Sandy joined the Wyss Institute in 2023 as a staff scientist in the Immuno-Materials platform. Before joining the Wyss, Sandy played a pivotal role in the design, synthesis, and structural characterization of reticular biomaterials using multi-step synthesis techniques. Her doctoral research focused on developing copper-based Metal-Organic Frameworks (MOFs) and encapsulating them with bioactive phenolic compounds for targeted delivery in gastrointestinal cancers. To optimize drug loading, Sandy employed acid etching techniques to engineer the framework, creating a hierarchical porous structure capable of accommodating larger drug molecules while maintaining the overall integrity of the framework. Additionally, she improved the stability of the MOF crystal by growing copper-based nanoflowers onto the surface, resulting in a hierarchical core-shell nanocomposite. Sandy’s current research interests lie in exploring the inherent immunomodulatory properties of nanomaterials and their potential to regulate the immune response. She holds a B.S. in Clinical Research from Campbell University in North Carolina, an M.S. in Chemistry from the Purdue School of Science, and a Ph.D. in Chemistry from UAE University. During her academic journey, Sandy worked closely with Omar Yaghi’s group at the University of California, Berkeley, focusing on MOF and COF synthesis.
Sandy Elmehrath, Ph.D.
Scientist II