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Technologies 1

• abbieSense: Anaphylaxis Diagnostic
  The molecule histamine plays a primary role in the anaphylaxis reaction, which is a major cause of illness and death in people with severe allergies. Histamine is a very small molecule composed of only seventeen atoms, making it a challenging target to detect. To date, no diagnostic test exists that can measure histamine levels accurately...

News 9

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• Translation News
  
  Cantex licenses intellectual property from Harvard University to develop repurposed drug identified by Wyss Institute to treat inflammatory lung diseases including COVID-19
  February 23, 2022
• Press Release
  
  Cystic fibrosis faithfully modeled in a human Lung Airway Chip
  November 19, 2021
• Press Release
  
  Predicting influenza virus evolution in a human Lung Airway Chip
  September 20, 2021

Multimedia 3

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  Video/Animation
  How do we make safer and more effective drugs?
  Wyss researchers are using an ever-growing number of human tissue-mimicking Organ Chips to improve and accelerate the drug development process for a wide number of unmet diseases – and understand what causes them to erupt. More recently, they added a human Vagina Chip and personalized Barrett’s esophagus Chip to their arsenal, and created in vitro...

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  Video/Animation
  Beating Back the Coronavirus: FDA-Approved Drug Repurposing Pipeline
  With the goal of rapidly repurposing FDA-approved drugs to treat COVID-19, the Wyss Institute is collaborating with the Frieman Lab at the University of Maryland Medical School and the tenOever Lab at the Icahn School of Medicine at Mount Sinai to establish a multidisciplinary pipeline that can rapidly predict, test, and validate potential treatments. Credit:...

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  Video/Animation
  Small Airway-on-a-Chip: Modeling COPD and Asthma
  Development of new therapeutics for chronic lung diseases have been hindered by the inability to study them in vitro. To address this challenge, Wyss Institute researchers used their Organ-on-a-Chip technology to produce a microfluidic ‘human lung small airway-on-a-chip.’ The device, which is composed a clear rubber material, is lined by living Human lung small airway...