Search Results for “organ-on-a-chip”

February 27, 2023
Biochemical Journal
From tensegrity to human organs-on-chips: implications for mechanobiology and mechanotherapeutics

Donald E Ingber
December 27, 2023
Pharmacology, Research, & Perspectives
Human organ chips for regenerative pharmacology

Girija Goyal, Chaitra Belgur, Donald E. Ingber
July 19, 2022
Physiology
What Can an Organ-on-a-Chip Teach Us About Human Lung Pathophysiology?

Haiqing Bai, Donald E Ingber
June 6, 2022
Physiology
What can an organ-on-a-chip teach us about human lung physiology?

Haiqing Bai and Donald E. Ingber
March 25, 2022
Nature Reviews Genetics
Human organs-on-chips for disease modelling, drug development and personalized medicine

Donald E. Ingber
August 27, 2024
Nature Reviews Gastroenterology & Hepatology
Intestinal organ chips for disease modelling and personalized medicine

Alican Özkan, Nina Teresa LoGrande, Jessica F. Feitor, Girija Goyal & Donald E. Ingber
August 4, 2021
Lab on a Chip
Simulating drug concentrations in PDMS microfluidic organ chips

Jennifer Grant, Alican Özkan, Crystal Oh, Gautam Mahajan, Rachelle Prantil-Baun, Donald E Ingber
February 5, 2025
Lab on a Chip
TapeTech microfluidic connectors: adhesive tape-enabled solution for organ-on-a-chip system integration

Terry Chin, Abraham C I van Steen, Delaney Gray-Scherr, Jessica L Teo, Anish Vasan, Joshua Jeon, Jessica Shah, Aayush Pate, Amy E Stoddard, Jennifer L Bays, Jeroen Eyckmans, Christopher S Chen
April 12, 2022
Lab on a Chip
Establishment of physiologically relevant oxygen gradients in microfluidic organ chips

Jennifer Grant, Elizabeth Lee, Micaela Almeida, Seongmin Kim, Nina LoGrande, Girija Goyal, Adama Marie Sesay, David T Breault, Rachelle Prantil-Baun, Donald E Ingber
October 12, 2020
Advanced Science
Is it Time for Reviewer 3 to Request Human Organ Chip Experiments Instead of Animal Validation Studies?

Donald E. Ingber
May 25, 2025
Journal of Translational Medicine
Patient-derived esophageal adenocarcinoma organ chip: a physiologically relevant platform for functional precision oncology

Sanjima Pal, Elee Shimshoni, Salvador Flores Torres, Mingyang Kong, Kulsum Tai, Veena Sangwan, Nicholas Bertos, Swneke Donovan Bailey, Julie Bérubé, Donald E. Ingber & Lorenzo Ferri
July 13, 2020
Trends in Microbiology
Human Organs-on-Chips for Virology

Huaqi Tang, Yasmine Abouleila, Longlong Si, Ana Maria Ortega-Prieto, Christine L. Mummery, Donald E. Ingber, Alireza Mashaghi
January 15, 2019
Nature Reviews Cancer
Modelling cancer in microfluidic human organs-on-chips

Alexandra Sontheimer-Phelps, Bryan A. Hassell & Donald E. Ingber
May 18, 2018
Development
Developmentally inspired human ‘organs on chips’

Donald E. Ingber
August 17, 2024
Biosensors and Bioelectronics
Organ chips with integrated multifunctional sensors enable continuous metabolic monitoring at controlled oxygen levels

Zohreh Izadifar, Berenice Charrez, Micaela Almeida, Stijn Robben, Kanoelani Pilobello, Janet van der Graaf-Mas, Susan L Marquez, Thomas C Ferrante, Kostyantyn Shcherbina, Russell Gould, Nina T LoGrande, Adama M Sesay, Donald E Ingber
June 6, 2023
Gastro Help Advances
Epithelial-Stromal Interactions in Barrett’s Esophagus Modeled in Human Organ Chips

E. Shimshoni, G.E. Merry, Z.D. Milot, C.Y. Oh, V. Horvath, R.A. Gould, J.A. Caruso, C. Chen-Tanyolac, P. Gascard, V. Sangwan, J. Bérubé, S.D. Bailey, S. Hall, M.D. Stachler, L. Ferri, T.D. Tlsty, D.E. Ingber
September 27, 2022
Advanced Drug Delivery Reviews
Modeling mucus physiology and pathophysiology in human organs-on-chips

Zohreh Izadifar, Alexandra Sontheimer-Phelps, Bob A Lubamba, Haiqing Bai, Cicely Fadel, Anna Stejskalova, Alican Ozkan, Queeny Dasgupta, Amir Bein, Abidemi Junaid, Aakanksha Gulati, Gautam Mahajan, Seongmin Kim, Nina T LoGrande, Arash Naziripour, Donald E Ingber
January 10, 2020
Nature Protocols
Biomimetic smoking robot for in vitro inhalation exposure compatible with microfluidic organ chips

Kambez H. Benam, Richard Novak, Thomas C. Ferrante, Youngjae Choe & Donald E. Ingber
August 29, 2019
Hepatology
A Bile Duct-on-a-Chip with Organ-Level Functions

Yu Du, Gauri Khandekar, Jessica Llewellyn, William Polacheck, Christopher S. Chen, Rebecca G. Wells
January 11, 2019
Lab on a Chip
Non-invasive sensing of transepithelial barrier function and tissue differentiation in organs-on-chips using impedance spectroscopy.

van der Helm MW, Henry OYF, Bein A, Hamkins-Indik T, Cronce MJ, Leineweber WD, Odijk M, van der Meer AD, Eijkel JCT, Ingber DE, van den Berg A, Segerink LI.
March 14, 2022
Advanced Science
Ectopic Lymphoid Follicle Formation and Human Seasonal Influenza Vaccination Responses Recapitulated in an Organ-on-a-Chip

Girija Goyal, Pranav Prabhala, Gautam Mahajan, Bruce Bausk, Tal Gilboa, Liangxia Xie, Yunhao Zhai, Roey Lazarovits, Adam Mansour, Min Sun Kim, Aditya Patil, Danielle Curran, Jaclyn M. Long, Sanjay Sharma, Abidemi Junaid, Limor Cohen, Thomas C. Ferrante, Oren Levy, Rachelle Prantil-Baun, David R. Walt, Donald E. Ingber
August 6, 2013
Lab on a Chip
Organs on chips

Beebe DJ, den Toonder J, Ingber DE
April 24, 2018
Cellular and Molecular Gastroenterology and Hepatology
Microfluidic Organ-on-a-Chip Models of Human Intestine

Bein A, Shin W, Jalili-Firoozinezhad S, Park MH, Sontheimer-Phelps A, Tovaglieri A, Chalkiadaki A, Kim HJ, Ingber DE.
October 20, 2018
JoVE
Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips

Richard Novak, Meredyth Didier, Elizabeth Calamari, Carlos F Ng, Youngjae Choe, Susan L Clauson, Bret A Nestor, Jefferson Puerta, Rachel Fleming, Sasan J Firoozinezhad, Donald E Ingber
August 5, 2014
Nature Biotechnology
Microfluidic organs-on-chips.

Bhatia SN, Ingber DE
March 6, 2016
Cell
Reverse Engineering Human Pathophysiology with Organs-on-Chips

Ingber DE
January 6, 2018
Annual Reviews of Pharmacology and Toxicology
Physiologically Based Pharmacokinetic and Pharmacodynamic Analysis Enabled by Microfluidically Linked Organs-on-Chips.

Prantil-Baun R, Novak R, Das D, Somayaji MR, Przekwas A, Ingber DE.
May 3, 2012
Lab on a Chip
Microengineered physiological biomimicry: Organs-on-Chips

Huh D, Torisawa YS, Hamilton GA, Kim HJ, Ingber DE
May 30, 2017
Lab on a Chip
Organs-on-chips with integrated electrodes for trans-epithelial electrical resistance (TEER) measurements of human epithelial barrier function

Olivier Y. F. Henry, Remi Villenave, Michael J. Cronce, William D. Leineweber, Maximilian A. Benz and Donald E. Ingber
October 6, 2016
Clinical Pharmacology & Therapeutics
Organ Chips: Quality Assurance Systems in Regenerative Medicine

Pasqualini FS, Emmert MY, Parker KK, Hoerstrup SP
October 26, 2011
Trends in Cell Biology
From 3D cell culture to organs-on-chips

Dongeun Huh, Geraldine A. Hamilton, Donald E. Ingber
July 11, 2013
Current Opinion in Pharmacology
Organs-on-a-chip for drug discovery.

Selimovic S, Dokmeci MR, Khademhosseini A
January 16, 2018
Biofabrication
Automated fabrication of photopatterned gelatin hydrogels for organ-on-chips applications.

Nawroth JC, Scudder LL, Halvorson RT, Tresback J, Ferrier JP, Sheehy SP, Cho A, Kannan S, Sunyovszki I, Goss JA, Campbell PH, Parker KK.
June 7, 2017
Lab on a Chip
Organs-on-Chips with combined multi-electrode array and transepithelial electrical resistance measurement capabilities

Ben M. Maoz, Anna Herland, Olivier Y. F. Henry, William D. Leineweber, Moran Yadid, John Doyle, Robert Mannix, Ville J. Kujala, Edward A. FitzGerald, Kevin Kit Parker and Donald E. Ingber
October 10, 2017
Cell Reports
Human Organ Chip Models Recapitulate Orthotopic Lung Cancer Growth, Therapeutic Responses, and Tumor Dormancy In Vitro

Bryan A. Hassell, Girija Goyal, Esak Lee, Alexandra Sontheimer-Phelps, Oren Levy, Christopher S. Chen, Donald E. Ingber
January 27, 2020
Nature Biomedical Engineering
Quantitative prediction of human pharmacokinetic responses to drugs via fluidically coupled vascularized organ chips

Anna Herland, Ben M. Maoz, Debarun Das, Mahadevabharath R. Somayaji, Rachelle Prantil-Baun, Richard Novak, Michael Cronce, Tessa Huffstater, Sauveur S. F. Jeanty, Miles Ingram, Angeliki Chalkiadaki, David Benson Chou, Susan Marquez, Aaron Delahanty, Sasan Jalili-Firoozinezhad, Yuka Milton, Alexandra Sontheimer-Phelps, Ben Swenor, Oren Levy, Kevin K. Parker, Andrzej Przekwas & Donald E. Ingber
November 8, 2013
Nature Protocols
Microfabrication of human organs-on-chips.

Huh D, Kim HJ, Fraser JP, Shea DE, Khan M, Bahinski A, Hamilton GA, Ingber DE
March 10, 2015
Nanomedicine (London, England)
Seeking the right context for evaluating nanomedicine: from tissue models in petri dishes to microfluidic organs-on-a-chip.

Zhang YS, Khademhosseini A
March 26, 2017
Experimental Biology and Medicine
Toward improved myocardial maturity in an organ-on-chip platform with immature cardiac myocytes

Sheehy SP, Grosberg A, Qin P, Behm DJ, Ferrier JP, Eagleson MA, Nesmith AP, Krull D, Falls JG, Campbell PH, McCain ML, Willette RN, Hu E, Parker KK.
June 25, 2010
Science
Reconstituting Organ-Level Lung Functions on a Chip

Dongeun Huh, Benjamin D. Matthews, Akiko Mammoto, Mart¥Ë__n Montoya-Zavala, Hong Yuan Hsin, and Donald E. Ingber
March 12, 2014
Expert opinion on drug discovery
Organs-on-a-chip: a new tool for drug discovery.

Polini A, Prodanov L, Bhise NS, Manoharan V, Dokmeci MR, Khademhosseini A
August 20, 2018
Nature Biotechnology
A linked organ-on-chip model of the human neurovascular unit reveals the metabolic coupling of endothelial and neuronal cells

Ben M Maoz, Anna Herland, Edward A FitzGerald, Thomas Grevesse, Charles Vidoudez, Alan R Pacheco, Sean P Sheehy, Tae-Eun Park, Stephanie Dauth, Robert Mannix, Nikita Budnik, Kevin Shores, Alexander Cho, Janna C Nawroth, Daniel Segrè, Bogdan Budnik, Donald E Ingber & Kevin Kit Parker
April 30, 2018
Clinical Pharmacology & Therapeutics
Organ‐on‐Chip Recapitulates Thrombosis Induced by an anti‐CD154 Monoclonal Antibody: Translational Potential of Advanced Microengineered Systems

Riccardo Barrile, Andries D. van der Meer, Hyoungshin Park, Jacob P. Fraser, Damir Simic, Fang Teng, David Conegliano, Justin Nguyen, Abhishek Jain, Mimi Zhou, Katia Karalis, Donald E. Ingber, Geraldine A. Hamilton, Monicah A. Otieno
May 10, 2014
Journal of Controlled Release
Organ-on-a-chip platforms for studying drug delivery systems.

Bhise NS, Ribas J, Manoharan V, Zhang YS, Polini A, Massa S, Dokmeci MR, Khademhosseini A
November 27, 2014
Lab on a Chip
Measuring direct current trans-epithelial electrical resistance in organ-on-a-chip microsystems.

Odijk M, van der Meer AD, Levner D, Kim HJ, van der Helm MW, Segerink LI, Frimat JP, Hamilton GA, Ingber DE, van den Berg A
April 26, 2016
Lab on a Chip
Elastomeric free-form blood vessels for interconnecting organs on chip systems.

Zhang W, Zhang YS, Bakht SM, Aleman J, Shin SR, Yue K, Sica M, Ribas J, Duchamp M, Ju J, Sadeghian RB, Kim D, Dokmeci MR, Atala A, Khademhosseini A
August 18, 2017
Scientific Reports
Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform.

Skardal A, Murphy SV, Devarasetty M, Mead I, Kang HW, Seol YJ, Shrike Zhang Y, Shin SR, Zhao L, Aleman J, Hall AR, Shupe TD, Kleensang A, Dokmeci MR, Jin Lee S, Jackson JD, Yoo JJ, Hartung T, Khademhosseini A, Soker S, Bishop CE, Atala A.
August 26, 2016
Biomicrofluidics
A microfluidic optical platform for real-time monitoring of pH and oxygen in microfluidic bioreactors and organ-on-chip devices.

Mousavi Shaegh SA, De Ferrari F, Zhang YS, Nabavinia M, Binth Mohammad N, Ryan J, Pourmand A, Laukaitis E, Banan Sadeghian R, Nadhman A, Shin SR, Nezhad AS, Khademhosseini A, Dokmeci MR
January 27, 2020
Nature Biomedical Engineering
Robotic fluidic coupling and interrogation of multiple vascularized organ chips

Richard Novak, Miles Ingram, Susan Marquez, Debarun Das, Aaron Delahanty, Anna Herland, Ben M. Maoz, Sauveur S. F. Jeanty, Mahadevabharath R. Somayaji, Morgan Burt, Elizabeth Calamari, Angeliki Chalkiadaki, Alexander Cho, Youngjae Choe, David Benson Chou, Michael Cronce, Stephanie Dauth, Toni Divic, Jose Fernandez-Alcon, Thomas Ferrante, John Ferrier, Edward A. FitzGerald, Rachel Fleming, Sasan Jalili-Firoozinezhad, Thomas Grevesse, Josue A. Goss, Tiama Hamkins-Indik, Olivier Henry, Chris Hinojosa, Tessa Huffstater, Kyung-Jin Jang, Ville Kujala, Lian Leng, Robert Mannix, Yuka Milton, Janna Nawroth, Bret A. Nestor, Carlos F. Ng, Blakely O’Connor, Tae-Eun Park, Henry Sanchez, Josiah Sliz, Alexandra Sontheimer-Phelps, Ben Swenor, Guy Thompson II, George J. Touloumes, Zachary Tranchemontagne, Norman Wen, Moran Yadid, Anthony Bahinski, Geraldine A. Hamilton, Daniel Levner, Oren Levy, Andrzej Przekwas, Rachelle Prantil-Baun, Kevin K. Parker & Donald E. Ingber
March 21, 2017
PNAS
Multisensor-integrated organs-on-chips platform for automated and continual in situ monitoring of organoid behaviors.

Yu Shrike Zhang, Julio Aleman, Su Ryon Shin, Tugba Kilic, Duckjin Kim, Seyed Ali Mousavi Shaegh, Solange Massa, Reza Riahi, Sukyoung Chae, Ning Hu, Huseyin Avci, Weijia Zhang, Antonia Silvestri, Amir Sanati Nezhad, Ahmad Manbohi, Fabio De Ferrari, Alessandro Polini, Giovanni Calzone, Noor Shaikh, Parissa Alerasool, Erica Budina, Jian Kang, Nupura Bhise, Joo Ribas, Adel Pourmand, Aleksander Skardal, Thomas Shupe, Colin E. Bishop, Mehmet Remzi Dokmeci, Anthony Atala, and Ali Khademhosseini

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