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Technologies 3

• StopEndoPain: Therapeutics for Endometriosis Associated Pain
  Endometriosis is a common disease affecting 10% of women globally, making it one of the largest unaddressed indications in the world. It is associated with infertility and significant, frequently debilitating pain. Understanding its pain mechanisms is critical for targeted endometriosis treatments. We are developing in vitro models of ectopic endometrial lesions and studying connections to...
• Vagina-Brain Axis: Treating Hormone Imbalance-Related Diseases
  Microbes in our gut have been shown to impact the brain, which is the control center for most of the body’s functions. Research shows that the gut microbiome affects our mood and mental health, including depression. This regulation is called the gut-brain axis. Other organs beyond the gut — including those in the female genital...
• IBD ID: Finding Novel Anti-Inflammatory Drugs
  Inflammatory Bowel Disease (IBD) disproportionately affects women, who also experience IBD symptoms differently than men. Through research with human Organ Chips, we identified the role of connective tissue in aggravating inflammation in the nearby intestinal cells of IBD patients. We will use this chip technology to enable rapid screening of stromal cells, crucial for understanding...