15 Results for 'Adeno-Associated Virus (AAV)'
MRBL: Next-Generation Gene Therapy for Molecular Skin Rejuvenation
The next-generation gene therapy for molecular skin rejuvenation combines a comprehensive target gene prediction with a novel transdermal delivery approach for therapeutic adenovirus-associated viruses. The platform targets monogenic disease indications in the skin, and extends the same targets to the treatment of common skin aging conditions.
Synthetic Adeno-Associated Virus (AAV) Capsids for Advanced Gene Therapy
Dyno Therapeutics is aiming to become a leading gene therapy delivery partner for companies in this space, and to enable a new generation of more effective, safer gene therapies by harnessing optimized AAV capsids.
Video/AnimationImproving Canine HealthspanA Wyss Institute technology that can treat multiple age-related diseases is now being developed by Rejuvenate Bio into a treatment for mitral valve disease and other deadly conditions in dogs, with the goal of helping man’s best friend live longer, healthier lives. Credit: Wyss Institute at Harvard University
Video/AnimationAAV Capsid EngineeringWyss researchers have created a high-throughput platform to generate an Adeno-associated virus 2 (AAV2) library containing 200,000 variants, each carrying a distinct mutation in the virus capsid protein. Their analysis identified capsid changes that enhanced “homing” potential to specific organs in mice and virus viability, as well as a new protein hidden in the capsid-encoding...
May 16 → 19, 2018
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Wyss Core Faculty member George Church and Wyss team members Eric Kelsic, Kai Chan and Pierce Ogden will speak about their work on AAV capsid engineering as part of this year’s American Society of Gene and Cell Therapy Annual Meeting. Please visit the ASGCT Annual Meeting website, for more information related to the meeting and...