Technology Area: Microfluidics

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Technologies 9

Origami-Inspired Radiant Cooling for Improved Thermal Health
Origami-inspired Radiant Cooling devices for a broad range of building interiors use microfluidic water-circuits and foldable designs that increase their surface area to achieve more effective cooling.
Single-Cell Encapsulation for Improved Cell Therapies
Mesenchymal stromal cells (MSCs) are valued for their ability to secrete compounds that modulate the body’s immune system, making them an attractive solution for existing problems with cell therapies including host-vs-graft disease and organ transplant rejections. However, MSCs are rapidly cleared from the body and can come under fire from the immune system. Efforts to...
Liquid-Infused Tympanostomy Tubes
The Problem Acute middle ear infections affect more than 700 million people each year, with children often experiencing the most recurrent and severe symptoms. By the age of three, 25-40% of children have had at least three episodes of acute middle ear infection, which is commonly accompanied by excess fluids accumulating behind the tympanic membrane...
AquaPulse: Portable Off-the-Grid Water Purification
Globally, more than 2 billion people are forced to use a drinking water source that is contaminated with bacteria, parasites, and other pathogens, and an estimated 502,000 people die each year from diarrhea as a result of unsafe water. While a majority of the world has access to improved water sources, many are often contaminated;...
Microfluidic Drug Encapsulation
Because of their large molecular sizes and properties, biologic drugs, be it in the form of monoclonal antibodies that target disease-associated molecules or active proteins and enzymes that may correct deficiencies in the human body, have proven difficult to deploy in many cases. Their therapeutic effects on target cells and tissues often require high and...
Project Abbie
Over 15 million Americans are at risk of anaphylaxis, a severe allergic reaction triggered by exposure to certain foods, materials, medications, and insect bites. Every three minutes, a food reaction sends someone to the emergency room. In most individuals, anaphylactic shock can be prevented by administering the counteracting drug epinephrine, as soon as an attack...

Collaborations 1

Brain Targeting Program
Pre-competitive multi-partner industry collaboration that aims to identify novel transport targets and shuttle compounds to enable more effective delivery of drugs to the brain.

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