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Technologies 3

• Cellular “Backpacks” to Slow Tumor Growth
  Macrophages are the body’s multipurpose defense agents, patrolling for pathogens and engulfing cellular debris, foreign substances, microbes, and even cancer cells. But cancerous tumors have evolved an insidious defense mechanism: they can switch arriving macrophages from an anti-cancer state to a pro-cancer state, in which they help promote the tumor’s growth. As a result, attempts...
• Nanoarchitectures for Air Purification
  Illnesses caused by air pollution are the third-leading cause of death in developing nations, and over 5 million people worldwide die every year from air pollution exposure. Catalytic converters, the most widely used air purification devices, convert the toxic gases and pollutants produced by fuel combustion into benign chemicals before the exhaust is released into...
• NanoRx: Mechanically-Activated Drug Targeting
  The Wyss team has developed a novel drug targeting nanotechnology that is activated locally by mechanical forces, either endogenous high shear stresses in blood created by vascular occlusion or mechanical energy applied locally using low-energy ultrasound radiation. Today, vascular blockage is the leading cause of death and disability in United States and Europe. Current therapies...

News 12

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• Press Release
  
  Turning the problem of cancer metastasis into an opportunity
  November 16, 2020
• Translation News
  
  Metalmark launches to make clean air affordable for all
  September 1, 2020
• Press Release
  
  Better vaccines are in our blood
  July 13, 2020

Multimedia 2

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  Video/Animation
  Catalytic Nanoarchitectures for Clean Air
  The Wyss Institute is developing a new type of coating for catalytic converters that, inspired by the nanoscale structure of a butterfly’s wing, can dramatically reduce the cost and improve the performance of air purification technologies, making them more accessible to all.  Credit: Wyss Institute at Harvard University  

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  Video/Animation
  NanoRx: Clot-Busting Nanotherapeutic
  In this animation, learn how the Wyss Institute clot-busting nanotherapeutic is activated by fluid high shear force – which occurs where blood flows through vessels narrowed by obstruction – to specifically target clots and dissolve them away. By pairing this drug with an intra-arterial device that restores blood flow to complete obstructions, the drug-device combination...