Search results for: Toxicology | Wyss Institute

Wyss Institute Search Site

Video/Animation

Interrogator: Human Organ-on-Chips
This video describes the “Interrogator” instrument that can be programmed to culture up to 10 different Organ Chips and sequentially transfer fluids between their vascular channels to mimic normal human blood flow between the different organs of our body. Its integrated microscope enables the continuous monitoring of the tissues’ integrities in the individual organ chips...
Video/Animation

Kidney Organiods: Flow-Enhanced Vascularization and Maturation In Vitro
This video explains how the collaborative project created vascularized kidney organoids and how they advance the field of tissue engineering. Credit: Wyss Institute at Harvard University.
Video/Animation

This is Your Brain on Chips
How do you study something as complex as the human brain? Take it apart. Wyss researchers have created Organ Chips that mimic the blood-brain barrier and the brain and, by linking them together, discovered how our blood vessels and our neurons influence each other. Credit: Wyss Institute at Harvard University
Video/Animation

3D Printed Heart-on-a-Chip
In this video, learn how Wyss Institute and Harvard SEAS researchers have created a 3D-printed heart-on-a-chip that could lead to new customizable devices for short-term and long-term in vitro testing. Credit: Johan U. Lind (Disease Biophysics Group), Alex D. Valentine and Lori K. Sanders (Lewis Lab)/Harvard University
Video/Animation

Bioprinting: The Kidney’s Proximal Tubules
In this video, see how the Wyss Institute team has advanced bioprinting to the point of being able to fabricate a functional subunit of a kidney. Credit: Wyss Institute at Harvard University
Video/Animation

Human Organs-On-Chips
Wyss Institute researchers and a multidisciplinary team of collaborators have engineered microchips that recapitulate the microarchitecture and functions of living human organs, including the lung, intestine, kidney, skin, bone marrow and blood-brain barrier. These microchips, called ‘organs-on-chips’, offer a potential alternative to traditional animal testing. Each individual organ-on-chip is composed of a clear flexible polymer...
Audio/Podcast

Cyborg Microchip Medicine
This edition of Revolutions focuses on Cyborg Microchip Medicine. Dr Don Ingber, Director of the Wyss Institute for Biologically Inspired Engineering at Harvard University is visiting Melbourne University and discussed this revolutionary research with Jon Faine.
Video/Animation

Bioinspired Approach to Sepsis Therapy
Wyss Institute Founding Director Don Ingber, Senior Staff Scientist Michael Super and Technology Development Fellow Joo Kang explain how they engineered the Mannose-binding lectin (MBL) protein to bind to a wide range of sepsis-causing pathogens and then safely remove the pathogens from the bloodstream using a novel microfluidic spleen-like device. Credit: Wyss Institute at Harvard...
Audio/Podcast

Building Organs, On One Microchip At A Time
Building Organs, On One Microchip At A Time was originally broadcast on NPR on July 29, 2012. This story features Wyss Core Faculty member Don Ingber. Original broadcast story can be found here.
Video/Animation

Clot-busting nanotherapeutic
Wyss Core Faculty member Donald E. Ingber describes the clot-busting nanotherapeutic. Credit: Wyss Institute at Harvard University
Video/Animation

Introduction to Organs-on-a-Chip
What if we could test drugs without animal models? Wyss Institute researchers and a multidisciplinary team of collaborators have engineered microchips that recapitulate the microarchitecture and functions of living human organs, including the lung, intestine, kidney, skin, bone marrow and blood-brain barrier. These microchips, called ‘organs-on-chips’, offer a potential alternative to traditional animal testing. Each...
Video/Animation

Introduction to Sepsis Diagnostic
What if we could diagnose sepsis in just hours, not days? Wyss Institute researchers discuss their approach to a rapid sepsis diagnostic. Credit: Wyss Institute at Harvard University
Video/Animation

Lung-on-a-Chip
Combining microfabrication techniques with modern tissue engineering, lung-on-a-chip offers a new in vitro approach to drug screening by mimicking the complicated mechanical and biochemical behaviors of a human lung. This extended version of the video includes our findings when we mimicked pulmonary edema on the chip. Credit: Wyss Institute at Harvard University