To put disease-related biomarkers to work in the clinic, new high-performance technologies are needed to enable rapid and sensitive analysis of clinical specimens. Please join Dr. Shana Kelley as she discusses how her group uses aspects of biophysical and materials chemistry to create new systems that permit biomolecular analytes and rare cells to be tracked and profiled. Nanomaterials play a central role in these efforts, as the unique properties of materials engineered at the nanoscale allow previously unreachable levels of sensitivity and specificity to be realized.