Technology Area: Microfluidics
87 Results for 'Microfluidics'
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Technologies 5
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Human Organs-on-Chips
Clinical studies take years to complete and testing a single compound can cost more than $2 billion. Meanwhile, innumerable animal lives are lost, and the process often fails to predict human responses because traditional animal models often do not accurately mimic human pathophysiology. For these reasons, there is a broad need for alternative ways to... -
Microfluidic encapsulation for subcutaneous delivery of viscous drugs
Because of their large molecular sizes and properties, biologic drugs, be it in the form of monoclonal antibodies that target disease-associated molecules or active proteins and enzymes that may correct deficiencies in the human body, have proven difficult to deploy in many cases. Their therapeutic effects on target cells and tissues often require high and... -
Project ABBIE
Over 15 million Americans are at risk of anaphylaxis, a severe allergic reaction triggered by exposure to certain foods, materials, medications and insect bites. Every three minutes a food reaction sends someone to the emergency room. In most individuals, anaphylactic shock can be prevented by administering the counteracting drug, epinephrine. Yet, despite effective treatments, death from... -
Dynamic Daylight Control System
In the U.S. alone, commercial and residential buildings account for more than 40 percent of the total energy consumption – mostly for lighting. What’s more, the deep building layouts that are typical in the U.S. have led to a complete reliance on artificial lighting systems that are less desirable than natural daylight. Many of the... -
3D Bioprinting of Living Tissues
Progress in drug testing and regenerative medicine could greatly benefit from laboratory-engineered human tissues built of a variety of cell types with precise 3D architecture. But production of greater than millimeter sized human tissues has been limited by a lack of methods for building tissues with embedded life-sustaining vascular networks. In this video, the Wyss...
News 57
Multimedia 25
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Video/AnimationThis is Your Brain on ChipsHow do you study something as complex as the human brain? Take it apart. Wyss researchers have created Organ Chips that mimic the blood-brain barrier and the brain and, by linking them together, discovered how our blood vessels and our neurons influence each other. Credit: Wyss Institute at Harvard University -
Video/AnimationMORPH: A new soft material microfabrication processWhat has the ability to move and show its colors, is made only of silicone rubber and manufactured at the millimeter scale? A soft robotic peacock spider. Researchers have combined three different manufacturing techniques to create a novel origami-inspired soft material microfabrication process that goes beyond what existing approaches can achieve at this small scale.... -
Video/AnimationNew Wyss Institute Initiative – 3D Organ EngineeringWyss Institute Core Faculty members Christopher Chen and Jennifer Lewis describe the Wyss Institute’s new initiative focused on organ engineering, which leverages our expertise in biomaterials, tissue engineering, three dimensional biofabrication, and stem cell development. -
Video/AnimationTherapeutic Organ Engineering: Highlights From The 8th Annual Wyss SymposiumThe 8th Annual Wyss International Symposium focused on innovations in therapeutic organ engineering, featuring diverse speakers doing exciting work in 3D organ engineering, materials fabrication, and vascular integration. This video highlights some of the themes discussed in their presentations as well as the advances that are leading to the ultimate goals of developing new approaches... -
Video/Animation8th Annual Wyss Institute Symposium: Therapeutic Organ EngineeringScreened just before the symposium opening, this animation artistically connects concepts of therapeutic organ engineering presented during the event. Credit: Wyss Institute at Harvard University -
Video/AnimationPodocyte Cells: Kidney-on-a-ChipThis video shows a 3-dimensional rendering of the glomerulus-on-a-chip with human stem cell-derived mature podocytes (in green) grown and differentiated in one channel (shown on top) and that extend their processes through the modeled glomerulus basement membrane towards glomerular vascular cells (in magenta) in the parallel running channel (shown on the bottom). Credit: Wyss Institute...