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29 Results for 'brain'
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Audio/PodcastBrain Shuttles: A New Path Into the Brain with James Gorman of the Wyss InstituteThe host of Business Trip, Matias Serebrinsky, interviews Wyss Senior Director of Translational R&D James (Jim) Gorman, M.D., Ph.D. Jim is a Principal Investigator of the Wyss Institute Brain Targeting Program (BTP). He leads a team developing new approaches to transport drugs through the blood-brain barrier (BBB) into the central nervous system. In this episode,... -
Video/AnimationHow can we better treat brain diseases?The Brain Targeting Program at the Wyss Institute is a pre-competitive, multi-partner industry collaboration that aims to identify novel transport targets and shuttle compounds to enable more effective delivery of drugs to the brain. Credit: Wyss Institute at Harvard University -
Audio/PodcastCan we grow a conscious brain? – CrowdSciencePhilosophers have long pondered the concept of a brain in a jar, hooked up to a simulated world. Though this has largely remained a thought experiment, CrowdScience listener JP wants to know if it might become reality in the not-too-distant future, with advances in stem cell research. In the two decades since stem cell research... -
Video/AnimationWyss Institute Brain Targeting ProgramThis animation explains how Wyss Institute researchers and their industry partners aim to identify novel transport targets and shuttle compounds to enable more effective delivery of drugs to the brain. Credit: Wyss Institute at Harvard University. -
Video/AnimationEliminating brain cancer at its source | Natalie Artzi | TEDxMITGlioblastoma is a lethal, aggressive brain cancer with a dismal median overall survival rate of 15 months, a number that has remained unchanged for decades. Treatment for this devastating disease involves surgical resection followed by chemotherapy and radiation therapy; however, tumor recurrence is inevitable as it is impossible to eliminate all tumor cells with current... -
Video/AnimationSoft Robotic Gripper for Jellyfish 2.0Scientists from the Wyss Institute at Harvard University and CUNY have created ultra-soft robotic grippers that resemble fettuccini noodles to safely catch and release delicate underwater creatures like jellyfish without harm. Credit: Wyss Institute at Harvard University -
Video/AnimationThis is Your Brain on ChipsHow do you study something as complex as the human brain? Take it apart. Wyss researchers have created Organ Chips that mimic the blood-brain barrier and the brain and, by linking them together, discovered how our blood vessels and our neurons influence each other. Credit: Wyss Institute at Harvard University
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Video/AnimationCure ALD – Behind the Research | Alex LeNail – Safer Gene TherapyLearn about Wyss Postdoctoral Fellow Alex LeNail‘s background and how he plans to develop a safer gene therapy for ALD (adrenoleukodystrophy) patients. If successful, this could go to clinical trials and give families hope for a cure. This video series tells the story of the scientists behind the breakthroughs, and why community-driven fundraising is the... -
Video/AnimationReimagining Neurodegenerative Disease Treatment for Her Grandfather: Mariana Garcia-CorralMariana Garcia-Corral is a Research Assistant studying brain organoids to help with the treatment of bipolar disorder. In this video, she shares a poignant personal story about her grandfather suffering from Lewy body dementia and how she would Reimagine a World with better neurodegenerative disease treatment. Credit: Wyss Institute at Harvard University -
Audio/PodcastBuying time: A medical breakthrough in stroke treatmentWhen a stroke strikes, every minute matters. Science has traditionally approached stroke as a race against time. But rather than racing faster, what if we could instead slow the damage down? Join host Shahni Wellington as she explores groundbreaking research aimed at buying more time for stroke patients, particularly those in rural and regional communities.... -
Video/AnimationAtlantic Health Research Spotlight: Finding Balance in Bipolar Disorder Through Drug Prediction and Organoid-Based Drug ScreeningInnovation has disrupted care as we know it. Challenges with access, complex diseases, and care delivery persist, but so do areas of opportunity for emerging tech and discoveries. The Atlantic explored gene editing, artificial intelligence, climate change, weight-loss and diabetes treatments, and more at their Annual Health Summit. The Wyss’ Director of Synthetic Biology, Jenny... -
Video/AnimationReimagine the World: Volume 1Four Wyss Institute scientists, Mariana Garcia-Corral, Pawan Jolly, Megan Sperry, and Mike Super, share how they would Reimagine the World and the personal stories that fuel their passion for the work they are doing. We’d love to hear how you would Reimagine the World! Please visit the following link to share your ideas: https://wyss.typeform.com/to/o9xM7cG1 Credit:... -
Video/Animation20-ish Questions with Ellen Roche20-ish Questions shows a different side of Wyss Institute faculty, touching on aspects of their personal life, hobbies, interests, as well as their research. This round follows Ellen Roche, an Associate Faculty member of the Wyss Institute as well as the Latham Family Career Development Professor at the Department of Mechanical Engineering and the Institute... -
Video/AnimationFinding a Balance In Bipolar Disorder Through Drug Prediction and Organoid-Based Drug ScreeningCircaVent is a high-throughput drug screening platform that combines predictive algorithms, preclinical models, and human brain organoids to efficiently identify and test drugs that could treat the underlying causes of bipolar disorder. CircaVent is initially focused on addressing the circadian rhythm disruptions that are a common hallmark of BD, and could dramatically speed up the... -
Video/AnimationAtlantic Health Research Spotlight: Novel Anesthetics for Care in Battlefield and Disaster AreaThe Atlantic’s Health Summit returned to Boston in 2025 for their annual exploration of the urgent issues reshaping the healthcare landscape. The event showcased recent breakthroughs that are redefining medical practices and explored the challenges of scaling innovation and implementing sustainable solutions. Speakers explored early disease detection, novel anesthetics, pain management, AI and drug discovery,... -
Video/AnimationWyss Study: Memory GenesResearchers at the Wyss Institute and the Personal Genome Project (PGP) are using Lumosity games to evaluate memory functions and response times. The genomes of high performers will be sequenced, with the goal of uncovering the relationship between genetics, memory, attention, and reaction speed. This video featuring George Church, Core Faculty of the Wyss Institute and Professor... -
Video/AnimationCogniXense: Speeding Up Treatments for Rare DiseasesAt the Wyss Institute, we are tackling Rett syndrome, a rare disease that affects 1 out of 9,000 children, by developing a scalable model for neurodevelopmental and cognitive diseases. This model can test drugs to see which will improve memory, learning, and behavior, with the end goal of finding effective therapies. Credit: Wyss Institute at... -
Video/AnimationGyrification: How the Brain Got its FoldsA team led by Wyss Institute Core Faculty member L. Mahadevan used numerical simulations and a physical gel model to answer an age-old question that has vexed scientists for years: how did the outer layer of the mammalian brain (gray matter) become so convoluted atop the brain’s inner white matter? It turns out that at... -
Video/AnimationHow Humans Walk…With RobotsResearchers at the Wyss Institute and Spaulding Rehabilitation Hospital shed light on how humans respond – or do not respond – to forces applied by rehabilitative robots. Credit: Wyss Institute at Harvard University -
Video/AnimationMulti-joint Personalized Soft Exosuit Breaks New GroundA multidisciplinary team at Harvard’s Wyss Institute and Harvard SEAS has developed a mobile multi-joint soft exosuit using an automatic tuning strategy that could reduce fatigue in soldiers, firefighters or other rescue workers. Credit: Wyss Institute at Harvard University -
Video/AnimationSoft Exosuit for Post-stroke Gait Re-trainingThis video explains how exosuit technology, developed at the Wyss Institute for Biologically Inspired Engineering, applied to ankle movements helps patients post-stroke regain a more normal gait. Credit: Wyss Institute at Harvard University -
Video/AnimationFluorescent in situ SequencingIn this video, George Church, Ph.D., a Core Faculty member at the Wyss Institute and Professor of Genetics at Harvard Medical School, explains how fluorescent in situ sequencing could lead to new diagnostics that spot the earliest signs of disease, and how it could help reveal how neurons in the brain connect and function. Credit:... -
Video/AnimationNanoRx: Clot-Busting NanotherapeuticIn this animation, learn how the Wyss Institute clot-busting nanotherapeutic is activated by fluid high shear force – which occurs where blood flows through vessels narrowed by obstruction – to specifically target clots and dissolve them away. By pairing this drug with an intra-arterial device that restores blood flow to complete obstructions, the drug-device combination... -
Video/AnimationNeuroAssessA team at Harvard’s Wyss Institute and Beth Israel Deaconess have developed a computer tablet application that could rapidly and quantitatively assess neuromuscular performance. Credit: Wyss Institute at Harvard University -
Video/AnimationClot-busting nanotherapeuticWyss Core Faculty member Donald E. Ingber describes the clot-busting nanotherapeutic. Credit: Wyss Institute at Harvard University -
Video/AnimationWhen Matter Makes Decisions: Michael Levin on the Intelligence of FormIn this episode of Grow Everything, hosts Karl Schmieder and Erum Azeez Khan have a conversation with Professor Michael Levin, Ph.D., Wyss Associate Faculty member and the Director of the Allen Discovery Center at Tufts University. He reveals how cells make decisions without brains, store memories without DNA, and navigate anatomical space like we navigate... -
Video/AnimationThe Human Mind and Gait ControlResearchers study how our brains adjust to changes in our walking strides, gaining insights that could be used to develop better physical rehabilitation programs. Credit: Wyss Institute -
Video/AnimationHuman Organs-On-ChipsWyss Institute researchers and a multidisciplinary team of collaborators have engineered microchips that recapitulate the microarchitecture and functions of living human organs, including the lung, intestine, kidney, skin, bone marrow and blood-brain barrier. These microchips, called ‘organs-on-chips’, offer a potential alternative to traditional animal testing. Each individual organ-on-chip is composed of a clear flexible polymer... -
Video/AnimationIntroduction to Organs-on-a-ChipWhat if we could test drugs without animal models? Wyss Institute researchers and a multidisciplinary team of collaborators have engineered microchips that recapitulate the microarchitecture and functions of living human organs, including the lung, intestine, kidney, skin, bone marrow and blood-brain barrier. These microchips, called ‘organs-on-chips’, offer a potential alternative to traditional animal testing. Each...