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Injectable Alginate Hydrogels for Medical Applications
One of the biggest challenges in medicine is getting a drug to the right part of the body at the right time. Even when the target site in the body is known, like a pain-causing injury or a cancerous tumor, most drugs are given as oral pills or intravenous infusions, which limits their effectiveness. In...
MAGE: Multiplex Automated Genomic Engineering
Developed at the Wyss Institute, the multiplex automated genome engineering (MAGE) technology harnesses the natural principles of evolution to do all the heavy lifting of genome design and automates these steps to dramatically shorten the time scale required to produce microbes with specialized functionalities for manufacturing, sensing and therapeutic applications. Genome engineering has a wide...
Video/AnimationCatalytic Nanoarchitectures for Clean AirThe Wyss Institute is developing a new type of coating for catalytic converters that, inspired by the nanoscale structure of a butterfly’s wing, can dramatically reduce the cost and improve the performance of air purification technologies, making them more accessible to all. Credit: Wyss Institute at Harvard University
Audio/PodcastBiofilms: Reprogramming Bacteria to Improve LivesWyss Core Faculty member Neel Joshi and Postdoctoral Fellow Anna Duraj-Thatte discuss the intersection between synthetic biology and materials science as an underexplored area with great potential to positively affect our daily lives—applications ranging from manufacturing to medicine. Dr. Joshi outlines ways that his lab at the Wyss Institute is looking at reprogramming bacteria in...
Video/Animation3D Printing Ceramic FoamThis video shows the 3D printing process that adds layer upon layer of the foam link to create a 3D porous ceramic honeycomb pattern. This new capability is an important step toward generating porous materials for lightweight structures, thermal insulation, tissue scaffolds and other applications. Credit: Lori Sanders
Video/AnimationBioprinting: The Kidney’s Proximal TubulesIn this video, see how the Wyss Institute team has advanced bioprinting to the point of being able to fabricate a functional subunit of a kidney. Credit: Wyss Institute at Harvard University
Video/AnimationOctobot: A Soft, Autonomous RobotThe Octobot is the first entirely soft, autonomous robot. It is made by a combination of embedded 3D printing, modeling, and soft lithography. Inspired by real octopuses, the Octobot has no rigid components. It is powered by a chemical reaction and controlled with a microfluidic logic that directs the flow of fuel. The logic circuit...
Video/AnimationToehold SwitchesIn this animation, Wyss Institute Postdoctoral Fellow Alex Green, Ph.D., the lead author of “Toehold Switches: De-Novo-Designed Regulators of Gene Expression”, narrates a step-by-step guide to the mechanism of the synthetic toehold switch gene regulator. Credit: Wyss Institute at Harvard University