Focus Area: 3D Organ Engineering
97 Results for '3D Organ Engineering'
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Technologies 9
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ReConstruct: Vascularized tissue for breast reconstruction and augmentation
ReConstruct is a platform for growing, vascularizing, and implanting patient-derived tissues that enable safer breast reconstruction after cancer surgery. -
Reel Foods: Cultivated fillets of fish for healthier people and planet
Reel Foods leverages cardiac tissue engineering methods developed at the Wyss Institute to generate cultivated fish fillets that are indistinguishable from wild-caught seafood, have a lower carbon footprint than traditional fish production, and are free from contaminants like mercury and PFAS. -
Kidney Engineering Technology for New Tissue Replacement Therapies
Trestle Biotherapeutics licensed 3D bioprinting, and stem cell and kidney organoid engineering methods to help it create kidney repair and replacement therapies. These could become new standard-of-care options beyond dialysis and kidney transplants for patients with kidney failure. -
PhonoGraftTM: Biomimetic Hearing-restoration Technology
PhonoGraft is an eardrum-regenerating device that enables better and longer-lasting eardrum reconstruction, reducing the need for invasive surgeries and minimizing the risk of long-term hearing loss. Wyss startup Beacon Bio was acquired by Desktop Health, a healthcare business within Desktop Metal, Inc. which is further developing this technology towards commercialization with the former Wyss startup team leading the way. -
MM3D: Multimaterial Multinozzle 3D Printing
3D printers are revolutionizing manufacturing by allowing users to create any physical shape they can imagine on-demand. However, most extrusion-based printers available commercially are only able to build objects from a single nozzle at a time. Those that can deposit multiple inks are even slower due to the additional time required to switch between materials.... -
Engineered Brain Organoids
The ability to derive and manipulate pluripotent stem cells has opened up new avenues for modeling biological systems in both healthy and diseased conditions. In order to more fully recapitulate the tissue microenvironment with its cell-cell, cell-extracellular matrix, and cell-niche interactions, it is essential to transition stem-cell culturing from monolayers to 3D structures. Self-organization of...
News 62
Multimedia 26
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Video/AnimationESCAPE BioengineeringA research team at the Wyss Institute and Boston University has developed ESCAPE, the first method that enables the engineering of tissues across multiple length scales, ranging from the diameter of a cell to the cm scale of a heart valve. Credit: Wyss Institute at Harvard University -
Video/AnimationProgress, Potential, and Possibilities with Luba Perry, Ph.D. – Bioengineered Breast Reconstruction And AugmentationEach episode of this podcast includes a discussion with fascinating people designing a better tomorrow. Luba Perry, Ph.D. is Co-Founder and CEO of ReConstruct Bio, an innovative venture emerging from Harvard’s Wyss Institute, aimed at redefining the fields of medical reconstruction and aesthetics with an initial application of their groundbreaking technology on breast reconstruction and... -
Video/AnimationReimagine the World – Volume 4 – ReConstruct EditionDenise Skok, a two-time breast cancer survivor, Luba Perry, a scientist at the Wyss Institute, and Samuel Lin, a plastic surgeon collaborating with the Wyss Institute, are all working to reimagine a world where breast cancer patients have better reconstruction options. The ReConstruct project at the Wyss Institute uses adipose tissue assembled from a patient’s... -
Video/AnimationReConstruct – 3D Bioprinted Vascularized Fat Tissues for Breast ReconstructionBreast cancer affects 15% of all women. Current options for breast reconstruction are insufficient and have poor patient outcomes. A research team at the Wyss Institute is addressing this clinical need by fabricating vascularized adipose tissue flaps for therapeutic use. Credit: Wyss Institute at Harvard University -
Video/AnimationPhonoGraft: Programming the eardrum to repair itselfEardrum perforations are a widespread problem affecting millions worldwide. Current standard of care is invasive, involves harvesting an autologous tissue to patch the eardrum, and often requires to revision surgeries, while hearing outcomes remain unsatisfying. What if we could program the eardrum to repair itself after injury? Researchers at the Wyss Institute, Massachusetts Eye and... -
Video/AnimationVoxelated Soft Matter via Multimaterial, Multinozzle 3D PrintingMultimaterial Multinozzle 3D (MM3D) Printing, a new technique developed by engineers at the Wyss Institute and Harvard SEAS, allows seamless switching between up to eight different materials within a single nozzle, allowing for the creation of complex 3D objects in a fraction of the time required by other extrusion-based 3D printing methods. Credit: Wyss Institute...