Discipline: Nanotechnology
81 Results for 'Nanotechnology'
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Technologies 6
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Cellular “Backpacks” to Slow Tumor Growth
Macrophages are the body’s multipurpose defense agents, patrolling for pathogens and engulfing cellular debris, foreign substances, microbes, and even cancer cells. But cancerous tumors have evolved an insidious defense mechanism: they can switch arriving macrophages from an anti-cancer state to a pro-cancer state, in which they help promote the tumor’s growth. As a result, attempts... -
Nanoarchitectures for Air Purification
Illnesses caused by air pollution are the third-leading cause of death in developing nations, and over 5 million people worldwide die every year from air pollution exposure. Catalytic converters, the most widely used air purification devices, convert the toxic gases and pollutants produced by fuel combustion into benign chemicals before the exhaust is released into... -
DNA Nanostructures for Drug Delivery
Researchers at the Wyss Institute have developed two methods for building arbitrarily shaped nanostructures using DNA, with a focus on translating the technology towards nanofabrication and drug delivery applications. One proprietary nanofabrication technique, called “DNA-brick self-assembly,” uses short, synthetic strands of DNA that work like interlocking Lego® bricks. It capitalizes on the ability to program... -
NanoRx: Mechanically-Activated Drug Targeting
The Wyss team has developed a novel drug targeting nanotechnology that is activated locally by mechanical forces, either endogenous high shear stresses in blood created by vascular occlusion or mechanical energy applied locally using low-energy ultrasound radiation. Today, vascular blockage is the leading cause of death and disability in United States and Europe. Current therapies... -
Inexpensive Super-Resolution Microscopy
Wyss Institute scientists have developed a highly versatile and inexpensive microscopic imaging platform designed to visualize objects with molecular-scale resolution and unprecedented complexity. The DNA-powered imaging technology can reveal the inner workings of cells at the single molecule level, using conventional microscopes found in most laboratories. Key to the Wyss Institute’s DNA-driven imaging super resolution... -
Paper-Based Diagnostics
With the imminent threat of new pandemics and frequent disease outbreaks exemplified by the recent Ebola and Zika epidemics, there is a growing need for low-cost, easily deployable and simple-to-use diagnostic tools. The Wyss Institute has developed paper-based synthetic gene networks as a next generation diagnostic technology for use in global healthcare crises and patient...
News 57
Multimedia 18
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Video/AnimationLiving MaterialsCan we create a world of living materials that have the characteristics of biological systems: self-replication, self-regulation, self-healing, environmental responsiveness and self-sustainability? Engineered Living Materials (ELMs) are defined as engineered materials composed of living cells that form or assemble the material itself or modulate the functional performance of the material in some manner. The proposed Big... -
Video/AnimationCatalytic Nanoarchitectures for Clean AirThe Wyss Institute is developing a new type of coating for catalytic converters that, inspired by the nanoscale structure of a butterfly’s wing, can dramatically reduce the cost and improve the performance of air purification technologies, making them more accessible to all. Credit: Wyss Institute at Harvard University -
Exchange-PAINT: Neurons Up Close and PersonalDNA Exchange Imaging of fixed mouse hippocampal neurons stained sequentially with antibodies recognizing neuronal markers Synapsin I, vGAT, MAP2, pNFH, α-tubulin, acetyl-tubulin, GFAP and nuclear marker DAPI. Credit: Wyss Institute at Harvard University -
Video/AnimationWhat Is BIOMOD?BIOMOD is a biomolecular design competition for students created by the Wyss Institute for Biologically Inspired Engineering at Harvard University. Each year BIOMOD holds a Jamboree, an annual conference at which all BIOMOD teams convene to present their work from the summer. This year’s Jamboree will take place in Genentech Hall at UCSF in San Francisco,... -
Video/AnimationFouling Marine FoulingMarine fouling occurs when organisms attach themselves to underwater objects like boats, rope, pipes and building structures. Mussels are one of the biggest culprits. Once attached, they are difficult to remove, leading to operational downtime, increased energy use and damage. Paints and coatings are currently used to prevent marine fouling, but are frequently toxin-based and not... -
Audio/PodcastWilliam Shih: Lego-Style Construction of Future Therapeutics From DNAListen to Wyss Core Faculty member William Shih’s lecture on how custom molecular shapes can be designed using DNA building blocks and how these minuscule devices could have a profound impact on fields ranging from molecular biophysics to therapeutics to nano-optics for decades to come. Shih’s lecture is part of the ArtScience lecture series at...