The lab of Chris Chen, M.D., Ph.D., William Fairfield Warren Distinguished Professor and Founding Director of the Biological Design Center at Boston University, as well as Core Faculty at the Wyss Institute for Biologically Inspired Engineering at Harvard University, seeks outstanding postdoctoral applicants with knowledge and expertise encompassing engineered cellular microenvironments and vascularized functional tissue development.
The project focuses on investigating the development of an engineered product to address liver failure. The proposed solution is built on several next generation technologies, including tools to drive inducible pluripotent stem cell differentiation into all required cells of the liver, immune engineering to allow allogeneic cells to evade immune rejection, bioreactors to facilitate manufacturing and maturation of cells and engineered tissues at low cost, and simple biofabrication technologies to build clinical-scale constructs.