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Technologies 1

• Inexpensive Super-Resolution Microscopy
  Wyss Institute scientists have developed a highly versatile and inexpensive microscopic imaging platform designed to visualize objects with molecular-scale resolution and unprecedented complexity. The DNA-powered imaging technology can reveal the inner workings of cells at the single molecule level, using conventional microscopes found in most laboratories. Key to the Wyss Institute’s DNA-driven imaging super resolution...

News 4

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• Press Release
  
  Lighting up proteins with Immuno-SABER
  August 19, 2019
• Press Release
  
  SABER tech gives DNA and RNA visualization a boost
  May 20, 2019
• Video/​Animation
  
  PAINT-ing the future of fluorescence imaging
  February 9, 2018

Multimedia 3

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  Video/Animation
  Lighting up proteins with Immuno-SABER
  This animation explains how Immuno-SABER uses the Primer Exchange Reaction (PER) to enable the simultaneous visualization of multiple proteins in tissues in different applications. Credit: Wyss Institute at Harvard University.

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  Video/Animation
  SABER-FISH: Enabling the sensitive and multiplexed detection of nucleic acids within thick tissues
  This animation shows how SABER-FISH uses a suite of DNA nanotechnological methods that together enable the sensitive and multiplexed detection of DNA and RNA targets within cells and thick tissues. Credit: Wyss Institute at Harvard University

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  Exchange-PAINT: Neurons Up Close and Personal
  DNA Exchange Imaging of fixed mouse hippocampal neurons stained sequentially with antibodies recognizing neuronal markers Synapsin I, vGAT, MAP2, pNFH, α-tubulin, acetyl-tubulin, GFAP and nuclear marker DAPI. Credit: Wyss Institute at Harvard University