174 Results for 'Manufacturing'
Regenerating heart valves
The human heart beats approximately 35 million times every year, pumping blood into the circulation via four different heart valves. In more than four million people each year, heart valves fail for different reasons, including birth defects, age-related deteriorations and infections. At present, clinicians use either artificial prostheses or fixed animal and cadaver-sourced tissue to...
Manufacturing biomolecules ‘on the go’
Wyss Institute researchers have developed a biomolecular manufacturing method that can quickly and easily produce a wide range of vaccines, antimicrobial peptides and antibody conjugates while doing so anywhere, even in places without access to electrical power or refrigeration. The breakthrough could provide a life-saving workaround for making modern interventions available in remote areas. Today...
DNA Nanostructures for Drug Delivery
Researchers at the Wyss Institute have developed two methods for building arbitrarily shaped nanostructures using DNA, with a focus on translating the technology towards nanofabrication and drug delivery applications. One proprietary nanofabrication technique, called “DNA-brick self-assembly,” uses short, synthetic strands of DNA that work like interlocking Lego® bricks. It capitalizes on the ability to program...
Ultra-Strong Flexible Biomaterials
Hydrogels are already being developed for use as scaffolds for tissue engineering, vehicles for drug delivery, actuators for optics and fluidics, and models for biological studies of tissue-supporting material called the extracellular matrix. But these water-rich polymer gels are weak; they rupture if stretched just a little, and they break easily compared with resilient biological...
High Density Information Storage in DNA
A new method developed at the Wyss Institute allows for synthesis of oligonucleotides by the thousands on a single DNA microchip — a collection of thousands of different DNA segments attached to a glass slide or other solid surface. Until now, generating long strands of DNA has been challenging and labor-intensive. Yet Wyss researchers have...
Dynamic Daylight Control System
In the U.S. alone, commercial and residential buildings account for more than 40 percent of the total energy consumption – mostly for lighting. What’s more, the deep building layouts that are typical in the U.S. have led to a complete reliance on artificial lighting systems that are less desirable than natural daylight. Many of the...