nasal swab design to aid in COVID-19 diagnostics.
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The electrical blueprints that orchestrate life | Michael Levin TED Talk
DNA isn’t the only builder in the biological world — there’s also a mysterious bioelectric layer directing cells to work together to grow organs, systems and bodies, says biologist and Wyss Associate Faculty member Michael Levin. Sharing unforgettable and groundbreaking footage of two-headed worms, he introduces us to xenobots — the world’s first living robots,...
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Wyss Lumineers: Class of 2020
On November 9th, 2020, Technology Translation Director Angelika Fretzen donned her biking boots and helmet to deliver jackets to the Wyss Institute’s Lumineers Class of 2020. Lumineers are entrepreneurs who successfully de-risk an innovative technology at the Wyss Institute and found a start-up company to commercialize it for real-world impact. Credit: Wyss Institute at Harvard...
Video/Animation

Using deep learning to detect cancerous skin lesions
Melanoma is a very severe cancer that is often diagnosed too late to save patients’ lives, and most people do not regularly visit a dermatologist for skin exams. Early-stage identification of suspicious pigmented lesions (SPLs), ideally by primary care providers, could lead to improved melanoma prognosis. Researchers at the Wyss Institute and MIT have developed...
Video/Animation

PhonoGraft: Programming the eardrum to repair itself
Eardrum perforations are a widespread problem affecting millions worldwide. Current standard of care is invasive, involves harvesting an autologous tissue to patch the eardrum, and often requires to revision surgeries, while hearing outcomes remain unsatisfying. What if we could program the eardrum to repair itself after injury? Researchers at the Wyss Institute, Massachusetts Eye and...